Sasha (Aleksandra) Petrovskaya
@sashapetrovskaia.bsky.social
PhD student at Copenhagen University//
Martin Lauritzen Lab//
Main interest in neurodegeneration/ brain vascularisation/ drug delivery/ molecular aspects of memory formation/ microscopy
Martin Lauritzen Lab//
Main interest in neurodegeneration/ brain vascularisation/ drug delivery/ molecular aspects of memory formation/ microscopy
Pinned
An AD mouse brain with therapeutic antibody (in blue) and smooth muscle cells (in yellow).The first attempt, but quite successful. Thanks to @dvonwangenheim.bsky.social
#LISH25
#LISH25
Reposted by Sasha (Aleksandra) Petrovskaya
New on bioRxiv! 🚨
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8
November 20, 2025 at 9:04 PM
New on bioRxiv! 🚨
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8
Reposted by Sasha (Aleksandra) Petrovskaya
Huge thanks to @paveltomancak.bsky.social and @embo.org for hosting this year's amazing Light Sheet Microscopy course #LISH25. Our @dvonwangenheim.bsky.social and team were thrilled to capture beautiful images of many samples with AxL Cleared Tissue LightSheet 🔬
🌍 www.intelligent-imaging.com/AxL
🌍 www.intelligent-imaging.com/AxL
August 22, 2025 at 5:41 PM
Huge thanks to @paveltomancak.bsky.social and @embo.org for hosting this year's amazing Light Sheet Microscopy course #LISH25. Our @dvonwangenheim.bsky.social and team were thrilled to capture beautiful images of many samples with AxL Cleared Tissue LightSheet 🔬
🌍 www.intelligent-imaging.com/AxL
🌍 www.intelligent-imaging.com/AxL
Thank you @paveltomancak.bsky.social @olafselchow.bsky.social @dvonwangenheim.bsky.social @bundschuhst.bsky.social @ereynaud.bsky.social @cuencam15.bsky.social Vlado, Stephan for a life-changing lightsheet experience towards even more beautiful and high-quality science
#LISH25 final student team presentations. #SPIMply_the_Best
August 22, 2025 at 4:44 PM
Thank you @paveltomancak.bsky.social @olafselchow.bsky.social @dvonwangenheim.bsky.social @bundschuhst.bsky.social @ereynaud.bsky.social @cuencam15.bsky.social Vlado, Stephan for a life-changing lightsheet experience towards even more beautiful and high-quality science
It was such a lovely (though a bit tough) experience for me! Thanks to the organiser @paveltomancak.bsky.social for the inspiration for this long trip (even if it was the “minimal version”) and for another great day at #LISH25.
#LISH25 free day ride. Epic. Almost 90 km.
August 17, 2025 at 7:38 AM
It was such a lovely (though a bit tough) experience for me! Thanks to the organiser @paveltomancak.bsky.social for the inspiration for this long trip (even if it was the “minimal version”) and for another great day at #LISH25.
Reposted by Sasha (Aleksandra) Petrovskaya
Love these names 😆
August 15, 2025 at 9:42 AM
Love these names 😆
An AD mouse brain with therapeutic antibody (in blue) and smooth muscle cells (in yellow).The first attempt, but quite successful. Thanks to @dvonwangenheim.bsky.social
#LISH25
#LISH25
August 14, 2025 at 7:12 PM
An AD mouse brain with therapeutic antibody (in blue) and smooth muscle cells (in yellow).The first attempt, but quite successful. Thanks to @dvonwangenheim.bsky.social
#LISH25
#LISH25
The world behind LS7 and Blaze starts with 3i for me. Very excited to see the result of an overnight imaging #LISH5 #AD #neuroscience
August 13, 2025 at 7:53 PM
The world behind LS7 and Blaze starts with 3i for me. Very excited to see the result of an overnight imaging #LISH5 #AD #neuroscience
Reposted by Sasha (Aleksandra) Petrovskaya
My tutorial materials & slides about #Reproducible #BioImageAnalysis using Python, Napari, Jupyter and #AI are available #openaccess.
Thanks to #EMBOlsm25 for having me! It so great to visit friends at my former academic home campus for a couple of days 🤩
scads.github.io/embo-lsm-bia...
Thanks to #EMBOlsm25 for having me! It so great to visit friends at my former academic home campus for a couple of days 🤩
scads.github.io/embo-lsm-bia...
August 12, 2025 at 5:57 PM
My tutorial materials & slides about #Reproducible #BioImageAnalysis using Python, Napari, Jupyter and #AI are available #openaccess.
Thanks to #EMBOlsm25 for having me! It so great to visit friends at my former academic home campus for a couple of days 🤩
scads.github.io/embo-lsm-bia...
Thanks to #EMBOlsm25 for having me! It so great to visit friends at my former academic home campus for a couple of days 🤩
scads.github.io/embo-lsm-bia...
Reposted by Sasha (Aleksandra) Petrovskaya
We teach also #Napari at #LISH25. By @haesleinhuepf.bsky.social highlighting the awesome power of #Jupyter_notebooks for #reproducibility
August 12, 2025 at 2:57 PM
We teach also #Napari at #LISH25. By @haesleinhuepf.bsky.social highlighting the awesome power of #Jupyter_notebooks for #reproducibility
It has been an amazing day#1 of the Light Sheet Microscopy Course #LISH25 in Dresden; excited to look at the microscopy world beyond Blaze and Light sheet 7
August 11, 2025 at 8:53 PM
It has been an amazing day#1 of the Light Sheet Microscopy Course #LISH25 in Dresden; excited to look at the microscopy world beyond Blaze and Light sheet 7
Reposted by Sasha (Aleksandra) Petrovskaya
Excited to present our study in @natneuro.nature.com: a deep brain pathway that triggers safety-driven movement—overriding needs like finding food or social contacts. A look into how the brain weighs deep instincts. Congrats to all and first author @nkrauth.bsky.social. shorturl.at/toYFN
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs - Nature Neuroscience
Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...
shorturl.at
May 28, 2025 at 11:52 AM
Excited to present our study in @natneuro.nature.com: a deep brain pathway that triggers safety-driven movement—overriding needs like finding food or social contacts. A look into how the brain weighs deep instincts. Congrats to all and first author @nkrauth.bsky.social. shorturl.at/toYFN
Reposted by Sasha (Aleksandra) Petrovskaya
Your brain functions not only as a thinking organ but also as a miniature water factory. We here calculate how much water neuronal mitochondria produce by glucose oxidation: 300-400 ml. Of that amount, 100 ml go into brain's interstitial fluid. fluidsbarrierscns.biomedcentral.com/articles/10....
A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep - Fluids and Barriers of the CNS
Maintaining brain fluid homeostasis is of critical importance for creating a stable environment conducive to optimal neuronal functioning, nutrient distribution, and waste product removal. In this stu...
fluidsbarrierscns.biomedcentral.com
May 6, 2025 at 6:21 PM
Your brain functions not only as a thinking organ but also as a miniature water factory. We here calculate how much water neuronal mitochondria produce by glucose oxidation: 300-400 ml. Of that amount, 100 ml go into brain's interstitial fluid. fluidsbarrierscns.biomedcentral.com/articles/10....