Roy Walker
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synbioroy.bsky.social
Roy Walker
@synbioroy.bsky.social
Synthetic biologist
Research Fellow at Macquarie University
(and the ARC Centre of Excellence in Synthetic Biology)
Brewer

SBA Sydney Node Leader
Reposted by Roy Walker
Congratulations to our Centre Director Ian Paulsen on being awarded the prestigious Eureka Prize for Leadership in Science! 🎉

This award recognises his outstanding leadership in advancing synthetic biology in Australia and beyond. We couldn’t be prouder of this well-deserved achievement! 👏
🏆 Distinguished Professor Ian Paulsen @arccoesb.bsky.social is awarded the Eureka Prize for Leadership in Science. #EurekaPrizes

Learn more: youtu.be/NeQn8TR9GYk
September 4, 2025 at 12:24 AM
Reposted by Roy Walker
New @nature.com
The possibility that lithium deficiency is a driver of Alzheimer's disease. Experimental model shows Li depletion impedes amyloid clearance, and repletion in humans could be achieved with low doses
nature.com/articles/s41...
Lithium deficiency and the onset of Alzheimer’s disease - Nature
Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level.
nature.com
August 6, 2025 at 3:16 PM
Time flies! I’m currently looking for a new talented volunteer to lead the Sydney Node of SBA. If you’re interested in gaining some leadership experience, running a team, and organising some fun events, please let me know by the 22nd of August
August 6, 2025 at 12:16 AM
Reposted by Roy Walker
New paper out by @aliciamv.bsky.social 🤩🥳

…where we study the yeast-based antifungal compound and iron-chelator pulcherriminic acid

academic.oup.com/femsyr/advan...
Pulcherriminic acid Biosynthesis and Transport: Insights from a heterologous system in Saccharomyces cerevisiae
Abstract. Pulcherriminic acid is an iron chelator produced by some Kluyveromyces and Metschnikowia yeasts. Its biosynthesis is encoded by the four–gene PUL
academic.oup.com
July 29, 2025 at 11:27 AM
Reposted by Roy Walker
I’m petrified about today’s science news. Genetically modifying crabs to have cheetah genes? This could go sideways fast.
July 8, 2025 at 9:45 AM
Reposted by Roy Walker
It's 25 yrs to the day since the Human Genome Project & Craig Venter declared joint victory in sequencing the human genome - an ideal time for @wellcometrust.bsky.social to annouce their new project, involving our lab, to begin work towards synthesising human genomes. wellcome.org/news/researc...
Researchers take first steps to creating synthetic human genomes | Wellcome
Scientists are developing technology to create the first synthetic human chromosome. The ability to write large genomes could transform our understanding of health.
wellcome.org
June 26, 2025 at 12:29 PM
Reposted by Roy Walker
Well this couldn’t have come at a better time www.bbc.com/news/article...
Scientists at Loughborough University create 'world's smallest violin'
The violin is smaller than a human hair and has "laid the groundwork" for future research.
www.bbc.com
June 5, 2025 at 9:08 PM
Reposted by Roy Walker
What's going on in fungi?? Chromosomes are distributed across several different nuclei in Sclerotinia sclerotiorum and Botrytis cinerea

Article in @science.org here: www.science.org/doi/10.1126/...
And Perspective here: www.science.org/doi/10.1126/...
Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...
www.science.org
May 16, 2025 at 9:43 AM
Dear all – I’m re-sharing this open PhD scholarship. I’ve now managed to secure funding for international PhD entry (and MRes if required). Please email me with a EoI if interested. Thanks!

It's an old ad, but will soon be updated:

www.mq.edu.au/research/phd...
Uncovering novel methods to elucidate protein secretion in yeast
This inter-disciplinary project will apply advanced synthetic biology approaches and genomics to elucidate the genetic basis of protein secretion in yeast.
www.mq.edu.au
April 15, 2025 at 1:21 AM
Congrats, Daniel! All the best for the new role
I'm super excited and grateful-yesterday I was appointed full professor at the Centre for Molecular Biology (ZMBH) at the University of Heidelberg. I am very grateful to my team, colleagues and mentors who have helped me along the way. I very much look forward to the next phase.
April 1, 2025 at 8:39 AM
Reposted by Roy Walker
Just to prove to everyone that I am working during my sabbatical:
February 17, 2025 at 6:43 AM
I/We have a fully funded international PhD scholarship in sunny Sydney that’s just come online! This is part of an exciting collaboration between the ARC Centre of Excellence in Synthetic Biology and the Dementia Research Centre. More information here:

www.mq.edu.au/research/phd...
February 3, 2025 at 11:02 PM
Reposted by Roy Walker

Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome

Full text: www.nature.com/articles/s41...

#yeast #yeastbiology

From @hughiechops.bsky.social
January 24, 2025 at 11:00 AM
A great opportunity if you're in to automation!
Exciting opportunity! Max Planck Institute for Terrestrial Microbiology is looking for a Head of the DNA-Biofoundry MaxGENESYS. Join us in vibrant #Marburg - apply by 15 February 2025. #ScienceJobs #SyntheticBiology #Biofoundry @maxplanck.de
January 20, 2025 at 9:13 PM
Reposted by Roy Walker
I am looking for postdoc-level candidates interested in developing a joint application for the Australian National Intelligence Postdoctoral Grants to fund a position within a project on "Designing RNA with Custom Properties using AI". #synbio #ai

More info: www.jaschke-lab.science/opportunitie...
January 16, 2025 at 5:32 AM
A fantastic full professorship opportunity is now available at the University of Heidelberg - the focus is on various aspects of Synthetic Biology and Synthetic Genomics.

jobs.zeit.de/jobs/full-pr...
January 12, 2025 at 11:16 PM
Hi – I (we) have an open PhD position for an enthusiastic student in sunny Sydney! Explore new approaches to yeast protein secretion, microfluidics and flow cytometry. Feel free to reach out and apply here. Please note this is for domestic students only. www.mq.edu.au/research/phd...
November 22, 2024 at 12:39 AM
Just testing out BlueSky

Here's a link to our tRNA Neochromosome paper!
www.sciencedirect.com/science/arti...
December 14, 2023 at 8:36 AM