Samuel Le Meur-Diebolt
@sdiebolt.bsky.social
Research Fellow in CortexLab @UCL 🧑🔬 • Functional ultrasound imaging & data science 🔊🧠 • samuel.diebolt.io
Pinned
www.biorxiv.org
🚨 New preprint alert!
We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠
Our results show how they reduce motion artifacts and impact seed-based connectivity analyses.
Check it out on @biorxivpreprint.bsky.social 👇
🔗 www.biorxiv.org/content/10.1...
We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠
Our results show how they reduce motion artifacts and impact seed-based connectivity analyses.
Check it out on @biorxivpreprint.bsky.social 👇
🔗 www.biorxiv.org/content/10.1...
Long-awaited #fUSI - #BIDS meeting scheduled! 🧠
📅 Nov 27, 5PM Paris time
🎯 Finalizing BEP for BIDS maintainer discussions
Implemented fUSI-BIDS or planning to? We need your input to strengthen the spec. Join us!
Details on the specification GDoc (docs.google.com/document/d/1...)
📅 Nov 27, 5PM Paris time
🎯 Finalizing BEP for BIDS maintainer discussions
Implemented fUSI-BIDS or planning to? We need your input to strengthen the spec. Join us!
Details on the specification GDoc (docs.google.com/document/d/1...)
fUSI-BIDS extension proposal v0.0.11
BIDS Extension Proposal 40 (BEP040): fUSI-BIDS version 0.0.11 Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <[email protected]...
docs.google.com
November 13, 2025 at 7:10 PM
Long-awaited #fUSI - #BIDS meeting scheduled! 🧠
📅 Nov 27, 5PM Paris time
🎯 Finalizing BEP for BIDS maintainer discussions
Implemented fUSI-BIDS or planning to? We need your input to strengthen the spec. Join us!
Details on the specification GDoc (docs.google.com/document/d/1...)
📅 Nov 27, 5PM Paris time
🎯 Finalizing BEP for BIDS maintainer discussions
Implemented fUSI-BIDS or planning to? We need your input to strengthen the spec. Join us!
Details on the specification GDoc (docs.google.com/document/d/1...)
Reposted by Samuel Le Meur-Diebolt
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
September 11, 2025 at 8:14 PM
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
Reposted by Samuel Le Meur-Diebolt
Nicolas Zucker, PhD student at @physmedparis.bsky.social was featured last Friday on "Les chantiers de la recherche" @radiofrance.fr, where he presented his work on functional ultrasound microscopy (fULM). 🎙️🧠
Podcast available here 👉 www.radiofrance.fr/francecultur...
Podcast available here 👉 www.radiofrance.fr/francecultur...
Parkinson, Alzheimer : l’imagerie médicale peut-elle nous aider à lutter contre les maladies cérébrales ?
Les progrès dans le domaine de l'imagerie médicale sont essentiels pour la médecine : en concevant des technologies de pointe pour mieux documenter le fonctionnement du cerveau, les scientifiques ouvr...
www.radiofrance.fr
September 9, 2025 at 2:46 PM
Nicolas Zucker, PhD student at @physmedparis.bsky.social was featured last Friday on "Les chantiers de la recherche" @radiofrance.fr, where he presented his work on functional ultrasound microscopy (fULM). 🎙️🧠
Podcast available here 👉 www.radiofrance.fr/francecultur...
Podcast available here 👉 www.radiofrance.fr/francecultur...
Reposted by Samuel Le Meur-Diebolt
This looks pretty cool: ultrasound can now see through the skull! 🧠🔊
The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯)
Huge congrats to the authors!!!
www.biorxiv.org/content/10.1...
The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯)
Huge congrats to the authors!!!
www.biorxiv.org/content/10.1...
September 3, 2025 at 1:35 PM
This looks pretty cool: ultrasound can now see through the skull! 🧠🔊
The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯)
Huge congrats to the authors!!!
www.biorxiv.org/content/10.1...
The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯)
Huge congrats to the authors!!!
www.biorxiv.org/content/10.1...
Reposted by Samuel Le Meur-Diebolt
Today is the first day of the Neuroinformatics Unit Open Software Week, bringing together researchers from around the world for a week of training and collaborating on open source neuroscience software.
First day is a Python programming workshop.
neuroinformatics.dev/open-softwar...
#niu_osw
First day is a Python programming workshop.
neuroinformatics.dev/open-softwar...
#niu_osw
August 11, 2025 at 3:22 PM
Today is the first day of the Neuroinformatics Unit Open Software Week, bringing together researchers from around the world for a week of training and collaborating on open source neuroscience software.
First day is a Python programming workshop.
neuroinformatics.dev/open-softwar...
#niu_osw
First day is a Python programming workshop.
neuroinformatics.dev/open-softwar...
#niu_osw
ty is incredible for diagnostics AND as a language server! Orders of magnitude faster than Pyright and will eventually replace it. Still need Pyright for on-hover info for now, but we're moving toward a complete Astral-backed Python environment! ⚡
Today, we’re announcing the preview release of ty, an extremely fast type checker and language server for Python, written in Rust.
In early testing, it's 10x, 50x, even 100x faster than existing type checkers. (We've seen >600x speed-ups over Mypy in some real-world projects.)
In early testing, it's 10x, 50x, even 100x faster than existing type checkers. (We've seen >600x speed-ups over Mypy in some real-world projects.)
August 11, 2025 at 10:25 AM
ty is incredible for diagnostics AND as a language server! Orders of magnitude faster than Pyright and will eventually replace it. Still need Pyright for on-hover info for now, but we're moving toward a complete Astral-backed Python environment! ⚡
Reposted by Samuel Le Meur-Diebolt
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
A must read for anyone interested in studying spatial navigation with #fUSI! 🧠🗺️
@felipecybis.bsky.social really opened up new possibilities with this one!👇
@felipecybis.bsky.social really opened up new possibilities with this one!👇
🚨 Preprint alert 🚨
The main results of my PhD are online and I only now could find some time to post about it!
We explored the neurovascular activations of spatial navigation by using functional ultrasound imaging (fUSI) in freely moving rats during open field.
The main results of my PhD are online and I only now could find some time to post about it!
We explored the neurovascular activations of spatial navigation by using functional ultrasound imaging (fUSI) in freely moving rats during open field.
Speed Vascular Patterns in the Spatial Navigation System https://www.biorxiv.org/content/10.1101/2025.07.15.663536v1
August 3, 2025 at 12:00 PM
A must read for anyone interested in studying spatial navigation with #fUSI! 🧠🗺️
@felipecybis.bsky.social really opened up new possibilities with this one!👇
@felipecybis.bsky.social really opened up new possibilities with this one!👇
Reposted by Samuel Le Meur-Diebolt
Drumroll... The SPM team will announce that SPM is now fully accessible from Python! 🐍 Learn more about SPM-Python at the SPM roundtable event (Friday, 1pm) and poster number 1841 at #OHBM2025. Try the beta for yourself at github.com/spm/spm-python [2/7]
GitHub - spm/spm-python: The Python interface to SPM
The Python interface to SPM. Contribute to spm/spm-python development by creating an account on GitHub.
github.com
June 23, 2025 at 8:06 AM
Drumroll... The SPM team will announce that SPM is now fully accessible from Python! 🐍 Learn more about SPM-Python at the SPM roundtable event (Friday, 1pm) and poster number 1841 at #OHBM2025. Try the beta for yourself at github.com/spm/spm-python [2/7]
Reposted by Samuel Le Meur-Diebolt
New paper in Imaging Neuroscience by Théo Lambert, Alan Urban, et al:
Functional ultrasound imaging and neuronal activity: How accurate is the spatiotemporal match?
doi.org/10.1162/IMAG...
Functional ultrasound imaging and neuronal activity: How accurate is the spatiotemporal match?
doi.org/10.1162/IMAG...
June 21, 2025 at 5:41 PM
New paper in Imaging Neuroscience by Théo Lambert, Alan Urban, et al:
Functional ultrasound imaging and neuronal activity: How accurate is the spatiotemporal match?
doi.org/10.1162/IMAG...
Functional ultrasound imaging and neuronal activity: How accurate is the spatiotemporal match?
doi.org/10.1162/IMAG...
🧠✨ Amazing #fUSbrainDAYS2025 conference! Thanks to the organizers for bringing together the fUSI community.
Poll results (53 participants):
🏝️ Corsica vs Paris: 41 vs 11
🔬 fUSi vs fUS: 33 vs 14
Looks like we're heading to Corsica next year, and embracing #fUSI!
Poll results (53 participants):
🏝️ Corsica vs Paris: 41 vs 11
🔬 fUSi vs fUS: 33 vs 14
Looks like we're heading to Corsica next year, and embracing #fUSI!
June 21, 2025 at 10:05 AM
🧠✨ Amazing #fUSbrainDAYS2025 conference! Thanks to the organizers for bringing together the fUSI community.
Poll results (53 participants):
🏝️ Corsica vs Paris: 41 vs 11
🔬 fUSi vs fUS: 33 vs 14
Looks like we're heading to Corsica next year, and embracing #fUSI!
Poll results (53 participants):
🏝️ Corsica vs Paris: 41 vs 11
🔬 fUSi vs fUS: 33 vs 14
Looks like we're heading to Corsica next year, and embracing #fUSI!
Reposted by Samuel Le Meur-Diebolt
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
June 20, 2025 at 7:57 PM
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
🚨 New preprint alert!
We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠
Our results show how they reduce motion artifacts and impact seed-based connectivity analyses.
Check it out on @biorxivpreprint.bsky.social 👇
🔗 www.biorxiv.org/content/10.1...
We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠
Our results show how they reduce motion artifacts and impact seed-based connectivity analyses.
Check it out on @biorxivpreprint.bsky.social 👇
🔗 www.biorxiv.org/content/10.1...
www.biorxiv.org
June 18, 2025 at 2:35 PM
🚨 New preprint alert!
We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠
Our results show how they reduce motion artifacts and impact seed-based connectivity analyses.
Check it out on @biorxivpreprint.bsky.social 👇
🔗 www.biorxiv.org/content/10.1...
We benchmarked 792 denoising pipelines for #fUSI in awake mice 🐭🧠
Our results show how they reduce motion artifacts and impact seed-based connectivity analyses.
Check it out on @biorxivpreprint.bsky.social 👇
🔗 www.biorxiv.org/content/10.1...
Reposted by Samuel Le Meur-Diebolt
🧠 Excited to share our new paper just published in eBioMedicine
We report ~0.1 Hz hemodynamic waves after local neuroinflammation using functional ultrasound imaging — their presence and amplification partly driven by glial cells
📄 thelancet.com/journals/ebiom…#neuroinflammationo#fUSU#gliaia
We report ~0.1 Hz hemodynamic waves after local neuroinflammation using functional ultrasound imaging — their presence and amplification partly driven by glial cells
📄 thelancet.com/journals/ebiom…#neuroinflammationo#fUSU#gliaia
Lancet
https://thelancet.com/journals/ebiom…
June 13, 2025 at 6:17 PM
🧠 Excited to share our new paper just published in eBioMedicine
We report ~0.1 Hz hemodynamic waves after local neuroinflammation using functional ultrasound imaging — their presence and amplification partly driven by glial cells
📄 thelancet.com/journals/ebiom…#neuroinflammationo#fUSU#gliaia
We report ~0.1 Hz hemodynamic waves after local neuroinflammation using functional ultrasound imaging — their presence and amplification partly driven by glial cells
📄 thelancet.com/journals/ebiom…#neuroinflammationo#fUSU#gliaia
Reposted by Samuel Le Meur-Diebolt
An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Benchmarking methods for mapping functional connectivity in the brain - Nature Methods
In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...
www.nature.com
June 6, 2025 at 3:51 PM
An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Samuel Le Meur-Diebolt
So glad to see this released!
June 5, 2025 at 5:45 PM
So glad to see this released!
Reposted by Samuel Le Meur-Diebolt
🎓 My lab has 2 PhD positions with @cimecunitrento.bsky.social
1️⃣ 🧠 Watch the 🐭 brain in motion, with functional ultrasound imaging (fUSI)
2️⃣🧪 Mess with the 🐭 brain (experimentally) via causal perturbations + imaging
🔬 Neuro/physics/bioengeneering backgrounds welcome
👉Info ▶️https://lnkd.in/dDeTTDj2
1️⃣ 🧠 Watch the 🐭 brain in motion, with functional ultrasound imaging (fUSI)
2️⃣🧪 Mess with the 🐭 brain (experimentally) via causal perturbations + imaging
🔬 Neuro/physics/bioengeneering backgrounds welcome
👉Info ▶️https://lnkd.in/dDeTTDj2
May 6, 2025 at 3:29 PM
🎓 My lab has 2 PhD positions with @cimecunitrento.bsky.social
1️⃣ 🧠 Watch the 🐭 brain in motion, with functional ultrasound imaging (fUSI)
2️⃣🧪 Mess with the 🐭 brain (experimentally) via causal perturbations + imaging
🔬 Neuro/physics/bioengeneering backgrounds welcome
👉Info ▶️https://lnkd.in/dDeTTDj2
1️⃣ 🧠 Watch the 🐭 brain in motion, with functional ultrasound imaging (fUSI)
2️⃣🧪 Mess with the 🐭 brain (experimentally) via causal perturbations + imaging
🔬 Neuro/physics/bioengeneering backgrounds welcome
👉Info ▶️https://lnkd.in/dDeTTDj2
Reposted by Samuel Le Meur-Diebolt
🎨🧑🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊
anniegbryant.github.io/subcortex_vi...
anniegbryant.github.io/subcortex_vi...
May 4, 2025 at 10:13 AM
🎨🧑🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊
anniegbryant.github.io/subcortex_vi...
anniegbryant.github.io/subcortex_vi...
Reposted by Samuel Le Meur-Diebolt
Systems neuroscientists could use a tool that allows them to tweak neuronal activity and record at the same time. The Neuropixels Opto probe, although still a protoype, might be such a device.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.
www.thetransmitter.org
April 29, 2025 at 2:10 PM
Systems neuroscientists could use a tool that allows them to tweak neuronal activity and record at the same time. The Neuropixels Opto probe, although still a protoype, might be such a device.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
Reposted by Samuel Le Meur-Diebolt
"Choose France for Science!" *government cuts half a billion more to the research budget*
Le gouvernement annule 3,1 milliards d’euros de crédit pour les missions écologie, économie et recherche et enseignement supérieur
Selon un décret publié samedi au « Journal officiel », ces annulations sont faites dans le cadre de l’effort supplémentaire de 5 milliards d’euros pour 2025.
www.lemonde.fr
April 26, 2025 at 4:39 PM
"Choose France for Science!" *government cuts half a billion more to the research budget*
Reposted by Samuel Le Meur-Diebolt
New Call for International Researchers interested in working in France. From postdoc to senior PIs.
carrieres.cnrs.fr/actualites/i...
carrieres.cnrs.fr/actualites/i...
April 25, 2025 at 6:11 AM
New Call for International Researchers interested in working in France. From postdoc to senior PIs.
carrieres.cnrs.fr/actualites/i...
carrieres.cnrs.fr/actualites/i...
🚨 Next #fUSI-BIDS meeting 🚨
Hey fUSI users!
The next fUSI-BIDS meeting will take place tomorrow 23/04 at 5:00pm CEST. Please join us and participate in drafting this new standard! Details and meeting link are in the specification GDoc (docs.google.com/document/d/1...).
See you soon! 🧠
Hey fUSI users!
The next fUSI-BIDS meeting will take place tomorrow 23/04 at 5:00pm CEST. Please join us and participate in drafting this new standard! Details and meeting link are in the specification GDoc (docs.google.com/document/d/1...).
See you soon! 🧠
fUSI-BIDS extension proposal v0.0.11
BIDS Extension Proposal 40 (BEP040): fUSI-BIDS version 0.0.11 Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <[email protected]>...
docs.google.com
April 22, 2025 at 8:59 PM
🚨 Next #fUSI-BIDS meeting 🚨
Hey fUSI users!
The next fUSI-BIDS meeting will take place tomorrow 23/04 at 5:00pm CEST. Please join us and participate in drafting this new standard! Details and meeting link are in the specification GDoc (docs.google.com/document/d/1...).
See you soon! 🧠
Hey fUSI users!
The next fUSI-BIDS meeting will take place tomorrow 23/04 at 5:00pm CEST. Please join us and participate in drafting this new standard! Details and meeting link are in the specification GDoc (docs.google.com/document/d/1...).
See you soon! 🧠
Reposted by Samuel Le Meur-Diebolt
Neuroscientists should embrace variability in neuroimaging studies, according to researchers who showed that decision-making is associated with subtypes of brain activity.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/behavior/dur...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/behavior/dur...
During decision-making, brain shows multiple distinct subtypes of activity
Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.
www.thetransmitter.org
April 18, 2025 at 1:33 PM
Neuroscientists should embrace variability in neuroimaging studies, according to researchers who showed that decision-making is associated with subtypes of brain activity.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/behavior/dur...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/behavior/dur...
Reposted by Samuel Le Meur-Diebolt
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
www.nature.com
March 26, 2025 at 1:54 AM
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
Reposted by Samuel Le Meur-Diebolt
The impact of heterogeneous spatial autocorrelation on comparisons of brain maps | bioRxiv www.biorxiv.org/content/10.1...
March 24, 2025 at 1:08 AM
The impact of heterogeneous spatial autocorrelation on comparisons of brain maps | bioRxiv www.biorxiv.org/content/10.1...