prot_papers
@protpapers.bsky.social
🤖 Feed for papers about HLA/MHC neoantigens, immunopeptidomes and HDX-MS from PubMed and bioRxiv. Run by @ab604.uk inspired by @phypapers.bsky.social and https://bsky.app/profile/r-bloggers.bsky.social. Code: https://github.com/ab604/prot-paper-bot
Neoepitopes at the crossroads of immunometabolism: metabolic remodeling of antigen presentation in type 1 diabetes https://pubmed.ncbi.nlm.nih.gov/41694397/
February 16, 2026 at 5:59 PM
Neoepitopes at the crossroads of immunometabolism: metabolic remodeling of antigen presentation in type 1 diabetes https://pubmed.ncbi.nlm.nih.gov/41694397/
Solvent Isotope Effect on the Stability of a Heterodimeric Protein
https://www.biorxiv.org/content/10.64898/2026.02.12.705670v1
February 15, 2026 at 6:11 AM
Solvent Isotope Effect on the Stability of a Heterodimeric Protein
https://www.biorxiv.org/content/10.64898/2026.02.12.705670v1
How the non-motile kinesin KIF7 adapts conserved kinesin principles for itsfunction in Hedgehog signaling
https://www.biorxiv.org/content/10.64898/2026.02.06.704517v1
February 10, 2026 at 6:16 PM
How the non-motile kinesin KIF7 adapts conserved kinesin principles for itsfunction in Hedgehog signaling
https://www.biorxiv.org/content/10.64898/2026.02.06.704517v1
Characterization of a novel soluble melanin secreted by Gliomastix polychroma
https://www.biorxiv.org/content/10.64898/2026.02.06.704125v1
February 10, 2026 at 6:39 AM
Characterization of a novel soluble melanin secreted by Gliomastix polychroma
https://www.biorxiv.org/content/10.64898/2026.02.06.704125v1
Targeting collagen biosynthesis by small molecules inhibiting the function of the peptide-substrate-binding domain of collagen prolyl 4-hydroxylases
https://www.biorxiv.org/content/10.64898/2026.02.05.703963v1
February 8, 2026 at 6:10 AM
Targeting collagen biosynthesis by small molecules inhibiting the function of the peptide-substrate-binding domain of collagen prolyl 4-hydroxylases
https://www.biorxiv.org/content/10.64898/2026.02.05.703963v1
Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG) https://pubmed.ncbi.nlm.nih.gov/41643293/
February 6, 2026 at 6:11 AM
Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG) https://pubmed.ncbi.nlm.nih.gov/41643293/
DIA-MS based plasma peptidomic workflow for profiling organ-derived peptides
https://www.biorxiv.org/content/10.64898/2026.02.02.703436v1
February 5, 2026 at 6:10 PM
DIA-MS based plasma peptidomic workflow for profiling organ-derived peptides
https://www.biorxiv.org/content/10.64898/2026.02.02.703436v1
Degradation Determinants Are Abundant in Human Noncanonical Proteins and Minor Annotated Isoforms https://pubmed.ncbi.nlm.nih.gov/41549067/
February 3, 2026 at 6:10 AM
Degradation Determinants Are Abundant in Human Noncanonical Proteins and Minor Annotated Isoforms https://pubmed.ncbi.nlm.nih.gov/41549067/
Nano-scaled, fully automated hydrogen/deuterium exchange for analysis of macromolecular assemblies reaching the MDa scale https://pubmed.ncbi.nlm.nih.gov/41617135/
January 31, 2026 at 5:46 PM
Nano-scaled, fully automated hydrogen/deuterium exchange for analysis of macromolecular assemblies reaching the MDa scale https://pubmed.ncbi.nlm.nih.gov/41617135/
HLA-DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate-Pulsing https://pubmed.ncbi.nlm.nih.gov/41607090/
January 29, 2026 at 5:57 PM
HLA-DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate-Pulsing https://pubmed.ncbi.nlm.nih.gov/41607090/
Mapping SARS-CoV-2 Nucleocapsid Function with Nanobodies
https://www.biorxiv.org/content/10.64898/2026.01.26.701894v1
January 28, 2026 at 5:50 AM
Mapping SARS-CoV-2 Nucleocapsid Function with Nanobodies
https://www.biorxiv.org/content/10.64898/2026.01.26.701894v1
Immunopeptidomics reveals peptide antigens preferentially presented in psoriasis lesional skin of HLA-C*06:02 carriers
https://www.biorxiv.org/content/10.64898/2026.01.24.701535v1
January 27, 2026 at 5:48 AM
Immunopeptidomics reveals peptide antigens preferentially presented in psoriasis lesional skin of HLA-C*06:02 carriers
https://www.biorxiv.org/content/10.64898/2026.01.24.701535v1
MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation https://pubmed.ncbi.nlm.nih.gov/41571884/
January 23, 2026 at 5:48 AM
MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation https://pubmed.ncbi.nlm.nih.gov/41571884/
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome https://pubmed.ncbi.nlm.nih.gov/41566667/
January 22, 2026 at 5:49 PM
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome https://pubmed.ncbi.nlm.nih.gov/41566667/
Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics https://pubmed.ncbi.nlm.nih.gov/41559053/
January 22, 2026 at 5:50 AM
Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics https://pubmed.ncbi.nlm.nih.gov/41559053/
Immunopathogenic role of the HLA-B51:01-specific immunopeptidome in Behcet's disease https://pubmed.ncbi.nlm.nih.gov/41558215/
January 21, 2026 at 6:09 PM
Immunopathogenic role of the HLA-B51:01-specific immunopeptidome in Behcet's disease https://pubmed.ncbi.nlm.nih.gov/41558215/
Degradation determinants are abundant in human noncanonical proteins and minor annotated isoforms https://pubmed.ncbi.nlm.nih.gov/41549067/
January 19, 2026 at 5:44 PM
Degradation determinants are abundant in human noncanonical proteins and minor annotated isoforms https://pubmed.ncbi.nlm.nih.gov/41549067/
Coxsackievirus B Escapes Antiviral CD8⁺ T Cells but Triggers Robust CD4⁺ Memory Responses
https://www.biorxiv.org/content/10.64898/2026.01.16.699852v1
January 18, 2026 at 5:44 AM
Coxsackievirus B Escapes Antiviral CD8⁺ T Cells but Triggers Robust CD4⁺ Memory Responses
https://www.biorxiv.org/content/10.64898/2026.01.16.699852v1
NetMHCIIphosPan: a machine learning tool for predicting HLA class II antigen presentation of phosphorylated peptides https://pubmed.ncbi.nlm.nih.gov/41542563/
January 17, 2026 at 5:35 PM
NetMHCIIphosPan: a machine learning tool for predicting HLA class II antigen presentation of phosphorylated peptides https://pubmed.ncbi.nlm.nih.gov/41542563/
A transgenic mouse allows characterization of the HLA-C06:02 immunopeptidome in a model of psoriasis https://pubmed.ncbi.nlm.nih.gov/41453599/
January 17, 2026 at 5:41 AM
A transgenic mouse allows characterization of the HLA-C06:02 immunopeptidome in a model of psoriasis https://pubmed.ncbi.nlm.nih.gov/41453599/
EBV infection and HLA-DR15 jointly drive multiple sclerosis by myelin peptide presentation https://pubmed.ncbi.nlm.nih.gov/41534530/
January 16, 2026 at 5:46 AM
EBV infection and HLA-DR15 jointly drive multiple sclerosis by myelin peptide presentation https://pubmed.ncbi.nlm.nih.gov/41534530/
quantms-rescoring enables deep proteome coverage across protein quantification, immunopeptidomics, and post-translational modifications experiments.
https://www.biorxiv.org/content/10.64898/2026.01.12.698877v1
January 13, 2026 at 5:48 PM
quantms-rescoring enables deep proteome coverage across protein quantification, immunopeptidomics, and post-translational modifications experiments.
https://www.biorxiv.org/content/10.64898/2026.01.12.698877v1
Hydrogen/deuterium exchange mass spectrometry analysis of ribosome-nascent chain complexes to study protein biogenesis at the peptide level https://pubmed.ncbi.nlm.nih.gov/41526491/
January 13, 2026 at 5:46 AM
Hydrogen/deuterium exchange mass spectrometry analysis of ribosome-nascent chain complexes to study protein biogenesis at the peptide level https://pubmed.ncbi.nlm.nih.gov/41526491/
Small molecule stabilization of diverse amyloidogenic immunoglobulin light chains revealed by hydrogen-deuterium exchange mass spectrometry
https://www.biorxiv.org/content/10.64898/2026.01.07.698275v1
January 10, 2026 at 5:36 PM
Small molecule stabilization of diverse amyloidogenic immunoglobulin light chains revealed by hydrogen-deuterium exchange mass spectrometry
https://www.biorxiv.org/content/10.64898/2026.01.07.698275v1
Peptidomics Mapping of Proteolysis Highlights Triple Activation of Sprouted Seeds by Germination, Homogenisation and Species Mixture.
https://www.biorxiv.org/content/10.64898/2026.01.08.698447v1
January 10, 2026 at 5:42 AM
Peptidomics Mapping of Proteolysis Highlights Triple Activation of Sprouted Seeds by Germination, Homogenisation and Species Mixture.
https://www.biorxiv.org/content/10.64898/2026.01.08.698447v1