Nature Reviews Microbiology, Published online: 10 November 2025; doi:10.1038/s41579-025-01254-yMicrobial whole-genome sequencing is an important element of health-care-associated infection (HAI) prevention strategies. Focusing on specific high-priority antibiotic-resistant bacterial pathogens, this Review outlines the epidemiology and microbiology of HAIs and discusses the role of whole-genome sequencing in HAI prevention and surveillance.

This study elaborates on transmitted drug resistance (TDR) among antiretroviral therapy–naive people newly diagnosed with HIV in China. It was found that t

We use a mathematical model incorporating racial inequities in the United States to determine the effects of interventions aimed at ameliorating inequity i

This nationwide study of 2,027 Danish patients with MAC isolates (1991-2018) revealed declining mortality. Age, male sex, DMAC, and comorbidities were asso

Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptiv...

AbstractBackground. The duration of infectiousness following pulmonary tuberculosis treatment initiation remains uncertain. We aimed to assess whether a bu

Post-exposure doxycycline-based prophylaxis was associated with a significant increase in the frequency of N. gonorrhoeae isolates with high-level resistan

Ongoing high-risk behaviors continue to fuel HCV transmission among men who have sex with men (MSM), challenging elimination efforts. W

Impact of a multifaceted intervention including supportive care order sentence implementation on outpatient antibiotic prescribing for upper respiratory tract infections - Volume 5 Issue 1

Alberta is reporting its first measles death since outbreaks of the highly contagious illness began in March. The province says a baby, who was born prematurely after the mother became sick, died shor...

A review of 14 clinical trials involving more than 100,000 participants supports widespread RSV vaccination to reduce severe illness and hospitalisations.

A new report finds there are fewer antibacterial medicines in clinical pipelines than just two years ago and relatively few qualify as innovative.

Carbapenemase-producing Enterobacterales (CPE), traditionally thought to cause hospital-acquired infection in humans, are now emerging as agents of both community-acquired infections in humans as well as hospital-acquired infections in pets.