James Murphy
@pseudokinase.bsky.social
Cell signaling, kinases, MLKL and other zombie proteins. NHMRC Leadership Fellow, Professor and Deputy Director at WEHI, Melbourne. He/him. Views my own
Reposted by James Murphy
Jane Richardson was born #OTD in 1941
+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012
#WomenInSTEM
+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012
#WomenInSTEM
January 26, 2026 at 12:06 AM
Jane Richardson was born #OTD in 1941
+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012
#WomenInSTEM
+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012
#WomenInSTEM
Reposted by James Murphy
#NARF is on bluesky! 👉 if you’ve held a fellowship in the last 10 years, you should join.
The Australian Biomedical Research sector is in crisis due to years of chronic underfunding. We recently asked Australian researchers how they felt about their career prospects. This is a word cloud based on their responses 😢🧪
January 25, 2026 at 1:52 AM
#NARF is on bluesky! 👉 if you’ve held a fellowship in the last 10 years, you should join.
Reposted by James Murphy
Check out the latest issue of Biochemical Journal, featuring research on enzymology, molecular interactions, signaling biotechnology, gene expression, host-microbe interactions, and mutation🧪 https://ow.ly/MijF50XXQtp
January 17, 2026 at 10:30 AM
Check out the latest issue of Biochemical Journal, featuring research on enzymology, molecular interactions, signaling biotechnology, gene expression, host-microbe interactions, and mutation🧪 https://ow.ly/MijF50XXQtp
Reposted by James Murphy
In the words of a world-renowned cardiologist, Australia’s young medical researchers are “left to flounder with total job insecurity and family pressures. It’s the best recipe we have for raiding our future, in terms of a medical research workforce and the benefits of medical research”
‘We’re losing careers’: Leading cardiologist warns Australian medical research is in crisis
The head of the Heart Research Institute is telling young scientists medical research is a “terrible career path”. There’s a $5 billion answer in the government’s budget.
www.theage.com.au
January 16, 2026 at 10:27 PM
In the words of a world-renowned cardiologist, Australia’s young medical researchers are “left to flounder with total job insecurity and family pressures. It’s the best recipe we have for raiding our future, in terms of a medical research workforce and the benefits of medical research”
Reposted by James Murphy
🎉 Happy New Year! I am so excited for #TIBS50!
✍️ My editorial provides insights into the exciting projects planned for 2026, and I hope that each of you finds something that resonates with you. Please reach out to share your ideas for content as well as your #ScienceSketch ideas!
✍️ My editorial provides insights into the exciting projects planned for 2026, and I hope that each of you finds something that resonates with you. Please reach out to share your ideas for content as well as your #ScienceSketch ideas!
🎉 It's here! Our January issue has dropped and, with it, the start of our hashtag#TIBS50 anniversary celebration! Dive into the full issue and join us as we honor five decades of publishing 👉 www.cell.com/trends/bioch...
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January 15, 2026 at 4:35 PM
🎉 Happy New Year! I am so excited for #TIBS50!
✍️ My editorial provides insights into the exciting projects planned for 2026, and I hope that each of you finds something that resonates with you. Please reach out to share your ideas for content as well as your #ScienceSketch ideas!
✍️ My editorial provides insights into the exciting projects planned for 2026, and I hope that each of you finds something that resonates with you. Please reach out to share your ideas for content as well as your #ScienceSketch ideas!
Reposted by James Murphy
Interested in writing for a wide, interdisciplinary audience? The Biochemist has announced its themed issues for 2026, if your work aligns with any of these themes - get in touch with our Editorial Team today! 🧪 https://ow.ly/f2cT50XWyov
January 15, 2026 at 11:00 AM
Interested in writing for a wide, interdisciplinary audience? The Biochemist has announced its themed issues for 2026, if your work aligns with any of these themes - get in touch with our Editorial Team today! 🧪 https://ow.ly/f2cT50XWyov
Reposted by James Murphy
💡Solving decades-long mysteries with cryoEM. 💥Brilliant science + best tech = life-saving medical research. Shaping the future of health through bold new approaches.
#ParkinsonsDisease
#ParkinsonsDisease
January 15, 2026 at 12:35 AM
💡Solving decades-long mysteries with cryoEM. 💥Brilliant science + best tech = life-saving medical research. Shaping the future of health through bold new approaches.
#ParkinsonsDisease
#ParkinsonsDisease
Reposted by James Murphy
Pseudokinases have emerged as key regulators of numerous fundamental biological processes however, bacterial pseudokinases remain largely unexplored. O’Boyle et al reveal understudied bacterial serine–threonine pseudokinase families in this mini-review. https://doi.org/10.1042/BST20253080
January 8, 2026 at 10:00 AM
Pseudokinases have emerged as key regulators of numerous fundamental biological processes however, bacterial pseudokinases remain largely unexplored. O’Boyle et al reveal understudied bacterial serine–threonine pseudokinase families in this mini-review. https://doi.org/10.1042/BST20253080
Reposted by James Murphy
Lorne Proteins 2026 🏖️ features Princeton University protein cognoscenti Michael Hecht, designing an artificial proteome with new folds and functions; and Jerelle Joseph, on tractable MD simulations of multiprotein condensates & synthetic condensate engineering.
🔗 Register now www.lorneproteins.org
🔗 Register now www.lorneproteins.org
January 6, 2026 at 11:51 PM
Lorne Proteins 2026 🏖️ features Princeton University protein cognoscenti Michael Hecht, designing an artificial proteome with new folds and functions; and Jerelle Joseph, on tractable MD simulations of multiprotein condensates & synthetic condensate engineering.
🔗 Register now www.lorneproteins.org
🔗 Register now www.lorneproteins.org
Reposted by James Murphy
Unsure how to gain your first peer review opportunity, or keen to improve your feedback? Catch up on our latest ECR webinar and gain practical tips from Biochemical Society Editors-in-Chief on writing and submitting a high-quality review!🧪 https://ow.ly/5pWZ50XNBJs
January 2, 2026 at 12:45 PM
Unsure how to gain your first peer review opportunity, or keen to improve your feedback? Catch up on our latest ECR webinar and gain practical tips from Biochemical Society Editors-in-Chief on writing and submitting a high-quality review!🧪 https://ow.ly/5pWZ50XNBJs
Reposted by James Murphy
Working with a great team to organize @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March! Join us to explore emerging research in Banff! keysym.us/KSInnateImmune26 #KSInnateImmune26
Innate Immunity: Diversity in Host Defense and Disease | Keystone Symposia
Join us at the Keystone Symposia on Innate Immunity: Diversity in Host Defense and Disease, March 2026, in Banff, with field leaders!
keysym.us
January 1, 2026 at 11:22 PM
Working with a great team to organize @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March! Join us to explore emerging research in Banff! keysym.us/KSInnateImmune26 #KSInnateImmune26
I occasionally enjoy a game of NFL especially when cricket tests go for only 2 days in these uncertain times. But my sense is that it’s like publishing a paper - the last 10% takes 90% of the time #academicsky
December 29, 2025 at 4:39 AM
I occasionally enjoy a game of NFL especially when cricket tests go for only 2 days in these uncertain times. But my sense is that it’s like publishing a paper - the last 10% takes 90% of the time #academicsky
Reposted by James Murphy
Pssst! I have a PhD position available. Please pass it on
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Exploring Resistance to KRAS inhibitors (KRASi) of differentiated Mechanism of Action at Babraham Institute (Cambridge) on FindAPhD.com
PhD Project - Exploring Resistance to KRAS inhibitors (KRASi) of differentiated Mechanism of Action at Babraham Institute (Cambridge), listed on FindAPhD.com
www.findaphd.com
December 28, 2025 at 6:18 PM
Pssst! I have a PhD position available. Please pass it on
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Who’s ready for hot cross buns?
December 29, 2025 at 3:46 AM
Who’s ready for hot cross buns?
I totally failed to photograph it but I made what might now be a post Xmas tradition. Pizza, cranberry sauce base, turkey (and stuffing) cubed on top with Brie and mozzarella. No complaints from the masses #leftovers
December 28, 2025 at 7:34 AM
I totally failed to photograph it but I made what might now be a post Xmas tradition. Pizza, cranberry sauce base, turkey (and stuffing) cubed on top with Brie and mozzarella. No complaints from the masses #leftovers
Reposted by James Murphy
Medical research matters!
Australian scientists are making potentially lifesaving breakthroughs into the molecular mechanisms of brain tumours - discoveries with potential for commercialisation and global uptake. We should support them better via the MRFF and NHMRC.
Australian scientists are making potentially lifesaving breakthroughs into the molecular mechanisms of brain tumours - discoveries with potential for commercialisation and global uptake. We should support them better via the MRFF and NHMRC.
Mark’s deadly cancer will come back. Now scientists know why
When Mark Norris finished his cancer treatment, there was nothing doctors could do except wait for it to return. The father of two says that’s not good enough.
www.theage.com.au
December 28, 2025 at 5:35 AM
Medical research matters!
Australian scientists are making potentially lifesaving breakthroughs into the molecular mechanisms of brain tumours - discoveries with potential for commercialisation and global uptake. We should support them better via the MRFF and NHMRC.
Australian scientists are making potentially lifesaving breakthroughs into the molecular mechanisms of brain tumours - discoveries with potential for commercialisation and global uptake. We should support them better via the MRFF and NHMRC.
Reposted by James Murphy
So 2025 turned out to be a big year for de novo antibody design! Here are thoughts and predictions on the state of de novo antibody design heading into 2026 🧵
December 26, 2025 at 11:49 PM
So 2025 turned out to be a big year for de novo antibody design! Here are thoughts and predictions on the state of de novo antibody design heading into 2026 🧵
Reposted by James Murphy
Lorne Proteins 2026 🏖️🤩 Featuring speakers Elitza Tocheva, UBC, on outer spore membrane biogenesis for endospore formation in Firmicutes; and EMBO keynote speaker David Drew, Stockholm University, focusing on GLUT glucose transporters and Na⁺/H⁺ exchangers.
🔗 Register now at: www.lorneproteins.org
🔗 Register now at: www.lorneproteins.org
December 23, 2025 at 10:16 PM
Lorne Proteins 2026 🏖️🤩 Featuring speakers Elitza Tocheva, UBC, on outer spore membrane biogenesis for endospore formation in Firmicutes; and EMBO keynote speaker David Drew, Stockholm University, focusing on GLUT glucose transporters and Na⁺/H⁺ exchangers.
🔗 Register now at: www.lorneproteins.org
🔗 Register now at: www.lorneproteins.org
An unexpectedly vibrant live music scene in Canberra. Very much hoping to run into Sir Paul and to hear him sing about his mini horse called Jet. Imagine the pressure on the Friday and Saturday acts?!
December 20, 2025 at 4:25 AM
An unexpectedly vibrant live music scene in Canberra. Very much hoping to run into Sir Paul and to hear him sing about his mini horse called Jet. Imagine the pressure on the Friday and Saturday acts?!
Reposted by James Murphy
The great news for me is that it’s Saturday in Australia so the chances of even more editor and reviewer assignments have plummeted for at least 2 days. I’m hoping everyone will be as kind to my year end submissions
December 13, 2025 at 4:45 AM
The great news for me is that it’s Saturday in Australia so the chances of even more editor and reviewer assignments have plummeted for at least 2 days. I’m hoping everyone will be as kind to my year end submissions
Every July and August, us good folks in the southern hemisphere review our little hearts out to pick up the slack for the “sorry I’m travelling” crowd up north. Guess what Santa’s bringing our northern friends for the festive season?! Peer review requests!
December 9, 2025 at 9:45 AM
Every July and August, us good folks in the southern hemisphere review our little hearts out to pick up the slack for the “sorry I’m travelling” crowd up north. Guess what Santa’s bringing our northern friends for the festive season?! Peer review requests!
Reposted by James Murphy
📢 Lorne Proteins 2026 features Ruchi Anand, IIT Bombay—applying advanced structural biology to AMR mechanisms 🦠and biosensor development 💡. And synthetic biology titan Hagan Bayley, Oxford, fabricating 3D tissues 🧫 to founding Oxford Nanopore 🍩.
🤓 Register now at: www.lorneproteins.org
🤓 Register now at: www.lorneproteins.org
December 5, 2025 at 1:51 AM
📢 Lorne Proteins 2026 features Ruchi Anand, IIT Bombay—applying advanced structural biology to AMR mechanisms 🦠and biosensor development 💡. And synthetic biology titan Hagan Bayley, Oxford, fabricating 3D tissues 🧫 to founding Oxford Nanopore 🍩.
🤓 Register now at: www.lorneproteins.org
🤓 Register now at: www.lorneproteins.org
Reposted by James Murphy
@ginaravenscroft.bsky.social & #NARF are collecting impact statements from Australian researchers
‘ Please consider sharing your story about the impact of Australia's chronic underfunding of science and biomedical research.’
lnkd.in/g8A_PAZG
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‘ Please consider sharing your story about the impact of Australia's chronic underfunding of science and biomedical research.’
lnkd.in/g8A_PAZG
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December 1, 2025 at 10:49 PM
@ginaravenscroft.bsky.social & #NARF are collecting impact statements from Australian researchers
‘ Please consider sharing your story about the impact of Australia's chronic underfunding of science and biomedical research.’
lnkd.in/g8A_PAZG
1/
‘ Please consider sharing your story about the impact of Australia's chronic underfunding of science and biomedical research.’
lnkd.in/g8A_PAZG
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Reposted by James Murphy
December 2, 2025 at 8:48 AM