@thedoctorisvin.bsky.social
Thanks @cancerdynamics.bsky.social for highlighting this interview with @columbiacancer.bsky.social for Blood Cancer Awareness Month and our work in @cohesinlab
This #BloodCancerAwarenessMonth, Dr. Aaron Viny (@thedoctorisvin.bsky.social) is shining a light on the lifesaving role of transplants in blood cancers & addressing some of the most persistent myths surrounding donation via @columbiacancer.bsky.social.
www.cancer.columbia.edu/news/breakin...
www.cancer.columbia.edu/news/breakin...
Breaking Down 10 Myths About Bone Marrow Donation for Blood Cancer Awareness Month
Dr. Aaron Viny shines a light on the lifesaving role of transplants in treating blood cancers and addresses some of the most persistent myths surrounding donation.
www.cancer.columbia.edu
October 1, 2025 at 12:20 AM
Thanks @cancerdynamics.bsky.social for highlighting this interview with @columbiacancer.bsky.social for Blood Cancer Awareness Month and our work in @cohesinlab
Reposted
🚨 Excited to share our new preprint: Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome. This work was led by Columbia VP&S MD student Varun Sudunagunta (‼️ Program Directors: Varun is applying to IM residencies this year!) www.biorxiv.org/content/10.1...
Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome
The transcription factor GATA1 has pleiotropic hematopoietic functions, particularly in erythroid and megakaryocytic ontogeny. While mechanistic investigations have uncovered many facets of GATA1 biol...
www.biorxiv.org
September 22, 2025 at 2:29 PM
🚨 Excited to share our new preprint: Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome. This work was led by Columbia VP&S MD student Varun Sudunagunta (‼️ Program Directors: Varun is applying to IM residencies this year!) www.biorxiv.org/content/10.1...
Can’t wait to read it John!
August 28, 2025 at 11:43 AM
Can’t wait to read it John!
Reposted
Educational Session: “Dysregulation of nuclear topology in cancer: Clinical implications and emerging mechanisms”
Presenter:
@thedoctorisvin.bsky.social
April 25, 2025, 3:30 PM - 3:50 PM CST/ 4:30 PM - 4:50 PM EST
Presenter:
@thedoctorisvin.bsky.social
April 25, 2025, 3:30 PM - 3:50 PM CST/ 4:30 PM - 4:50 PM EST
April 25, 2025 at 2:14 PM
Educational Session: “Dysregulation of nuclear topology in cancer: Clinical implications and emerging mechanisms”
Presenter:
@thedoctorisvin.bsky.social
April 25, 2025, 3:30 PM - 3:50 PM CST/ 4:30 PM - 4:50 PM EST
Presenter:
@thedoctorisvin.bsky.social
April 25, 2025, 3:30 PM - 3:50 PM CST/ 4:30 PM - 4:50 PM EST
If you’re at @theaacr.bsky.social don’t miss today’s session on 3D Topology & Cancer featuring giants of the field: Jane Skok @nyulangone.bsky.social & Brad Cairns @utah.edu
Imposter syndrome at an all time high! 😬
Proud to represent @cohesinlab.bsky.social @columbiacancer.bsky.social #AACR25
Imposter syndrome at an all time high! 😬
Proud to represent @cohesinlab.bsky.social @columbiacancer.bsky.social #AACR25
April 25, 2025 at 12:57 PM
If you’re at @theaacr.bsky.social don’t miss today’s session on 3D Topology & Cancer featuring giants of the field: Jane Skok @nyulangone.bsky.social & Brad Cairns @utah.edu
Imposter syndrome at an all time high! 😬
Proud to represent @cohesinlab.bsky.social @columbiacancer.bsky.social #AACR25
Imposter syndrome at an all time high! 😬
Proud to represent @cohesinlab.bsky.social @columbiacancer.bsky.social #AACR25
And is it just FLI1? We don’t think so! Actually a HUGE part of this mechanism coming into focus was it helps us unify our prior PU.1 finding and may explain your zebrafish runx1 data that has been the inspiration for so much of our work! journals.biologists.com/dev/article/...
Cohesin-dependent regulation of Runx genes
Runx transcription factors determine cell fate in many lineages. Maintaining balanced levels of Runx proteins is crucial, as deregulated expression leads to cancers and developmental disorders. We con...
journals.biologists.com
April 18, 2025 at 11:58 AM
And is it just FLI1? We don’t think so! Actually a HUGE part of this mechanism coming into focus was it helps us unify our prior PU.1 finding and may explain your zebrafish runx1 data that has been the inspiration for so much of our work! journals.biologists.com/dev/article/...
Nope! No change in my overall expression by RNA or protein—but a redistribution of the protein towards a much higher chromatin-bound fraction.
And we think this disordering of the FLI1 cistrome is a big part of the mechanism!
And we think this disordering of the FLI1 cistrome is a big part of the mechanism!
April 18, 2025 at 11:52 AM
Nope! No change in my overall expression by RNA or protein—but a redistribution of the protein towards a much higher chromatin-bound fraction.
And we think this disordering of the FLI1 cistrome is a big part of the mechanism!
And we think this disordering of the FLI1 cistrome is a big part of the mechanism!
Hey! Check out @drjanexu.bsky.social discussing @cohesinlab.bsky.social’s first preprint on @isehsociety.bsky.social simply blood preprint watch! www.simplyblood.org/2025/04/prep...
Preprint Watch: April
Welcome to our monthly Preprint Watch, where we highlight some of the most relevant preprints for the ISEH community! This month we cover so...
www.simplyblood.org
April 17, 2025 at 6:38 PM
Hey! Check out @drjanexu.bsky.social discussing @cohesinlab.bsky.social’s first preprint on @isehsociety.bsky.social simply blood preprint watch! www.simplyblood.org/2025/04/prep...
👇👇 Check out our first pre-print!
My very first post on 🦋. 1. Do you know that cohesin ring controls how transcription factor (TF) access chromatin? Excited to share my first piece of postdoctoral work where we investigate how Stag2 cohesin contributes to leukemia! 1/10. www.biorxiv.org/content/10.1....
April 10, 2025 at 6:24 PM
👇👇 Check out our first pre-print!