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Reposted

Wilco Kwanten @kvvanten.bsky.social · May 13

In the (early) pathophysiology of MASLD the LSEC and microvascular alterations are key. Lanifibranor improves LSEC capillarisation and dysfunction! tinyurl.com/x37637j4
#AntwerpHepatology #AntwerpHypothesis @rautoupe.bsky.social @svenfrancque.bsky.social

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 10

Is the etiological work-up of #PSVD a one-size-fits-all?

DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease".

#EASLCongress #EASL2025 #LiverResearch
@easlnews.bsky.social

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Reposted

mattiasmandorfer.bsky.social @mattiasmandorfer.bsky.social · May 10

📢 First @easlnews.bsky.social CPG on surgery in cirrhosis presented today together with the one on TIPS!
🤝 See you at 10:30 Erlinger Room!
@bavenocoop.bsky.social #LiverSky

Journal of Hepatology @jhepatology.bsky.social · May 10

🆕CPG in press❕

EASL Clinical Practice Guidelines on extrahepatic abdominal surgery in patients with cirrhosis and advanced chronic liver disease

Find it here👉https://bit.ly/3GM9EEB

#LiverSky
@easlnews.bsky.social

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 10

Estefania Huergo presents methylation data in AD patients, selected as best Young Investigator abstract in Basic Science at #EASL2025 - Congrats! 🎉
@navarrabiomed.bsky.social
@easlnews.bsky.social
#Epigenetics #LiverResearch

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 10

Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk.

@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social

#Cirrhosis #ACLF #EASL2025"

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 10

❤️ Cardiac performance is impaired in patients with proven alcohol-related hepatitis and predicts 3-month mortality in this patient population

#POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF)

📅 Presented at the #EASLCongress | #EASL2025
@easlnews.bsky.social

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 9

How do you build&lead a successful research team?
The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team.
@inserm.fr #EASL2025

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 9

Greetings from the DECISION Investigator Meeting at #EASL2025: Study updates and collaborative discussions with Paolo Caraceni & @rautoupe.bsky.social

#ClinicalTrials #cirrhosis

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 9

Good morning!
DECISION coordinator Pierre-Emmanuel Rautou just started the early morning abstract session on #cirrhosis at the #EASLCongress in Amsterdam. You can still join in the Benhamou Room until 09.45am! @easlnews.bsky.social

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 9

Next at the DECISION Networking Session at #EASL2025, Theresa Wirtz (UKA) presents scRNA-seq data showing a monocyte subset linked to ACLF risk.
Fascinating translational science in action!
@brunslab.bsky.social ky.social @easlnews.bsky.social ky.social

#scRNAseq #ACLF

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 9

Lastly at DECISION's Networking Session, Richard Moreau shares new data: high-throughput omics reveals biomarkers for infection & poor outcomes in cirrhosis.
@inserm.fr @easlnews.bsky.social sky.social

#Metabolomics #Cytokinomics #EASL2025

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Reposted

rautoupe.bsky.social @rautoupe.bsky.social · Mar 15

📢📢 looking for a co-founder (CEO) for an early stage medtech startup‼️

Our goal: bring extracellular vesicles from the lab to the bedside of patients with chronic liver disease.🧪

Find the offer here: www.lesdeeptech.fr/tandem/41693...

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Reposted

DECISION Horizon2020 @decision4liver.bsky.social · May 9

Kicking off our #EASL2025 Networking Session with an intro to the DECISION project by coordinator Pierre-Emmanuel Rautou - Let’s talk systems medicine, cirrhosis, and precision care! @rautoupe.bsky.social pe.bsky.social @easlnews.bsky.social ky.social #LiverDisease

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rautoupe.bsky.social @rautoupe.bsky.social · Mar 21

Interested in vascular liver diseases and more broadly in liver and vessels?
▶️Join the COST Action EURO-VALDI-NET: www.cost.eu/actions/CA23...

Eligibility criteria there: www.cost.eu/am-i-eligible/

European vascular liver diseases network

Vascular liver diseases are a heterogeneous group of rare disorders characterized by an impaired vascular flow in the splanchnic and/or intrahepatic vasculature. They mainly include recent portal...

www.cost.eu

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rautoupe.bsky.social @rautoupe.bsky.social · Mar 15

📢📢 looking for a co-founder (CEO) for an early stage medtech startup‼️

Our goal: bring extracellular vesicles from the lab to the bedside of patients with chronic liver disease.🧪

Find the offer here: www.lesdeeptech.fr/tandem/41693...

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rautoupe.bsky.social @rautoupe.bsky.social · Feb 22

📢📢 Analysis of 249 patients with MASLD and of 2 rat models:
⚠️Liver endothelial cell (LSEC) capillarisation appears before MASH onset
❌LSEC capillarisation progresses with liver fibrosis and inflammation
✅Lanifibranor improves LSEC function

authors.elsevier.com/sd/article/S...

rautoupe.bsky.social @rautoupe.bsky.social · Feb 18

Tips for managing invasive procedures in patients with cirrhosis 🩸🩸:
➡️What limits of laboratory values❓
➡️How to risk stratify procedures❓
➡️When to stop and restart anticoagulants and antiplatelet agents❓
Find this and more there:
doi.org/10.3350/cmh....

rautoupe.bsky.social @rautoupe.bsky.social · Feb 8

📢📢Interested in vascular liver diseases❓
Check the opportunities for:
✅Short Term Scientific Mission 🧳
Deadline Feb 21
✅Conference Grants
Deadline March 14

➡️ more details there
www.valdig.eu/cost-action-...

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Reposted

Rui Castro @ruicastrohd.bsky.social · Jan 24

@rautoupe.bsky.social provides an update on endothelium-platelet interactions in SLD:

🎯 LSEC capillarisation increases with liver fibrosis in MASLD
🎯 Aspirin improves MASLD
🎯 Likely by inhibiting platelet accumulation and/or platelet EV release

@easlnews.bsky.social #SLDSummit