Lightnews — Scholar-powered news

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Han Zhu @hanzhumd.bsky.social · Aug 18

It was great working with @seanmwu.bsky.social and @aliraissadati.bsky.social on this seminal work investigating the proof of concept use cell free mRNA biomarkers in ici myocarditis, a technology that can be expanded to other CV diseases! @stanfordmedicine.bsky.social @scvi-mavens.bsky.social

2 7

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Journal of Clinical Investigation @jci.org · Sep 2

Immune checkpoint inhibitors have transformed cancer therapy, but adverse events such as myocarditis remain hard to diagnose.

@aliraissadati.bsky.social @seanmwu.bsky.social & team offer a noninvasive, early-detection tool for ICI-induced myocarditis—plasma cf-mRNA profiling: buff.ly/fVioq2o

4 6

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Journal of Clinical Investigation @jci.org · Sep 6

ICYMI: Immune checkpoint inhibitors have transformed cancer therapy, but adverse events such as myocarditis remain hard to diagnose.

@aliraissadati.bsky.social @seanmwu.bsky.social & team offer a noninvasive, early-detection tool for ICI-induced myocarditis—plasma cf-mRNA profiling: buff.ly/d7GpTU0

2 5

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Alireza Raissadati @aliraissadati.bsky.social · Aug 15

Thrilled to share our work in @jclinical-invest.bsky.social demonstrating the potential of cell free mRNA as a liquid biopsy of myocardial inflammation! Many thanks to my fantastic coauthors and especially my mentor @seanmwu.bsky.social for their unwavering support!
www.jci.org/articles/vie...

JCI - Using plasma cell-free mRNA to profile immune response and myocardial damage in immune checkpoint inhibitor–induced myocarditis

Alireza Raissadati, Xuanyu Zhou, Harrison Chou, Yuhsin Vivian Huang, Shaheen Khatua, Yin Sun, Anne Xu, Sharon Loa, Arturo Hernandez, Han Zhu, Sean M. Wu

www.jci.org

1 5 8

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Arun Sharma @arunsharmaphd.bsky.social · Jul 25

Catching up with @seanmwu.bsky.social lab alumni including @hanzhumd.bsky.social and Soah Lee at #BCVS2025!

Reuniting with old friends is the best part of scientific meetings, other than the science of course! 🔬

2 7

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 27

No one I know has been drinking Coors for decades so I think we’re good.

1 1

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 24

Keynote speech @ #bcvs2025 by @benoitbruneau.bsky.social @UCSF discussing the regulation of gene expression during ❤️ development, now in 3D! With moderator Jennifer Davis & intro by Farah sheik @americanheart.bsky.social

2 2 37

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 24

Thinking of you and appreciating what you have done for the ❤️ development community.🙏

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 24

Great turnout for the event!
@hanzhumd.bsky.social @benoitbruneau.bsky.social

1 2

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 24

Continuing the tradition of StanfordCVI dinner reception at #bcvs2025 w great presentations from CVI alumni ArunSharma @ Cedar Sinai, Mingtao Zhao @ Cinncinati Childrens, & Instructors David Staudt & Masataka Nishiga (soon 2 be facuty @ OhioState @stanfordcvi.bsky.social @americanheart.bsky.social

1 1 4

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 23

Opening session of AHA #bcvs2025 w AHA Prez Stacey Rosen, FarahSheikh, Maria Kontariditis, followed by sarcomere structure biology w Stefan Raunser @ Max-Planck Institute Physiology, Michael Greenberg @ WUSTL & JC_Tardiff @ Univ of Az. @americanheart.bsky.social @benoitbruneau.bsky.social

3

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 23

Great turnout at AHA #BCVS2025 Early Career Session! The future of basic CV science is bright! Inspiring keynote lecture by David Kass at JohnsHopkins on his career in science. @stanfordmedicine.bsky.social @stanfordcvi.bsky.social @stanforddeptmed.bsky.social

6

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Jul 18

Congratulations!!!

Arianne Caudal, PhD @arianneinthelab.bsky.social · Jul 16

✨ Career update: Thrilled to share that I’ve received an NOA for the NIH K99/R00 Pathway to Independence Award. Thank you to my mentors for your endless support @Joseph_C_Wu @rongtian2.bsky.social @juliaritterhoff.bsky.social @chifungleephd.bsky.social @seanmwu.bsky.social @stanfordcvi.bsky.social

3

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Jeremy Berg @jeremymberg.bsky.social · Jul 6

A short Bluetorial about my early days as the Director of the National Institute of General Medical Sciences (NIGMS) at NIH.

The importance of feeling responsibility and taking pride in doing the best job you can

a cartoon says hey everybody an old man 's talking while bart simpson looks on

ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

media.tenor.com

5 72 260

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · May 29

We’ve been using DAX CoPilot @stanfordmedicine.bsky.social & the feedback has been very positive. Pt are always asked for permission before use. Saves a lot of time for clinicians & is far more accurate compare w notes without it. Ppl should reserve judgement before having any experience.

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · May 24

Warning-some of you might find it triggering to read the flagrant violation of 1st amendment rights by the government against Harvard. The lawsuit from Harvard today provides a detailed account of what has transpired in the past two months. www.nytimes.com/interactive/...

Read Harvard’s Lawsuit Against Trump (Gift Article)

Harvard University sued the Trump administration after it moved to block international students from enrolling.

www.nytimes.com

1 8

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Bailey Bowcutt @baileybowcutt.bsky.social · May 22

I'm a current Harvard graduate student and I found out today that I had my NSF GRFP terminated without notification. I was awarded this individual research fellowship before even choosing Harvard as my graduate school

45 310 900

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · May 18

Great to see you Jon in Dallas earlier this week! Look forward to catch up again in-person at the BCVS meeting in Baltimore later this July. 👍🙏

Jon Pagtakhan @jonpheart.bsky.social · May 15

Successful #AHA Council Operations Committee meeting yesterday, & continued deep strategic planning w/ the one & only BCVS Council Chair Elect @seanmwu.bsky.social Missed fearless leader BCVS Council Chair Dr. Maria Kontaridis!

👉 Join/renew AHA membership! bit.ly/AHAmember

1 6

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Helen Collins @drhelenecollin1.bsky.social · May 10

Sign up now if you are in Chicago or surrounding states. Registration $40 for trainees and $75 for faculty.
Great presentations.
Good networking opportunities.

Helen Collins @drhelenecollin1.bsky.social · Apr 18

🗣️🗣️calling all cardiovascular researchers in the Chicago area and surrounding states.This one day symposium at Loyola is a great opportunity for trainees and researchers to network, present their research, and hear from the great Dr. Leinwand. 🫀🫀🫀 #cardiosky @barefieldlab.bsky.social

1 5 7

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · May 6

Our so called Secretary of Education now writes official letters like Trump writes posts on X and Truth Social. This is the education level we’ll be having across the country once the administration guts all funding for science 2 universities & student support. 🤬🤬🤬

Eric Columbus @ericcolumbus.bsky.social · May 6

🚨🚨 Deranged letter from Education Secretary Linda McMahon to Harvard’s president, cutting off federal funding for any new grants.

Worth reading in full. It is NUTS.

THE SECRETARY OF EDUCATION
WASHINGTON, DC 20202
May 5, 2025
Dr. Alan Garber
Office of the President
Harvard University
Massachusetts Hall
Cambridge, MA 02138
Dr. Garber,
The Federal Government has a sacred responsibility to be a wise and important steward of American taxpayer dollars. Harvard University, despite amassing a largely tax-free $53.2 billion dollar endowment (larger than the GDP of 100 countries), receives billions of dollars of taxpayer largess each year. Receiving such taxpayer funds is a privilege, not a right. Yet instead of using these funds to advance the education of its students, Harvard is engaging in a systemic pattern of violating federal law. Where do many of these "students" come from, who are they, how do they get into Harvard, or even into our country—and why is there so much HATE? These are questions that must be answered, among many more, but the biggest question of all is, why will Harvard not give straightforward answers to the American public?
Harvard University has made a mockery of this country's higher education system. It has invited foreign students, who engage in violent behavior and show contempt for the United States of America, to its campus. In every way, Harvard has failed to abide by its legal obligations, its ethical and fiduciary duties, its transparency responsibilities, and any semblance of academic rigor. It had scrapped standardized testing requirements and a normalized grading system. This year Harvard was forced to adopt an embarrassing "remedial math" program for undergraduates.
Why is it, we ask, that Harvard has to teach simple and basic mathematics, when it is supposedly so hard to get into this "acclaimed university"? Who is getting in under such a low standard when others, with fabulous grades and a great understanding of the highest levels of mathematics, are being rejected?
Harvard has even been embroiled in humiliating plagiarism scandals, exposed clearly and plainly in the media, with respect to your then…

$running the institution in a totally chaotic way. Harvard alumnus and highly successful hedge fund manager Bill Ackman noted that, under her leadership, Harvard has become "a political advocacy organization for one party." Ackman has called for the resignation of Pritzker, concluding that the "[t)he mismanagement here is Penny Pritzker" and noting that any serious corporation would have removed her after a litany of recent failings and the fact that, incredibly, "Harvard is not in a good financial position." According to Ackman, one of the world's foremost finance experts, Harvard's so-called S53 billion endowment is "massively overstated as far as what it's really worth," and Harvard has irresponsibly taken out $8 billion in debt. If this is true, it is concerning evidence of Harvard's disastrous mismanagement, indicating an urgent need for massive reform-not continued taxpayer investment. If Harvard prefers not to change, then Harvard should have no problem using its overflowing endowment to fund its bloated bureaucracy. At its best, a university should fulfill the highest ideals of our Nation, and enlighten the thousands of hopeful students who walk through its magnificent gates. But Harvard has betrayed this ideal. Perhaps most alarmingly, Harvard has failed to abide by the United States Supreme Court's ruling demanding that it end its racial preferencing, and continues to engage in ugly racism in its undergraduate and graduate schools, and even within the Harvard Law Review itself. Our universities should be bastions of merit that reward and celebrate excellence and achievement. They should not be incubators of discrimination that encourage resentment and instill grievance and racism into our wonderful young Americans. The above concerns are only a fraction of the long list of Harvard's consistent violations of its own legal duties. Given these and other concerning allegations, this letter is to inform you that Harvard should no longer seek GRANTS from the fede…$

Federal Agencies. The Administration's priorities have not changed and today's letter marks the end of new grants for the University.
These requests will advance the best interests of Harvard University, so it can reclaim its status as a respected educational institution for the future leaders of America. Thank you for your attention to this matter!
Sincerely,
Linda E. McMahon
Secretary of Education

4

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · May 6

The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n

Yamuna Krishnan @krishnanyamuna.bsky.social · May 6

Harvard may have a lot of issues, but none of the accusations in this acid-tripping letter are it. Don't know whether to laugh or cry as I watch monkeys tear up pearl strings.

Eric Columbus @ericcolumbus.bsky.social · May 6

🚨🚨 Deranged letter from Education Secretary Linda McMahon to Harvard’s president, cutting off federal funding for any new grants.

Worth reading in full. It is NUTS.

7 84 280

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Apr 14

Great to see @harvard.edu take a stand on the unlawful infringement of the current government on academic freedom and freedom of speech. I’m proud to have trained as a fellow at Harvard Med/MGH & as an HMS Assist Prof previously. 👍👍👏👏💪💪
Now is the time for all other universities to do the same.

The Boston Globe @bostonglobe.com · Apr 14

Lawyers for Harvard University said the school will not comply with a new list of demands sent by the Trump administration on Friday.

Harvard says it will not yield to Trump’s demands - The Boston Globe

Lawyers for Harvard University said Monday the school will not comply with a list of expanded demands from the Trump administration.

www.bostonglobe.com

1 1 9

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Malinda Lo @malindalo.bsky.social · Apr 14

Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu

Harvard University

Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.

www.harvard.edu

110 1.5K 7K

Sean M. Wu, M.D. Ph.D. FACC FAHA @seanmwu.bsky.social · Apr 3

Nice!! They need to add one in Boston also.

Haobo Li, PhD @lihaobo.bsky.social · Apr 3

🤣 @seanmwu.bsky.social #Portland OR

2

Reposted by Sean M. Wu, M.D. Ph.D. FACC FAHA

Erin Michos, MD @erinmichos.bsky.social · Mar 29

#SOUL trial presented at #ACC25. Oral #semaglutide reduced 3-pt major adverse cardiovascular events by 14% in patients with T2D, even with high background SGLTi use. In exploratory analysis, oral sema also reduced major limb events. #CardioSky @accintouch.bsky.social

1 14 20