Sara McArdle
@saramcardle.bsky.social
Staff Scientist at the La Jolla Institute Microscopy and Histology Facility. I love cat videos and microscopy images and I believe that Matlab is better than Python :)
Reposted by Sara McArdle
![Comic. Panels up to the 10-year point are grayed out. New panels since the Ten Years comic, which chronicles the first ten years of PERSON 1's journey with cancer: (1) [two people in bed] PERSON 1 (woman): One more chapter? PERSON 2 (man): Don’t we both have to get up early? PERSON 1: Nnnnnggggh PERSON 2: Sure, good point. (2) [many people wearing masks, walking while looking at graphs on their phones] (3) [birds landing on people] PERSON 2 in beanie and scarf: Hah! They like *my* seeds best. PERSON 1 in scarf holding phone with a bird sitting on it: Wait, how do I take a picture of this one? (4) [two people rowing boats with tree landscape] (5) [Person 1 carries overflowing stack of things to Person 2 in bed] PERSON 1: I brought you honey lemon tea, more pillows, a cinnamon roll, Tylenol, another blanket, a– PERSON 2: It was just Appendicitis, I’m really– PERSON 1: *It is my turn to take care of you and I am going to do it right!* (6) [Two people in car] (7) [still in car) PERSON 1: Oh my god. PERSON 2: Oh my god. (8) [car driving] PERSON 1: Pull over! PERSON 2: I am! (9) [both people get out of car] (10) [Large colored panel of aurora borealis over water with both people looking on] (11) [Person 1 sits against tree while Person 2 lies on the ground] PERSON 1: Fifteen years. No sign of the cancer. (12) I *am* having some weird symptoms. Joint pain. Fatigue. I think I’m losing my close-up vision. PERSON 2: Yeah. Me too. (13) PERSON 2: I think we’re getting old. (14) PERSON 1: I guess that’s okay. PERSON 2: It’s all I wanted.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreihwhjblp5lyiwp63ouar7ocfea7evmckytoeo7rkfuoo4gw5rnrra@jpeg)
November 26, 2025 at 10:32 PM
Reposted by Sara McArdle
Python notebook from a two year old paper:
Oh, no, I cannot run, there is a slight mismatch of a logging library.
ImageJ plugin from 2001 running on Quantum Java 51 in 2078:
Your 100 petabyte temporal hologram was successfully thresholded.
Oh, no, I cannot run, there is a slight mismatch of a logging library.
ImageJ plugin from 2001 running on Quantum Java 51 in 2078:
Your 100 petabyte temporal hologram was successfully thresholded.
November 20, 2025 at 5:42 PM
Python notebook from a two year old paper:
Oh, no, I cannot run, there is a slight mismatch of a logging library.
ImageJ plugin from 2001 running on Quantum Java 51 in 2078:
Your 100 petabyte temporal hologram was successfully thresholded.
Oh, no, I cannot run, there is a slight mismatch of a logging library.
ImageJ plugin from 2001 running on Quantum Java 51 in 2078:
Your 100 petabyte temporal hologram was successfully thresholded.
Reposted by Sara McArdle
Just 4 days until the start of I2K and its 33 totally free image analysis tutorials and events! Please share with your "home networks", especially early career researchers - the videos will be amazing and high-impact no matter how many people attend live, BUT (1/x)
November 13, 2025 at 2:32 PM
Just 4 days until the start of I2K and its 33 totally free image analysis tutorials and events! Please share with your "home networks", especially early career researchers - the videos will be amazing and high-impact no matter how many people attend live, BUT (1/x)
Reposted by Sara McArdle
California – this Election Day, vote yes on Prop 50.
California’s Prop 50 says that if Republicans are going to abuse the system to try and hang onto power, we’re going to counteract that abuse and create a level playing field in the midterm elections.
Make a plan to vote yes on Prop 50.
California’s Prop 50 says that if Republicans are going to abuse the system to try and hang onto power, we’re going to counteract that abuse and create a level playing field in the midterm elections.
Make a plan to vote yes on Prop 50.
October 30, 2025 at 6:49 PM
California – this Election Day, vote yes on Prop 50.
California’s Prop 50 says that if Republicans are going to abuse the system to try and hang onto power, we’re going to counteract that abuse and create a level playing field in the midterm elections.
Make a plan to vote yes on Prop 50.
California’s Prop 50 says that if Republicans are going to abuse the system to try and hang onto power, we’re going to counteract that abuse and create a level playing field in the midterm elections.
Make a plan to vote yes on Prop 50.
Took my daughter to one of the San Diego No Kings rallies, because even she knows that you have to stand up and say No to bullies.
October 19, 2025 at 4:53 AM
Took my daughter to one of the San Diego No Kings rallies, because even she knows that you have to stand up and say No to bullies.
Reposted by Sara McArdle
Wouldn’t it be cool if this photo of Obama receiving his Noble Peace Prize went viral today? 🔄
October 10, 2025 at 7:11 PM
Wouldn’t it be cool if this photo of Obama receiving his Noble Peace Prize went viral today? 🔄
I'm thrilled to share that our work studying microglia morphological changes in early Alzheimer's in mice is up!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Unmasking Early Microglial Remodeling in an Alzheimer's Disease Mouse Model
Early neuroimmune remodeling is a critical yet understudied component of Alzheimer's disease (AD) pathogenesis. To investigate microglial contributions to AD development prior to overt plaque depositi...
www.biorxiv.org
October 8, 2025 at 5:18 PM
I'm thrilled to share that our work studying microglia morphological changes in early Alzheimer's in mice is up!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sara McArdle
We are thrilled to announce that our NEW Large Language Model will be released on 11.18.25.
October 1, 2025 at 2:38 PM
We are thrilled to announce that our NEW Large Language Model will be released on 11.18.25.
Reposted by Sara McArdle
Lip Sync Battle - Tom Holland
YouTube video by Comedy Central Latinoamérica
youtu.be
September 29, 2025 at 12:31 AM
Happy Fluorescence Friday!
Rainbow Z projection of lymph node follicular dendritic cells.
Rainbow Z projection of lymph node follicular dendritic cells.
September 5, 2025 at 10:44 PM
Happy Fluorescence Friday!
Rainbow Z projection of lymph node follicular dendritic cells.
Rainbow Z projection of lymph node follicular dendritic cells.
Reposted by Sara McArdle
Who say what now?!! BLUEY THE MOVIE?!! #bluey #myChildWillBeTooOldButIllStillGo
www.bluey.tv/blog/date-an...
www.bluey.tv/blog/date-an...
two cartoon animals hugging each other with the word seduff on the bottom right
ALT: two cartoon animals hugging each other with the word seduff on the bottom right
media.tenor.com
September 4, 2025 at 1:00 PM
Who say what now?!! BLUEY THE MOVIE?!! #bluey #myChildWillBeTooOldButIllStillGo
www.bluey.tv/blog/date-an...
www.bluey.tv/blog/date-an...
I got this in my head and I couldn't focus on work until it existed.
Microscopy image file alignment chart, based on how I feel if you give me an image to analyze:
Microscopy image file alignment chart, based on how I feel if you give me an image to analyze:
August 7, 2025 at 9:27 PM
I got this in my head and I couldn't focus on work until it existed.
Microscopy image file alignment chart, based on how I feel if you give me an image to analyze:
Microscopy image file alignment chart, based on how I feel if you give me an image to analyze:
Reposted by Sara McArdle
Ready to automate your #microscopy #imageanalysis tasks? Applications are now open for our next "Introduction to Image Analysis" training course, in London at the @crick.ac.uk on October 27th-28th, 2025! 🔬💻
More info ⬇️
www.crick.ac.uk/whats-on/int...
More info ⬇️
www.crick.ac.uk/whats-on/int...
Introduction to image analysis
www.crick.ac.uk
August 6, 2025 at 6:38 PM
Ready to automate your #microscopy #imageanalysis tasks? Applications are now open for our next "Introduction to Image Analysis" training course, in London at the @crick.ac.uk on October 27th-28th, 2025! 🔬💻
More info ⬇️
www.crick.ac.uk/whats-on/int...
More info ⬇️
www.crick.ac.uk/whats-on/int...
Reposted by Sara McArdle
It's not just #NIH. It's not just #NSF. It's not just #NASA.
The whole scientific community has to make clear that all science across fed agencies is being destroyed in the US.
We can't just ask for our particular piece of the pie. The whole pie is being thrown out - saving your bit won't work.
The whole scientific community has to make clear that all science across fed agencies is being destroyed in the US.
We can't just ask for our particular piece of the pie. The whole pie is being thrown out - saving your bit won't work.
June 25, 2025 at 2:11 PM
Reposted by Sara McArdle
Every flashbang could instead be a meal for a poor kid. Every hotel room for a National Guardsman deployed to fire at our neighbors could house a homeless vet. Every "less-than-lethal" bullet pulled from a journalist's eye could be already needed healthcare for anyone else. All of this is a choice.
June 11, 2025 at 4:22 PM
Every flashbang could instead be a meal for a poor kid. Every hotel room for a National Guardsman deployed to fire at our neighbors could house a homeless vet. Every "less-than-lethal" bullet pulled from a journalist's eye could be already needed healthcare for anyone else. All of this is a choice.
Reposted by Sara McArdle
It's not that we might lose our jobs. It's that all of it will disappear or mutate beyond recognition. I worry we're not talking or thinking enough about this deeper sadness hiding behind our immediate anxieties and it's this heaviness that has us all at a breaking point.
May 15, 2025 at 2:35 AM
It's not that we might lose our jobs. It's that all of it will disappear or mutate beyond recognition. I worry we're not talking or thinking enough about this deeper sadness hiding behind our immediate anxieties and it's this heaviness that has us all at a breaking point.
Reposted by Sara McArdle
Cleansing the timeline with video from the Cincinnati Zoo & Botanical Garden.
May 7, 2025 at 7:11 PM
Cleansing the timeline with video from the Cincinnati Zoo & Botanical Garden.
Reposted by Sara McArdle
🚀 Tired of manual image analysis or scared of scripting?
Our self-paced “ImageJ Macro Scripting for Automatic Image Analysis” course makes automation easy—no coding experience needed!
Start from scratch & build pro-level macros.
www.biovoxxel.de/individual-w...
#ImageJ #MacroScripting
Our self-paced “ImageJ Macro Scripting for Automatic Image Analysis” course makes automation easy—no coding experience needed!
Start from scratch & build pro-level macros.
www.biovoxxel.de/individual-w...
#ImageJ #MacroScripting
April 23, 2025 at 2:59 PM
🚀 Tired of manual image analysis or scared of scripting?
Our self-paced “ImageJ Macro Scripting for Automatic Image Analysis” course makes automation easy—no coding experience needed!
Start from scratch & build pro-level macros.
www.biovoxxel.de/individual-w...
#ImageJ #MacroScripting
Our self-paced “ImageJ Macro Scripting for Automatic Image Analysis” course makes automation easy—no coding experience needed!
Start from scratch & build pro-level macros.
www.biovoxxel.de/individual-w...
#ImageJ #MacroScripting
Reposted by Sara McArdle
Bioimaging and bioimage analysis friends, some help if you have 2-3 mins; for a paper, we're trying to estimate the number of biologists trained in open source software or tools in the last ~5 years. (1/2) #bioimaging #microscopy #bioimageanalysis
April 8, 2025 at 2:32 PM
Bioimaging and bioimage analysis friends, some help if you have 2-3 mins; for a paper, we're trying to estimate the number of biologists trained in open source software or tools in the last ~5 years. (1/2) #bioimaging #microscopy #bioimageanalysis
Reposted by Sara McArdle
WATCH: Elephants at the San Diego Zoo Safari Park react to Monday's 5.2 magnitude earthquake that shook San Diego County. The elephants formed an "alert circle" meant to protect the young and the entire herd from any threats, according to the San Diego Zoo Wildlife Alliance.
April 14, 2025 at 10:46 PM
WATCH: Elephants at the San Diego Zoo Safari Park react to Monday's 5.2 magnitude earthquake that shook San Diego County. The elephants formed an "alert circle" meant to protect the young and the entire herd from any threats, according to the San Diego Zoo Wildlife Alliance.
Reposted by Sara McArdle
Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.
April 10, 2025 at 1:38 PM
Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.
Reposted by Sara McArdle
If you train people in ImageJ, Fiji, whatever, even if it isn't your day job, please let us know, and please share this post! Thanks a ton, we really appreciate it. (2/2) forms.gle/C8dUpg8qZkbD... #bioimaging #microscopy #bioimageanalysis
Open Source Bioimage Analysis Training Survey
We are attempting for a publication to estimate the number of biologists who have attended a tutorial or training course in open source bioimage analysis (especially user friendly tools, but anything ...
forms.gle
April 8, 2025 at 2:32 PM
If you train people in ImageJ, Fiji, whatever, even if it isn't your day job, please let us know, and please share this post! Thanks a ton, we really appreciate it. (2/2) forms.gle/C8dUpg8qZkbD... #bioimaging #microscopy #bioimageanalysis
Reposted by Sara McArdle
Reposted by Sara McArdle
We can upload 3 minute videos now.
YOU KNOW THE RULE
YOU KNOW THE RULE
March 10, 2025 at 7:52 PM
We can upload 3 minute videos now.
YOU KNOW THE RULE
YOU KNOW THE RULE
Everyone knows about the time Sen Cory Booker literally rescued a woman from a burning building, right? And helped a freezing dog and shoveled snow for disabled constituents? There's a reason we called him Super Mayor!
April 2, 2025 at 6:30 PM
Everyone knows about the time Sen Cory Booker literally rescued a woman from a burning building, right? And helped a freezing dog and shoveled snow for disabled constituents? There's a reason we called him Super Mayor!