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SynOpen journal
@synopenjournal.bsky.social
An #OpenAccess Thieme journal. Fast, Fair & Flexible, and committed to providing an excellent publishing experience through the entire process.
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Driving innovation in synthetic chemistry? 🚀 SynOpen is a global platform for the latest research results in #ChemicalSciences. Here’s why that matters for your research:

👁️️ High Readership
📝 Graphical Reviews
👥 Rapid Select Crowd Review
...and more!

Submit today: bit.ly/SynOpenJournal
#OpenAccess
Potential new type of #herbicides! 🌱
In this paper, J. Frackenpohl & team report the design, #synthesis, and #biological evaluation of substituted azetidinyl carboxamides, developed through scaffold hopping and #bioisosteric strategies.

🔗 Read the full article: bit.ly/4iplJyn
#ChemSky #SAR
November 26, 2025 at 4:50 AM
Prof. Michael P. Doyle & L. De Angelis (UTSA) highlight how 1,2,3-triazine 1-oxides provide a powerful platform for constructing diverse #heterocycles. From nucleophilic substitution & #deoxygenation to Diels–Alder #reactions and more!

🔗 Read the graphical review: bit.ly/48qm7Jg
#ChemSky #Synthesis
November 21, 2025 at 10:32 AM
✨ New Graphical Review!
A. V. Dobrydnev presents overview of synthetic strategies for building endocyclic sulfoximines. They possess unique #physicochemical and structural features, including #chirality and thermal stability.

🔗 Read more: bit.ly/482WRr7
#ChemSky #OrganicChemistry #Heterocycles
November 19, 2025 at 9:02 AM
⚡ In this review, J. Yang & team highlight recent advances in metal-enabled #electrophotocatalysis, integrating photo-, electro-, and metal-catalyzed processes to develop #sustainable routes for C–H activation, #decarboxylation, and cross-coupling under mild conditions.

🔗 Read now: bit.ly/43vqgZH
November 13, 2025 at 9:09 AM
M. V. Kachaeva & team designed and synthesized novel oxazolo[4,5-d]pyrimidine derivatives showing strong activity against glioblastoma and lung #cancer cell lines.

🔍 #MachineLearning, #QSAR modeling, and #docking revealed carbonic anhydrase XII as a potential target.

👉 Read more: bit.ly/47NQt75
November 11, 2025 at 9:01 AM
Reposted by SynOpen journal
🚀 Countdown to SCNOW Virtual Summit, 6–7 Nov! 🌱♻️

Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact.

💻 Register NOW: cassyni.com/s/scnow-virt...

#SCNOWVirtualSummit #SCNOWPosterSession #Sustainability
October 28, 2025 at 11:21 AM
⚗️ A mild and #metal-free route to 2-hydroxy diarylureas!
This PIFA-mediated ring-opening/coupling of benzoxazoles gives valuable #urea scaffolds with high yields and broad substrate scope.

🔗 Read the full article by M. Yang & team: bit.ly/47rBv81
#ChemSky #OrganicChemistry
November 5, 2025 at 9:00 AM
🌱 From the Virtual Collection: #ClickChemistry and #DrugDiscovery
A simple, metal-free, and eco-friendly approach using chitosan·HCl enables rapid hydrazone #synthesis under mild conditions, delivering high yields and promising #antimycobacterial activity.

🔗 Read here: bit.ly/3WZ09Xl
#ChemSky
November 1, 2025 at 10:44 AM
🧩 From the Virtual Collection: #ClickChemistry and #DrugDiscovery
An efficient click-type formal [2+2] cycloaddition enables the formation of complex #chromophores with remarkable nonlinear optical (NLO) properties.

🔗 Read the full paper: bit.ly/4qpq87O
#ChemSky #OrganicChemistry #OpenAccess
October 23, 2025 at 9:09 AM
⚗️ From Virtual Collection: #ClickChemistry and #DrugDiscovery

N. Jahan & I. Ansary present a review on the synthesis of bioactive macrocycles using ring-closing metathesis, a powerful strategy enabling access to structures with promising #biological activities.

👉 Read here: bit.ly/4hjC3jv
#ChemSky
October 20, 2025 at 9:07 AM
​🚨 LAST CALL! The Thieme #Cheminar starts TODAY.
​Join the session, chaired by our EiC, Prof. Thierry Ollevier.

​Plus: Hear from the SynOpen Most Innovative Paper Award 2024 Winner, Prof. Benjamin Stokes!

⏰️ Starts 3:00 PM (CET).
🔗 Register now: bit.ly/48sqMLq
#ChemSky #Chemistry #Boron
October 16, 2025 at 9:23 AM
Join the next Thieme #Cheminar focusing on the role of boron in #OrganicSynthesis! ​Chaired by our SynOpen Editor-in-Chief, Prof. Thierry Ollevier.

​📅 Oct 16, 3 pm (CEST)

​Don't miss the opportunity to connect with leaders in the field!

​🔗 Secure your spot: bit.ly/48sqMLq
#ChemSky #Chemistry
October 13, 2025 at 8:24 AM
The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi "for the development of metal-organic frameworks."
Congratulations! 🎉

​Full details: www.nobelprize.org/prizes/chemi...
#ChemNobel #ChemSky #Nobel #Science
Nobel Prize in Chemistry 2025
The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks.”
www.nobelprize.org
October 8, 2025 at 10:21 AM
🧩 From the Virtual Collection: #ClickChemistry and #DrugDiscovery
Vinod K. Tiwari & team report a modular and efficient click approach for the synthesis of calix[4]arene-based glycodendrimers bearing lactose (G1) and galactose (G2) units.

👉 Read now: bit.ly/46Vjb5I
#ChemSky
October 7, 2025 at 9:36 AM
✨ From Graphical Reviews Virtual Collection
Liu & Szostak highlight breakthroughs in #amide N–C bond #activation, covering:
⚡ Acyl & decarbonylative coupling
⚡ Nucleophilic acyl addition
⚡ Key mechanistic insights

Read here: www.thieme-connect.com/products/ejo...
#ChemSky #Catalysis #Chemistry
October 1, 2025 at 9:38 AM
🏆 Big news from SynOpen!
The Most Innovative Paper #Award 2024 goes to Benjamin Stokes & team (Santa Clara University, USA) for their breakthrough in Pd-catalyzed transfer #hydrogenation. Congratulations! 🎉 👏

👉 Read more in the full press release + article:
www.thieme.de/en/thieme-ch...
September 27, 2025 at 12:07 PM
⚡ From Graphical Reviews Virtual Collection
#Electrochemistry offers sustainable C–Se bond formation! Explore selenylation, difunctionalization, #cyclization & cross-coupling in this graphical review by Hasimujiang & Ruan.

🔍 Read now:
www.thieme-connect.com/products/ejo...
#ChemSky
September 25, 2025 at 9:24 AM
#PeerReviewWeek2025 highlights the future of peer review in the AI era.

At SynOpen Journal, we recognize the potential of AI to assist reviewers and strengthen integrity, but also the need for transparency, safeguards, and a continued focus on human expertise.

#AI #PeerReview #OpenAccess #Thieme
🤖 Peer Review Week 2025: Rethinking Peer Review in the AI Era.🤖

Let’s discuss how #AI can boost efficiency & integrity while keeping human judgment central. Share your thoughts!

📌 Learn more: peerreviewweek.net/theme.php
Peer Review Guidelines: www.thieme.com/en-us/guidel...

#SCNOW
September 19, 2025 at 12:24 PM
✨ From Graphical Reviews Collection
#Chemical transformations of indole #alkaloids provide rapid access to novel scaffolds for #DrugDiscovery. Ring distortion strategies re-engineer natural products into diverse bioactive compounds.

🔍 Read now: www.thieme-connect.com/products/ejo...
#ChemSky
September 19, 2025 at 9:31 AM
✨ From Graphical Reviews Virtual Collection
Frustrated Lewis Pairs (FLPs) go beyond H₂ #activation, enabling hydroaminations, #oxidations, cycloisomerizations, and C–C/C–N bond formations.

🔍 Read the graphical #review by Zhou, Tavandashti & Paradies:
www.thieme-connect.com/products/ejo...
#ChemSky
September 16, 2025 at 9:29 AM
🔬 Donor–acceptor azulenes with absorption in the 380–600 nm range & intense blue photoluminescence open new paths for functional materials in organic optoelectronics.

📖 Explore the article by Merkhatuly et al.: www.thieme-connect.com/products/ejo...
#ChemSky #Science
September 12, 2025 at 9:30 AM
⚗️ Vicarious Nucleophilic Substitution (VNS) opens new doors in porphyrin #chemistry!
VNS reaction enables the synthesis of functionalized #porphyrin derivatives with wide synthetic potential.

📖 Explore the graphical review by Ostrowski & Mikus: www.thieme-connect.com/products/ejo...
September 9, 2025 at 8:25 AM
🧪 Explore the latest in #chlorination #science with the graphical review by Vogel, Pinto & Candeias. From green methods to novel reagents, discover sustainable strategies shaping #OrganicSynthesis!

🔗 Read here: www.thieme-connect.com/products/ejo...

#OpenAccess #Chemistry
August 29, 2025 at 8:18 AM
🔬 Explore the synthetic versatility of Woollins’ Reagent (W.R.)! From heterocycle formation to selenoic acid #synthesis, discover its wide-ranging applications! Check out the graphical review by da Silva, Chipoline & Ferreira for more.

🔗 Read here: www.thieme-connect.com/products/ejo...
August 22, 2025 at 8:23 AM