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Bharath Ananthasubramaniam @timelyscientist.bsky.social · May 31

Very interesting! Congraluations !
I saw an example of Fitz-Nagumo on github -- does this in general work also for large nonlinear systems?
Do you plans to have implementations in other languages (😉 Python?)

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · May 31

This is brilliant -- great work. Cant wait to try this out on my favorite feedback systems. Congratulations.

Nathanael Bosch @nathanaelbosch.de · May 30

🎉 My PhD dissertation is now online! Traditional ODE solvers compute a single solution estimate - Probabilistic solvers also tell you how reliable they are! In my PhD, I established them as a Flexible and Efficient Framework for Probabilistic Simulation and Inference.
📄 tinyurl.com/mt3sffb

🧵 1/6

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Reposted by Bharath Ananthasubramaniam

Society for Developmental Biology @socdevbio.bsky.social · May 30

🦋✨ #FluorescenceFriday meets developmental biology!
This glowing "butterfly" isn't an insect, it's a transverse section of a developing chicken gonad. When art meets science, even sex differentiation takes flight! Image taken by @martinestermann.bsky.social #ChickenModel #DevBio 🐥🔬

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · May 30

ML uncovers 24h rhythms in cancer 🕒🧬
Using COFE ☕, we reconstruct #circadian rhythms from human tumor biopsies across 11 #cancer types!
Turns out, tumor #clocks tick in a different timezone 🕰️💊
Got data? Let’s connect! 🤝
#AIforHealth #CircadianMedicine #oncology

PLOS Biology @plosbiology.org · May 28

Study of #circadian rhythms requires repeated sampling, but @timelyscientist.bsky.social &co present COFE, a #MachineLearning algorithm that enables virtual sampling of internal human tissues over time, revealing insights into circadian rhythms of human #tumors @plosbiology.org 🧪 plos.io/3Zx1Lt6

Workflow of Cyclic Ordering with Feature Extraction (COFE). Data without time labels are first optionally pre-filtered and then standardized. A novel cross-validation approach finds a value for the unknown sparsity parameter that guarantees good temporal ordering. Finally, COFE both assigns time labels to the samples and produces a list of rhythmic features in the data.

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · Apr 16

🚀 Thrilled to collaborate on this study led by Jihwan Myung, where we explored why organisms prefer #networks of autonomous #clocks over a single central #oscillator, proposing enhanced robustness, specialization, and adaptability.

👉 buff.ly/xhMsboJ

🙏 @dfg.de
#circadian #circadianmedicine

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · Mar 22

Enhance your experience of reading scholarly articles by taking advantage of Google Scholar's PDF viewer. Set it as your default PDF reader in Chrome to seamlessly access AI-created summaries for each section. Try it out here: buff.ly/LjX2K6d #research #tips

Do you know a better tool? Lemme know.

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · Mar 20

StuROPx bringt Studentinnen aus ganz Berlin zusammen ❤️! Danke an das #BUA und @humboldtuni.bsky.social für die Möglichkeit und Unterstützung!

humboldtuni.bsky.social @humboldtuni.bsky.social · Mar 12

🥼 #WirSindBUA: Der Chronobiologe Dr. Bharath Ananthasubramaniam ist nicht nur leidenschaftlicher Forscher, sondern unterrichtet auch gern. Im Programm StuROPx der @berlinualliance.bsky.social kann er beides miteinander verbinden. Wie das funktioniert, erklärt er 👉 www.hu-berlin.de/de/pr/wir-si...

Der Chronobiologe Dr. Bharath Ananthasubramaniam redet über das Programm StuROPx

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · Mar 19

🚨New preprint alert!🚨 Our latest study (with K. Padmanabhan & Y. Suzuki) on post-transcriptional #circadian regulation is out.

🔬 Key finding: #Clock proteins regulate #splicing of non-rhythmic transcripts too

Read it here 👉 buff.ly/xsanmqw

#omics #ScienceTwitter #Nanopore #multiomic

Circadian PERIOD proteins sculpt the mammalian alternative splicing landscape

Mammalian circadian oscillators are driven by a transcription-translation feedback loop where CLOCK:BMAL1 activity is repressed by the PER:CRY complex. While transcriptional regulation by PER is well…

buff.ly

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · Mar 14

Celebrate Pi Day and Holi (Festival of colors) by diving into the vibrant world of Penrose tiling! Combine the joy of coloring with your little ones with the beauty of #math and patterns (buff.ly/8RR568J).
It's a colorful and fun way to explore and learn! 🌈📐 #PiDay #HoliFestival #idm314 #STEM

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Bharath Ananthasubramaniam @timelyscientist.bsky.social · Mar 12

It's #BrainWeek! My journey in #circadian research began with the brain's internal #clock, initially thought to solely manage 24-hour body cycles. Now, we see it as a "first among equals," as most organs have their own #clocks. With regular rest & ample sunlight, the clock can be your #health ally.

Bharath Ananthasubramaniam @timelyscientist.bsky.social · Mar 4

This book argues that generalists excel over specialists in solving wicked real-world issues. Diverse perspectives and creativity are key when there’s no clear optimal solution. It’s changed my view as a teacher, researcher, and parent. Highly recommend! #Generalist #ProblemSolving #CreativeThinking