The Babak Lab
@thebabaklab.bsky.social
Research group of Prof. Maria (Masha) Babak at City University of Hong Kong
#anticancerdrugdiscovery #globalpublichealth #AI-assisteddrugdisovery
thebabaklab.com
#anticancerdrugdiscovery #globalpublichealth #AI-assisteddrugdisovery
thebabaklab.com
New hope for BRAF V600E mCRC patients: BREAKWATER shows EC+mFOLFOX6 nearly doubles survival vs. standard chemo.
A potential new first-line standard for this high-risk population.
Link in comments 👇
#mCRC #BRAF #ClinicalTrials #oncology
A potential new first-line standard for this high-risk population.
Link in comments 👇
#mCRC #BRAF #ClinicalTrials #oncology
June 30, 2025 at 12:37 PM
New hope for BRAF V600E mCRC patients: BREAKWATER shows EC+mFOLFOX6 nearly doubles survival vs. standard chemo.
A potential new first-line standard for this high-risk population.
Link in comments 👇
#mCRC #BRAF #ClinicalTrials #oncology
A potential new first-line standard for this high-risk population.
Link in comments 👇
#mCRC #BRAF #ClinicalTrials #oncology
🚀 Reminder: Our preprint “Overcoming Cisplatin Resistance via Deep Learning–Assisted Design of Platinum Complexes” is live on ChemRxiv!
We designed PlatinAI—a platinum complex active against cisplatin-resistant cells via a non-DNA-binding mechanism.
Link in comments 👇
#AI #Oncology #Metallodrugs
We designed PlatinAI—a platinum complex active against cisplatin-resistant cells via a non-DNA-binding mechanism.
Link in comments 👇
#AI #Oncology #Metallodrugs
June 27, 2025 at 3:19 PM
🚀 Reminder: Our preprint “Overcoming Cisplatin Resistance via Deep Learning–Assisted Design of Platinum Complexes” is live on ChemRxiv!
We designed PlatinAI—a platinum complex active against cisplatin-resistant cells via a non-DNA-binding mechanism.
Link in comments 👇
#AI #Oncology #Metallodrugs
We designed PlatinAI—a platinum complex active against cisplatin-resistant cells via a non-DNA-binding mechanism.
Link in comments 👇
#AI #Oncology #Metallodrugs
ChemBench: Testing AI vs. Human Chemists 🤖🧪🧑🔬
An open-source benchmark designed to evaluate how well large language models (LLMs) understand chemistry compared to human experts. Spoiler alert: human chemists still hold advantages in certain problem-solving areas.
Link in comments
#Chemistry #AI
An open-source benchmark designed to evaluate how well large language models (LLMs) understand chemistry compared to human experts. Spoiler alert: human chemists still hold advantages in certain problem-solving areas.
Link in comments
#Chemistry #AI
June 25, 2025 at 11:28 AM
ChemBench: Testing AI vs. Human Chemists 🤖🧪🧑🔬
An open-source benchmark designed to evaluate how well large language models (LLMs) understand chemistry compared to human experts. Spoiler alert: human chemists still hold advantages in certain problem-solving areas.
Link in comments
#Chemistry #AI
An open-source benchmark designed to evaluate how well large language models (LLMs) understand chemistry compared to human experts. Spoiler alert: human chemists still hold advantages in certain problem-solving areas.
Link in comments
#Chemistry #AI
🏥 New hope for better long-term outcomes in HNSCC!
KEYNOTE-689: Pembrolizumab before and after surgery improves progression-free survival & overall outcomes in HNSCC patients compared to standard treatment.
Link in comments
#oncology #immunotherapy #HNSCC #clinicaltrials
KEYNOTE-689: Pembrolizumab before and after surgery improves progression-free survival & overall outcomes in HNSCC patients compared to standard treatment.
Link in comments
#oncology #immunotherapy #HNSCC #clinicaltrials
June 23, 2025 at 9:48 AM
🏥 New hope for better long-term outcomes in HNSCC!
KEYNOTE-689: Pembrolizumab before and after surgery improves progression-free survival & overall outcomes in HNSCC patients compared to standard treatment.
Link in comments
#oncology #immunotherapy #HNSCC #clinicaltrials
KEYNOTE-689: Pembrolizumab before and after surgery improves progression-free survival & overall outcomes in HNSCC patients compared to standard treatment.
Link in comments
#oncology #immunotherapy #HNSCC #clinicaltrials
👩🔬 We trained a deep learning model to create a new platinum complex. It works.
Our latest research, “Overcoming Cisplatin Resistance via Deep Learning–Assisted De Novo Design of Platinum Complexes,” is now live on ChemRxiv! 🔬
Link in comments 👇
#AI #Oncology #Metallodrugs
Our latest research, “Overcoming Cisplatin Resistance via Deep Learning–Assisted De Novo Design of Platinum Complexes,” is now live on ChemRxiv! 🔬
Link in comments 👇
#AI #Oncology #Metallodrugs
June 21, 2025 at 1:49 PM
👩🔬 We trained a deep learning model to create a new platinum complex. It works.
Our latest research, “Overcoming Cisplatin Resistance via Deep Learning–Assisted De Novo Design of Platinum Complexes,” is now live on ChemRxiv! 🔬
Link in comments 👇
#AI #Oncology #Metallodrugs
Our latest research, “Overcoming Cisplatin Resistance via Deep Learning–Assisted De Novo Design of Platinum Complexes,” is now live on ChemRxiv! 🔬
Link in comments 👇
#AI #Oncology #Metallodrugs
We gathered to say farewell to our amazing postdoctoral fellow, Raja, sending him off with spices, stories, and a whole lot of heart. 🌶️💬💛
Raja, we'll miss you and can’t wait to see where your path leads next! 🚀🌍
#Graduation #StudentLife #CareerJourney
Raja, we'll miss you and can’t wait to see where your path leads next! 🚀🌍
#Graduation #StudentLife #CareerJourney
June 20, 2025 at 9:30 AM
We gathered to say farewell to our amazing postdoctoral fellow, Raja, sending him off with spices, stories, and a whole lot of heart. 🌶️💬💛
Raja, we'll miss you and can’t wait to see where your path leads next! 🚀🌍
#Graduation #StudentLife #CareerJourney
Raja, we'll miss you and can’t wait to see where your path leads next! 🚀🌍
#Graduation #StudentLife #CareerJourney
Iron and the Gut Microbiome: A Delicate Balance with Clinical Implications
Iron is a key regulator of host–microbiome ecology and immune-metabolic balance.
Exciting work in Nature Microbiology.
Full article link in comments 👇
#Microbiome #IronMetabolism #Immunology
Iron is a key regulator of host–microbiome ecology and immune-metabolic balance.
Exciting work in Nature Microbiology.
Full article link in comments 👇
#Microbiome #IronMetabolism #Immunology
June 18, 2025 at 11:18 AM
Iron and the Gut Microbiome: A Delicate Balance with Clinical Implications
Iron is a key regulator of host–microbiome ecology and immune-metabolic balance.
Exciting work in Nature Microbiology.
Full article link in comments 👇
#Microbiome #IronMetabolism #Immunology
Iron is a key regulator of host–microbiome ecology and immune-metabolic balance.
Exciting work in Nature Microbiology.
Full article link in comments 👇
#Microbiome #IronMetabolism #Immunology
🧪New data support monoclonal antibodies as next-gen malaria prevention.
CIS43LS is the first mAb to show high efficacy in a real-world malaria-endemic setting proven in a Phase 2 trial in Mali.
Link in comments
#ClinicalTrials #InfectiousDiseases #MonoclonalAntibodies
CIS43LS is the first mAb to show high efficacy in a real-world malaria-endemic setting proven in a Phase 2 trial in Mali.
Link in comments
#ClinicalTrials #InfectiousDiseases #MonoclonalAntibodies
June 16, 2025 at 8:27 AM
🧪New data support monoclonal antibodies as next-gen malaria prevention.
CIS43LS is the first mAb to show high efficacy in a real-world malaria-endemic setting proven in a Phase 2 trial in Mali.
Link in comments
#ClinicalTrials #InfectiousDiseases #MonoclonalAntibodies
CIS43LS is the first mAb to show high efficacy in a real-world malaria-endemic setting proven in a Phase 2 trial in Mali.
Link in comments
#ClinicalTrials #InfectiousDiseases #MonoclonalAntibodies
Honored to share that our lab member, Dr. Jemma Arakelyan (CEO, Institute of Cancer and Crisis), spoke at #ASCO2025 in Chicago—addressing the impact of conflict on cancer care and the urgent need for innovation in crisis-affected regions.
#ASCO2025 #CancerCare #GlobalHealth
#ASCO2025 #CancerCare #GlobalHealth
June 13, 2025 at 6:05 AM
Honored to share that our lab member, Dr. Jemma Arakelyan (CEO, Institute of Cancer and Crisis), spoke at #ASCO2025 in Chicago—addressing the impact of conflict on cancer care and the urgent need for innovation in crisis-affected regions.
#ASCO2025 #CancerCare #GlobalHealth
#ASCO2025 #CancerCare #GlobalHealth
Smarter Cancer Decisions with AI GPT-4–based
🎯 Accuracy boost: 30.3% → 87.2% with multimodal tools (such as Vision Transformer, MedSAM, PubMed, OncoKB).
Is AI + domain-specific tools the future of precision oncology?
Link in comments
#Oncology #AI #GPT4 #HealthTech
🎯 Accuracy boost: 30.3% → 87.2% with multimodal tools (such as Vision Transformer, MedSAM, PubMed, OncoKB).
Is AI + domain-specific tools the future of precision oncology?
Link in comments
#Oncology #AI #GPT4 #HealthTech
June 11, 2025 at 10:30 AM
Smarter Cancer Decisions with AI GPT-4–based
🎯 Accuracy boost: 30.3% → 87.2% with multimodal tools (such as Vision Transformer, MedSAM, PubMed, OncoKB).
Is AI + domain-specific tools the future of precision oncology?
Link in comments
#Oncology #AI #GPT4 #HealthTech
🎯 Accuracy boost: 30.3% → 87.2% with multimodal tools (such as Vision Transformer, MedSAM, PubMed, OncoKB).
Is AI + domain-specific tools the future of precision oncology?
Link in comments
#Oncology #AI #GPT4 #HealthTech
Tarlatamab shows superior outcomes in relapsed SCLC
In the phase 3 DeLLphi-304 trial, Tarlatamab significantly improved overall survival and reduced severe AE compared to chemotherapy in relapsed SCLC after platinum-based treatment.
Link in comments
#ClinicalTrials #SCLC # Oncology
In the phase 3 DeLLphi-304 trial, Tarlatamab significantly improved overall survival and reduced severe AE compared to chemotherapy in relapsed SCLC after platinum-based treatment.
Link in comments
#ClinicalTrials #SCLC # Oncology
June 9, 2025 at 10:04 AM
Tarlatamab shows superior outcomes in relapsed SCLC
In the phase 3 DeLLphi-304 trial, Tarlatamab significantly improved overall survival and reduced severe AE compared to chemotherapy in relapsed SCLC after platinum-based treatment.
Link in comments
#ClinicalTrials #SCLC # Oncology
In the phase 3 DeLLphi-304 trial, Tarlatamab significantly improved overall survival and reduced severe AE compared to chemotherapy in relapsed SCLC after platinum-based treatment.
Link in comments
#ClinicalTrials #SCLC # Oncology
Amid busy, fulfilling days, we paused to say farewell to Chris Fung, Ho-jung Choe & Maryana Yarshova.
Hot pot, mahjong & shared laughter made it a night to remember.
We’re proud to have walked this path with you. Here's to the road ahead 🌟
#Graduation #StudentLife #CareerJourney
Hot pot, mahjong & shared laughter made it a night to remember.
We’re proud to have walked this path with you. Here's to the road ahead 🌟
#Graduation #StudentLife #CareerJourney
June 6, 2025 at 3:37 AM
Amid busy, fulfilling days, we paused to say farewell to Chris Fung, Ho-jung Choe & Maryana Yarshova.
Hot pot, mahjong & shared laughter made it a night to remember.
We’re proud to have walked this path with you. Here's to the road ahead 🌟
#Graduation #StudentLife #CareerJourney
Hot pot, mahjong & shared laughter made it a night to remember.
We’re proud to have walked this path with you. Here's to the road ahead 🌟
#Graduation #StudentLife #CareerJourney
🦠 Block nutrients, block infection: a new antimicrobial strategy emerges. Fascinating work in Science Advances!
Full article link in comments 👇
#Microbiology #LifeSciences #AntibioticResistance #ScientificResearch
Full article link in comments 👇
#Microbiology #LifeSciences #AntibioticResistance #ScientificResearch
June 4, 2025 at 6:35 AM
🦠 Block nutrients, block infection: a new antimicrobial strategy emerges. Fascinating work in Science Advances!
Full article link in comments 👇
#Microbiology #LifeSciences #AntibioticResistance #ScientificResearch
Full article link in comments 👇
#Microbiology #LifeSciences #AntibioticResistance #ScientificResearch
🎉 Congrats to Pikting Izzy Cheung from University at Albany, SUNY — winner of Falling Walls Lab Hong Kong!
She’ll head to Berlin to join the global finale of this pitch competition for emerging innovators with bold, world-changing ideas.
#FallingWallsLab #Innovation
She’ll head to Berlin to join the global finale of this pitch competition for emerging innovators with bold, world-changing ideas.
#FallingWallsLab #Innovation
June 2, 2025 at 2:23 PM
🎉 Congrats to Pikting Izzy Cheung from University at Albany, SUNY — winner of Falling Walls Lab Hong Kong!
She’ll head to Berlin to join the global finale of this pitch competition for emerging innovators with bold, world-changing ideas.
#FallingWallsLab #Innovation
She’ll head to Berlin to join the global finale of this pitch competition for emerging innovators with bold, world-changing ideas.
#FallingWallsLab #Innovation
Take a look at the latest interview the Babak Lab produced for the series #ConversationsThatShapeScience. This time, we had an insightful and inspiring chat with Prof. Denver Danfeng Li from City University of Hong Kong on his work on superconductors and beyond.
www.linkedin.com/posts/the-ba...
www.linkedin.com/posts/the-ba...
Interview with Prof. Denver Li | The Babak Lab
#ConversationsThatShapeScience: Insights from Danfeng L. 🔬
Don’t miss our fascinating interview with Prof. Denver Danfeng Li! During his interview, Prof. Li shared:
- How his work in materials scienc...
www.linkedin.com
June 1, 2025 at 1:19 PM
Take a look at the latest interview the Babak Lab produced for the series #ConversationsThatShapeScience. This time, we had an insightful and inspiring chat with Prof. Denver Danfeng Li from City University of Hong Kong on his work on superconductors and beyond.
www.linkedin.com/posts/the-ba...
www.linkedin.com/posts/the-ba...
Exciting read of this week: AI Meets Chemistry!
New Nature paper introduces SIMGs—AI-enhanced molecular graphs that predict properties better than traditional methods by integrating quantum data. Scalable, interpretable, and free to try (simg.cheme.cmu.edu)!
doi.org/10.1038/s422...
New Nature paper introduces SIMGs—AI-enhanced molecular graphs that predict properties better than traditional methods by integrating quantum data. Scalable, interpretable, and free to try (simg.cheme.cmu.edu)!
doi.org/10.1038/s422...
June 1, 2025 at 1:14 PM
Exciting read of this week: AI Meets Chemistry!
New Nature paper introduces SIMGs—AI-enhanced molecular graphs that predict properties better than traditional methods by integrating quantum data. Scalable, interpretable, and free to try (simg.cheme.cmu.edu)!
doi.org/10.1038/s422...
New Nature paper introduces SIMGs—AI-enhanced molecular graphs that predict properties better than traditional methods by integrating quantum data. Scalable, interpretable, and free to try (simg.cheme.cmu.edu)!
doi.org/10.1038/s422...
Take a glimpse at the course developed by Prof. Maria Babak and her team, which had a significant impact for her winning the Teaching Excellence award this year 🥳🤩
(Video is longer than 1 min, so click the link below 🙏🏼)
www.linkedin.com/posts/the-ba...
#chemsky
(Video is longer than 1 min, so click the link below 🙏🏼)
www.linkedin.com/posts/the-ba...
#chemsky
#thebabaklablive #teachingexcellence #highereducation… | The Babak Lab
#TheBabakLabLive: Get a Glimpse of Prof. Babak's Course
This week, we continue the celebration of Prof. Maria (Masha) Babak, PhD's Teaching Excellence Award from College of Science.
At the ...
www.linkedin.com
May 16, 2025 at 1:28 PM
Take a glimpse at the course developed by Prof. Maria Babak and her team, which had a significant impact for her winning the Teaching Excellence award this year 🥳🤩
(Video is longer than 1 min, so click the link below 🙏🏼)
www.linkedin.com/posts/the-ba...
#chemsky
(Video is longer than 1 min, so click the link below 🙏🏼)
www.linkedin.com/posts/the-ba...
#chemsky
Huge congratulations to Prof. Maria Babak on winning the College of Science Teaching Excellence Award this year! 🎉 This recognition celebrates your outstanding contributions—thank you for inspiring excellence in education. We are proud to be your students! 👏
#CityUHK #Science #Education #chemsky
#CityUHK #Science #Education #chemsky
May 9, 2025 at 6:39 AM
Huge congratulations to Prof. Maria Babak on winning the College of Science Teaching Excellence Award this year! 🎉 This recognition celebrates your outstanding contributions—thank you for inspiring excellence in education. We are proud to be your students! 👏
#CityUHK #Science #Education #chemsky
#CityUHK #Science #Education #chemsky
Exciting article to read this week! Could it be the future of healing? 🤖
doi.org/10.1002/advs...
#chemsky
doi.org/10.1002/advs...
#chemsky
May 7, 2025 at 5:09 AM
Exciting article to read this week! Could it be the future of healing? 🤖
doi.org/10.1002/advs...
#chemsky
doi.org/10.1002/advs...
#chemsky
Prof. Babak had a chance to visit to 3 top universities in Uzbekistan. Mary thanks to Nargiza Amirova for the warm hospitality & brilliant organization! Excited for future collaborations! 🌍✨
May 5, 2025 at 10:56 AM
Prof. Babak had a chance to visit to 3 top universities in Uzbekistan. Mary thanks to Nargiza Amirova for the warm hospitality & brilliant organization! Excited for future collaborations! 🌍✨
Exciting read of this week at the Babak Lab! 10.1126/sciimmunol.adf4726
April 30, 2025 at 3:58 PM
Exciting read of this week at the Babak Lab! 10.1126/sciimmunol.adf4726
This week, Prof. Babak joined CityUHK's delegation to visit three top Kazakh Universities 🇰🇿 Staying true to her "work hard, play hard" approach, she discussed research projects and built connections with local students and academics. All while experiencing Kazakhstan's rich culture.
#chemsky
#chemsky
April 18, 2025 at 3:11 AM
This week, Prof. Babak joined CityUHK's delegation to visit three top Kazakh Universities 🇰🇿 Staying true to her "work hard, play hard" approach, she discussed research projects and built connections with local students and academics. All while experiencing Kazakhstan's rich culture.
#chemsky
#chemsky
New study in Nat. Genetics introduces MESA, a computational framework that quantitatively maps tissue organization by combining multiomics with ecological principles. The method reveals distinct cellular communities and identifies disease-associated patterns.
doi.org/10.1038/s41588-025-02119-z
doi.org/10.1038/s41588-025-02119-z
April 16, 2025 at 11:57 AM
New study in Nat. Genetics introduces MESA, a computational framework that quantitatively maps tissue organization by combining multiomics with ecological principles. The method reveals distinct cellular communities and identifies disease-associated patterns.
doi.org/10.1038/s41588-025-02119-z
doi.org/10.1038/s41588-025-02119-z
This week, Prof. Babak had the privilege of visiting Al-Farabi Kazakh National University in Almaty as part of City University of Hong Kong delegation. It was an inspiring opportunity to explore academic and research synergies between our institutions.
April 16, 2025 at 2:52 AM
This week, Prof. Babak had the privilege of visiting Al-Farabi Kazakh National University in Almaty as part of City University of Hong Kong delegation. It was an inspiring opportunity to explore academic and research synergies between our institutions.