Stephanie Xie
@stephxie.bsky.social
2K followers 670 following 72 posts
Firstgen immigrant scientist, mom and partner in dual academic household. Studying metabolic and inflammatory heterogeneity in🩸hematopoietic stem cells and leukemia stem cells. @Princess Margaret Cancer Centre avid orchid lover. 🇺🇸 🇨🇦citizen.
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stephxie.bsky.social
Bye-Bye Bay of Fundy. See you next year.
View of Bay of Fundy from the bouldering rocks next to Sandy Cove beach Sunset over Bay of Fundy over looking Sandy Cove beach.
stephxie.bsky.social
The quiet beauty of a Sunday morning overlooking St Mary’s Bay. #nofiltersneeded #familyvacation
St Mary’s Bay in the village of Sandy Cove, NS Canada Wildflower on the shore of the bay.
Reposted by Stephanie Xie
gritsmanlab.bsky.social
Check out our new preprint on an epigenetic resistance mechanism to PI3 kinase inhibition in AML and a new combination therapy with an EZH1/2 inhibitor that depletes leukemic stem cells! Great effort by @thehematopoet and the whole team
thehematopoet.bsky.social
So excited to share a pre-print of my thesis work! Check it out to see how we can leverage an epigenetic resistance mechanism to PI3K inhibitors to target leukemic stem cells!! (Spoiler alert: PRC2 is involved!) Really proud of this work conducted with @gritsmanlab.bsky.social
biorxiv-cancer.bsky.social
Exploiting an Epigenetic Resistance Mechanism to PI3 Kinase Inhibition in Leukemic Stem Cells https://www.biorxiv.org/content/10.1101/2025.07.11.663968v1
Reposted by Stephanie Xie
ernstlaboratory.bsky.social
The Myeloid Workshop is back in ASH! Please contact the organizers if you have an exciting story that will not be out by December they are: Zuzana Tothova ,
@ernstlaboratory.bsky.social
@steidluli.bsky.social
@ericpietras.bsky.social
@kathrinbernt.bsky.social
@gritsmanlab.bsky.social
stephxie.bsky.social
Travel grants for trainees are available for the stellar FEBS Workshop on Aging in Hematopoiesis that will take place in Crete on October 20-24. Deadline for applications: July 31. More info: aginginhematopoiesis2025.febsevents.org/travel-grants
Febs workshop poster
stephxie.bsky.social
So proud of Team Stemmy! Interdisciplinary collabs are the way to make a difference for preventing and curing cancer. @pmresearch-uhn.bsky.social @uwaterloo.ca
uwcheritoncs.bsky.social
Three Waterloo grads — Isabella Di Biasio, Veronika Sustrova and Katarina Makivic — teamed up to automate blood stem cell analysis using ML and a custom scripting language. Their tool, developed with Princess Margaret Cancer Centre, aims to speed up cancer research.

cs.uwaterloo.ca/news/biochem...
In the photo from left to right: Veronika Sustrova, Katarina Makivic and Isabella Di Biasio
stephxie.bsky.social
Those in #Milan for #EHA2025, catch Angelica Varesi in her oral on this story live.

🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitution"
🗓 Thursday, June 12 | 🕔 17:00–17:15 CEST
📍 Brown Hall 1
stephxie.bsky.social
Preprint alert🚨‼️
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
ATP2B1 expression identifies human hematopoietic stem cells across… | Stephanie Xie
Those in #Milan for #EHA2025, catch Angelica Varesi in her oral on this story live. 🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitu...
www.linkedin.com
stephxie.bsky.social
Preprint alert🚨‼️
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
ATP2B1 expression identifies human hematopoietic stem cells across… | Stephanie Xie
Those in #Milan for #EHA2025, catch Angelica Varesi in her oral on this story live. 🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitu...
www.linkedin.com
stephxie.bsky.social
Thank you Vijay. So sorry to have missed you at AACR.
stephxie.bsky.social
This month has been a whirlwind. I am happy to announce I am the newest Scientist @pmresearch-uhn.bsky.social

The Xie lab 🧪will focus on understanding how inflammatory and metabolic stress promote aging and cancer risk in human🩸hematopoietic stem cells and preventative interventions.
Stephanie Xie lab logo
stephxie.bsky.social
This is the most deserving of honors. Congratulations to my long-time mentor Dr. John Dick!
uhn.ca
Congratulations to Dr. John Dick, Senior Scientist at UHN’s
@pmresearch-uhn.bsky.social, on his election to the National Academy of Sciences, one of the highest honours for a scientist.
Reposted by Stephanie Xie
stephxie.bsky.social
Thank you @bradwouters.com. You are too kind.
Reposted by Stephanie Xie
bradwouters.com
theaacr.bsky.social
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
stephxie.bsky.social
@aircanada.bsky.social Please get your act together. I will miss the plenary session of #AACR2025 and learn about groundbreaking cancer research because my flight got canceled 20 minutes before boarding. Unexpected mechanical failure. Last month too. That’s an awful trend.
Reposted by Stephanie Xie
theaacr.bsky.social
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
stephxie.bsky.social
I had so much fun. 🙏@eirinipapapetrou.bsky.social, Elvin Wagenblast, Chris Sturgeon, Franco Izzo for the hospitality @sinaiirm.bsky.social
A 2 for 1 visit with insightful feedback from the Leukemia Working Group.
eirinipapapetrou.bsky.social
Learned all about HSC-iMs and had a great time with @stephxie.bsky.social in NYC. Thank you for visiting us Steph! @kharaslab.bsky.social @gritsmanlab.bsky.social
stephxie.bsky.social
Still a New Yorker at heart. I love the skyline of my childhood city. Looking forward to talking 🩸🧪science with colleagues at Icahn Mount Sinai and MSKCC and seeing family.
Manhattan skyline from the plane at descent.
stephxie.bsky.social
Registration for the 2025 FEBS Workshop on the Molecular and Cellular Pathways of Aging in Hematopoiesis in Crete on October 20-24 is live! Check out the amazing lineup of invited speakers on normal and malignant 🩸🧪, CH, inflammation, niche and much more. lnkd.in/eamN_YHs
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
Reposted by Stephanie Xie
jeremymberg.bsky.social
Bluetorial: Women, courage, and leadership

What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com