Prof Anthony Isles
@profantisles.bsky.social
#Neuroscience 🧠 | #ImprintedGenes 🧬 | #preclinical models 🐭🧫| MURIDAE lead @mrcmousenetwork.bsky.social | Cardiff University | posting in a personal capacity, mostly about science
https://profiles.cardiff.ac.uk/staff/islesar1
https://profiles.cardiff.ac.uk/staff/islesar1
Reposted by Prof Anthony Isles
A Glorious Frosty Morning. -2°C . Rooks
January 14, 2026 at 10:05 AM
A Glorious Frosty Morning. -2°C . Rooks
Reposted by Prof Anthony Isles
The deadline to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social is rapidly approaching!
➡️ 18th January 2026 ⬅️
➡️ 18th January 2026 ⬅️
📢 Job Alert 📢
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Senior Research Associate at Lancaster University
An opportunity for an academic position as a Senior Research Associate is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
January 12, 2026 at 1:17 PM
The deadline to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social is rapidly approaching!
➡️ 18th January 2026 ⬅️
➡️ 18th January 2026 ⬅️
This looks like a fantastic event, with @britishneuro.bsky.social continuing to drive improvements in the credibility of #neuroscience research 🧠
And it is FREE for #BNA members!!!
And it is FREE for #BNA members!!!
CREDIBILITY ACROSS SECTORS:
Join an incredible line-up of speakers next month to explore how credible research is applied across academia, industry, biotech, and clinical trials.
Register now: bna.org.uk/events/ems-e...
#ResearchExcellence #CredibleResearch
#earlycareerresearcher
Join an incredible line-up of speakers next month to explore how credible research is applied across academia, industry, biotech, and clinical trials.
Register now: bna.org.uk/events/ems-e...
#ResearchExcellence #CredibleResearch
#earlycareerresearcher
January 14, 2026 at 2:46 PM
This looks like a fantastic event, with @britishneuro.bsky.social continuing to drive improvements in the credibility of #neuroscience research 🧠
And it is FREE for #BNA members!!!
And it is FREE for #BNA members!!!
Reposted by Prof Anthony Isles
Some exciting books coming out this year (brief thread):
The brilliant @jomarchant.bsky.social looks at the science of now and the nature of reality: In Search of Now
The brilliant @jomarchant.bsky.social looks at the science of now and the nature of reality: In Search of Now
January 14, 2026 at 12:54 PM
Some exciting books coming out this year (brief thread):
The brilliant @jomarchant.bsky.social looks at the science of now and the nature of reality: In Search of Now
The brilliant @jomarchant.bsky.social looks at the science of now and the nature of reality: In Search of Now
Reposted by Prof Anthony Isles
The National Mouse Genetics Network has contributed to a new briefing from the UK Parliamentary Office of Science and Technology (POST) that examines the development and use of emerging technologies as alternatives to animals in life sciences research.
nmgn.mrc.ukri.org/news/mary-ly...
nmgn.mrc.ukri.org/news/mary-ly...
Mary Lyon Centre and National Mouse Genetics Network contribute to Parliamentary report on research models | National Mouse Genetics Network
The UK Parliamentary Office of Science and Technology (POST) has published a new briefing examining the development and use of emerging technologies as alternatives to animals in life sciences researc...
nmgn.mrc.ukri.org
January 13, 2026 at 10:08 AM
The National Mouse Genetics Network has contributed to a new briefing from the UK Parliamentary Office of Science and Technology (POST) that examines the development and use of emerging technologies as alternatives to animals in life sciences research.
nmgn.mrc.ukri.org/news/mary-ly...
nmgn.mrc.ukri.org/news/mary-ly...
The deadline to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social is rapidly approaching!
➡️ 18th January 2026 ⬅️
➡️ 18th January 2026 ⬅️
📢 Job Alert 📢
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Senior Research Associate at Lancaster University
An opportunity for an academic position as a Senior Research Associate is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
January 12, 2026 at 1:17 PM
The deadline to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social is rapidly approaching!
➡️ 18th January 2026 ⬅️
➡️ 18th January 2026 ⬅️
Reposted by Prof Anthony Isles
‘At the edge of the mere’
Artist: CF Tunnicliffe
(What to Look for in Winter, 1959)
Artist: CF Tunnicliffe
(What to Look for in Winter, 1959)
January 11, 2026 at 8:21 AM
‘At the edge of the mere’
Artist: CF Tunnicliffe
(What to Look for in Winter, 1959)
Artist: CF Tunnicliffe
(What to Look for in Winter, 1959)
Reposted by Prof Anthony Isles
Into The Woods. -1°C just after dawn. Pheasants.
January 10, 2026 at 9:18 AM
Into The Woods. -1°C just after dawn. Pheasants.
UK bee & pollinator populations are dropping. This is partly due to how many pesticides we use - it doesn’t have to be this way. France has banned pesticides from towns & cities. Tell the UK Government to follow in their footsteps & protect our pollinators:
action.greenpeace.org.uk/save-the-bees
action.greenpeace.org.uk/save-the-bees
ACTION: Sign the petition and tell the UK government to protect our pollinators.
The UK’s pollinator numbers are dropping heavily - we need the UK government to step in and protect them.
action.greenpeace.org.uk
January 10, 2026 at 1:17 PM
UK bee & pollinator populations are dropping. This is partly due to how many pesticides we use - it doesn’t have to be this way. France has banned pesticides from towns & cities. Tell the UK Government to follow in their footsteps & protect our pollinators:
action.greenpeace.org.uk/save-the-bees
action.greenpeace.org.uk/save-the-bees
Reposted by Prof Anthony Isles
“What the hell kind of Christian is this guy anyway?”
From the new Private Eye, out now.
From the new Private Eye, out now.
January 9, 2026 at 6:11 PM
“What the hell kind of Christian is this guy anyway?”
From the new Private Eye, out now.
From the new Private Eye, out now.
Reposted by Prof Anthony Isles
Number crunching: Pay and dividends of Bet365 chief executive v total fiscal cost of gambling-related harm.
From the new Private Eye, out now.
From the new Private Eye, out now.
January 9, 2026 at 12:14 PM
Number crunching: Pay and dividends of Bet365 chief executive v total fiscal cost of gambling-related harm.
From the new Private Eye, out now.
From the new Private Eye, out now.
Reposted by Prof Anthony Isles
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session.
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
January 9, 2026 at 10:54 AM
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session.
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Reposted by Prof Anthony Isles
10 days left to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
🧠🧬🐭
🧠🧬🐭
📢 Job Alert 📢
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Senior Research Associate at Lancaster University
An opportunity for an academic position as a Senior Research Associate is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
January 8, 2026 at 8:13 AM
10 days left to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
🧠🧬🐭
🧠🧬🐭
Reposted by Prof Anthony Isles
I have not personally used X/Twitter for some time now. It was already an unpleasant place prior to its takeover by Elon Musk but since his acceptance of hate speech and anonymous online abusers, it has become utterly unusable.
January 8, 2026 at 12:31 PM
I have not personally used X/Twitter for some time now. It was already an unpleasant place prior to its takeover by Elon Musk but since his acceptance of hate speech and anonymous online abusers, it has become utterly unusable.
Reposted by Prof Anthony Isles
Other work of the Ladybird artists.
‘Winter Landscape’
Artist: Rowland Hilder
‘Winter Landscape’
Artist: Rowland Hilder
January 8, 2026 at 7:56 AM
Other work of the Ladybird artists.
‘Winter Landscape’
Artist: Rowland Hilder
‘Winter Landscape’
Artist: Rowland Hilder
10 days left to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
🧠🧬🐭
🧠🧬🐭
📢 Job Alert 📢
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Senior Research Associate at Lancaster University
An opportunity for an academic position as a Senior Research Associate is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
January 8, 2026 at 8:13 AM
10 days left to apply for this position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
🧠🧬🐭
🧠🧬🐭
Reposted by Prof Anthony Isles
Cleared my head with a 🏃 in the ☀️ this morning 😊
Hopefully this will brighten your timeline a little…
Hopefully this will brighten your timeline a little…
January 7, 2026 at 1:52 PM
Cleared my head with a 🏃 in the ☀️ this morning 😊
Hopefully this will brighten your timeline a little…
Hopefully this will brighten your timeline a little…
Reposted by Prof Anthony Isles
Northern hemisphere people! Can someone explain #DryJanuary to me? Why do you choose to forgo booze in the coldest, most miserable month of the year? Sounds like bad planning.
January 7, 2026 at 3:44 PM
Northern hemisphere people! Can someone explain #DryJanuary to me? Why do you choose to forgo booze in the coldest, most miserable month of the year? Sounds like bad planning.
Reposted by Prof Anthony Isles
Absolutely fucking tremendous from the FT.
Who’s who at X, the deepfake porn site formerly known as Twitter
A look inside Elon Musk’s big tent
www.ft.com
January 6, 2026 at 4:53 PM
Absolutely fucking tremendous from the FT.
Reposted by Prof Anthony Isles
Other work by the Ladybird artists
‘January’ Shell Guide
Artist: SR Badmin
‘January’ Shell Guide
Artist: SR Badmin
January 5, 2026 at 7:59 PM
Other work by the Ladybird artists
‘January’ Shell Guide
Artist: SR Badmin
‘January’ Shell Guide
Artist: SR Badmin
Cleared my head with a 🏃 in the ☀️ this morning 😊
Hopefully this will brighten your timeline a little…
Hopefully this will brighten your timeline a little…
January 7, 2026 at 1:52 PM
Cleared my head with a 🏃 in the ☀️ this morning 😊
Hopefully this will brighten your timeline a little…
Hopefully this will brighten your timeline a little…
Reposted by Prof Anthony Isles
Check out our new manuscript describing the circuit-specific impact of 16p11.2, a chromosomal region linked to neurodevelopmental disorders! @UIowaNeuro @IowaNeuroPharm @Hawk_IDDRC
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 5, 2026 at 8:00 PM
Check out our new manuscript describing the circuit-specific impact of 16p11.2, a chromosomal region linked to neurodevelopmental disorders! @UIowaNeuro @IowaNeuroPharm @Hawk_IDDRC
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Prof Anthony Isles
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers
The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...
www.biorxiv.org
January 5, 2026 at 12:51 PM
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
Reposted by Prof Anthony Isles
That back-to-work feeling
Artist: Eric Winter
Jack and the Beanstalk, 1965
Artist: Eric Winter
Jack and the Beanstalk, 1965
January 5, 2026 at 8:10 AM
That back-to-work feeling
Artist: Eric Winter
Jack and the Beanstalk, 1965
Artist: Eric Winter
Jack and the Beanstalk, 1965
Reposted by Prof Anthony Isles
We are hiring a Biological Samples Shipping Coordinator to coordinate the export of biological materials to the scientific community around the world.
Apply by 11th January
Apply by 11th January
Biological Samples Shipping Coordinator - MLC 2758 - Medical Research Council
Location: Harwell Campus, Oxfordshire. Vacancy: Biological Samples Shipping Coordinator - MLC 2758. Closing Date: 11/01/2026, 23:55
mrc.tal.net
January 5, 2026 at 8:30 AM
We are hiring a Biological Samples Shipping Coordinator to coordinate the export of biological materials to the scientific community around the world.
Apply by 11th January
Apply by 11th January