Tim Elliott
@timmunologist.bsky.social
Professor of Immuno-Oncology University of Oxford interested in antigen processing, T cells and interception vaccines for cancer.
Pinned
Tim Elliott
@timmunologist.bsky.social
· Nov 20
This is where I go to decompress. No Blackwell Oxford presence on bsky?
Reposted by Tim Elliott
🧬 Therapeutic cancer vaccines are back in focus! Advances in neo-antigen T cells, dendritic cell biology, and mRNA tech are paving the way for next-gen immunotherapy.
Read the Open Access review: https://bit.ly/4cefxGm
#CancerVaccines #Immunotherapy #mRNA #Oncology
Read the Open Access review: https://bit.ly/4cefxGm
#CancerVaccines #Immunotherapy #mRNA #Oncology
November 13, 2025 at 6:54 PM
🧬 Therapeutic cancer vaccines are back in focus! Advances in neo-antigen T cells, dendritic cell biology, and mRNA tech are paving the way for next-gen immunotherapy.
Read the Open Access review: https://bit.ly/4cefxGm
#CancerVaccines #Immunotherapy #mRNA #Oncology
Read the Open Access review: https://bit.ly/4cefxGm
#CancerVaccines #Immunotherapy #mRNA #Oncology
Reposted by Tim Elliott
🦠 DC3s in solid tumours can prime T cells and influence outcomes—boosting survival in some cancers, but promoting immunosuppression in others.
👉 https://bit.ly/3T2blRg
##Immunotherapy #CancerImmunology
👉 https://bit.ly/3T2blRg
##Immunotherapy #CancerImmunology
November 7, 2025 at 11:10 AM
🦠 DC3s in solid tumours can prime T cells and influence outcomes—boosting survival in some cancers, but promoting immunosuppression in others.
👉 https://bit.ly/3T2blRg
##Immunotherapy #CancerImmunology
👉 https://bit.ly/3T2blRg
##Immunotherapy #CancerImmunology
Reposted by Tim Elliott
🔬 First head-to-head comparison of nuclear imaging for tumour CD8⁺ T cells shows [⁸⁹Zr]Zr-anti-CD8-IgG2a(silent) & [⁸⁹Zr]Zr-OT-I track T-cell infiltration & migration, aiding immunotherapy strategies.
👉 https://bit.ly/4ncWCzv
##Immunotherapy #CD8Tcells #CancerResearch
👉 https://bit.ly/4ncWCzv
##Immunotherapy #CD8Tcells #CancerResearch
November 6, 2025 at 10:40 AM
🔬 First head-to-head comparison of nuclear imaging for tumour CD8⁺ T cells shows [⁸⁹Zr]Zr-anti-CD8-IgG2a(silent) & [⁸⁹Zr]Zr-OT-I track T-cell infiltration & migration, aiding immunotherapy strategies.
👉 https://bit.ly/4ncWCzv
##Immunotherapy #CD8Tcells #CancerResearch
👉 https://bit.ly/4ncWCzv
##Immunotherapy #CD8Tcells #CancerResearch
Reposted by Tim Elliott
Congratulations, Michael! 🎉
NEWS: Michael Bryan wins international award at Europe’s largest cancer conference
Congratulations to Michael, DPhil in Cancer Science student, on the Best Poster Prize in CNS Tumours at the 2025 ESMO Congress. @oxfordcancer.bsky.social
Congratulations to Michael, DPhil in Cancer Science student, on the Best Poster Prize in CNS Tumours at the 2025 ESMO Congress. @oxfordcancer.bsky.social
Michael Bryan wins international award at Europe’s largest cancer conference
Michael - who is a CRUK Oxford Centre DPhil in Cancer Science student, working in the Nuffield Department of Medicine's Centre of Immuno-oncology - has been awarded the Best Poster Prize in CNS Tumours at the 2025 European Society for Medical Oncology (ESMO) Congress.
www.medsci.ox.ac.uk
November 3, 2025 at 9:37 AM
Congratulations, Michael! 🎉
Agreed. Pipette for Power!
Totally agree that standard biological data isn't built for AI. We need to think strategically about how we build better, less biased richer datasets specifically for machine learning
The biggest challenge for AI in biology isn't just models, it's the data used to train them. Standard biological data isn't built for AI. To unlock generative AI for drug discovery, we must rethink how we generate and capture data. 1/
November 7, 2025 at 7:35 AM
Agreed. Pipette for Power!
Reposted by Tim Elliott
Offer cancer patients exercise on NHS major charity urges www.theguardian.com/society/2025...
Offer cancer patients exercise on NHS, major charity urges
Maggie’s says embedding activities such as yoga, tai chi and Nordic walking into care could boost chances of survival
www.theguardian.com
October 25, 2025 at 9:10 AM
Offer cancer patients exercise on NHS major charity urges www.theguardian.com/society/2025...
It seems someone removed the beautiful local multinational flag from the lamppost in East Oxford, but someone else has put up another one.
nextdoor.co.uk/p/8TdLxGqcS_...
nextdoor.co.uk/p/8TdLxGqcS_...
It seems someone removed the beautiful local multinational flag from the lamppost in East Oxford, but someone else has put up another one.
Join Nextdoor, an app for neighbourhoods where you can get local tips, buy and sell items, and more
nextdoor.co.uk
October 26, 2025 at 7:53 AM
It seems someone removed the beautiful local multinational flag from the lamppost in East Oxford, but someone else has put up another one.
nextdoor.co.uk/p/8TdLxGqcS_...
nextdoor.co.uk/p/8TdLxGqcS_...
Reposted by Tim Elliott
HuBIE: The Human Blood Immunome Encyclopedia Of TCRs and BCRs in Bloodstream Infections and Cancer https://www.biorxiv.org/content/10.1101/2025.10.22.678684v1
October 24, 2025 at 10:41 AM
Reposted by Tim Elliott
From CAR-NK cells to checkpoint inhibitors, Blunt & Khakoo review how boosting NK-cell function could transform cancer therapy.
🔓 Open access: https://bit.ly/4j8dKEW
#Immunotherapy #NKcells #CancerResearch
🔓 Open access: https://bit.ly/4j8dKEW
#Immunotherapy #NKcells #CancerResearch
October 22, 2025 at 3:30 PM
From CAR-NK cells to checkpoint inhibitors, Blunt & Khakoo review how boosting NK-cell function could transform cancer therapy.
🔓 Open access: https://bit.ly/4j8dKEW
#Immunotherapy #NKcells #CancerResearch
🔓 Open access: https://bit.ly/4j8dKEW
#Immunotherapy #NKcells #CancerResearch
Reposted by Tim Elliott
UK NK 2026 in Cardiff.
January 9th. Be there.
eventbrite.co.uk/e/uk-nk-confer…
Hosted by Rich Stanton, Ceri Fielding & Eddie Wang
January 9th. Be there.
eventbrite.co.uk/e/uk-nk-confer…
Hosted by Rich Stanton, Ceri Fielding & Eddie Wang
https://eventbrite.co.uk/e/uk-nk-confer…
October 23, 2025 at 8:53 AM
UK NK 2026 in Cardiff.
January 9th. Be there.
eventbrite.co.uk/e/uk-nk-confer…
Hosted by Rich Stanton, Ceri Fielding & Eddie Wang
January 9th. Be there.
eventbrite.co.uk/e/uk-nk-confer…
Hosted by Rich Stanton, Ceri Fielding & Eddie Wang
Reposted by Tim Elliott
Need funding to attend your next conference? 💡
The BSI Conference Travel Grants can cover your travel costs - UK (£500), Europe (£700), rest of world (£1,000).
The deadline is just over 1 week away (1 November), so submit your application soon! https://bit.ly/3U0jk2E
The BSI Conference Travel Grants can cover your travel costs - UK (£500), Europe (£700), rest of world (£1,000).
The deadline is just over 1 week away (1 November), so submit your application soon! https://bit.ly/3U0jk2E
October 23, 2025 at 10:00 AM
Need funding to attend your next conference? 💡
The BSI Conference Travel Grants can cover your travel costs - UK (£500), Europe (£700), rest of world (£1,000).
The deadline is just over 1 week away (1 November), so submit your application soon! https://bit.ly/3U0jk2E
The BSI Conference Travel Grants can cover your travel costs - UK (£500), Europe (£700), rest of world (£1,000).
The deadline is just over 1 week away (1 November), so submit your application soon! https://bit.ly/3U0jk2E
@witherslab.bsky.social going from strength to strength
In this weeks @oxcio.bsky.social seminar, our PostDoc Pascale presented her current progress on setting up #SingleCellSequencing experiments and their analysis for the @witherslab.bsky.social in Oxford! 🖥️💡🐭
Exciting!!!
Exciting!!!
October 24, 2025 at 6:17 AM
@witherslab.bsky.social going from strength to strength
Tick what? Many happy returns Felipe and well marked Anjum!
🤩CIO Cake Alert!! Anjum made this amazing lemon blueberry sponge cake for Felipe’s @galvez-cancino.bsky.social birthday from a TikTok recipe 🍰💙 But she promised to add it to our recipe collection making it truly generational-friendly!We’re so excited that homebaked cakes are back to CIO again 🎉
October 24, 2025 at 6:14 AM
Tick what? Many happy returns Felipe and well marked Anjum!
Reposted by Tim Elliott
4 decades of IO – Celebrating 40 years of SITC. In 2009, we had a record meeting attendance and abstract submission! Attend this year's 40th Anniversary Annual Meeting and be a part of the science. https://www.sitcancer.org/2025/home
October 23, 2025 at 3:15 PM
4 decades of IO – Celebrating 40 years of SITC. In 2009, we had a record meeting attendance and abstract submission! Attend this year's 40th Anniversary Annual Meeting and be a part of the science. https://www.sitcancer.org/2025/home
Reposted by Tim Elliott
Wonderful day celebrating Paul Nurse after he steps down from being the Director @crick.ac.uk. We are all very grateful to him for having created an amazing institute.
October 23, 2025 at 8:35 PM
Wonderful day celebrating Paul Nurse after he steps down from being the Director @crick.ac.uk. We are all very grateful to him for having created an amazing institute.
@blackwellbooks.bsky.social please start posting
July 20, 2025 at 6:42 AM
@blackwellbooks.bsky.social please start posting
Reposted by Tim Elliott
Great to see our work on preventive cancer vaccines, including LungVax, featured in this issue!
@oxfordcancer.bsky.social @sarahblagden.bsky.social @timmunologist.bsky.social
@oxfordcancer.bsky.social @sarahblagden.bsky.social @timmunologist.bsky.social
Progress in the fight against the disease has been slow, steady—and remarkable. Long may that continue
The world is winning the war on cancer
Progress has been remarkable. Death rates are down substantially, and are likely to fall further
econ.st
July 19, 2025 at 9:52 AM
Great to see our work on preventive cancer vaccines, including LungVax, featured in this issue!
@oxfordcancer.bsky.social @sarahblagden.bsky.social @timmunologist.bsky.social
@oxfordcancer.bsky.social @sarahblagden.bsky.social @timmunologist.bsky.social
Reposted by Tim Elliott
Join us for our DPhil in Cancer Science Open Day on Tuesday 2nd September at 12:30pm to find out how a DPhil can be the next step in your cancer research career development!
Register via our Eventbrite link before 1st Sept⬇️ @oncology.ox.ac.uk @medsci.ox.ac.uk
www.eventbrite.co.uk/e/university...
Register via our Eventbrite link before 1st Sept⬇️ @oncology.ox.ac.uk @medsci.ox.ac.uk
www.eventbrite.co.uk/e/university...
University of Oxford - DPhil in Cancer Science Open Day
Join the Virtual DPhil in Cancer Science Open Day to hear more about Oxford’s world-leading research training
www.eventbrite.co.uk
July 18, 2025 at 3:16 PM
Join us for our DPhil in Cancer Science Open Day on Tuesday 2nd September at 12:30pm to find out how a DPhil can be the next step in your cancer research career development!
Register via our Eventbrite link before 1st Sept⬇️ @oncology.ox.ac.uk @medsci.ox.ac.uk
www.eventbrite.co.uk/e/university...
Register via our Eventbrite link before 1st Sept⬇️ @oncology.ox.ac.uk @medsci.ox.ac.uk
www.eventbrite.co.uk/e/university...
Looking forward to talking about #cancervaccines to *all* @CRUK research and innovation staff this afternoon at their fabulous away-day. Actually I’m a bit nervous😬
July 17, 2025 at 11:26 AM
Looking forward to talking about #cancervaccines to *all* @CRUK research and innovation staff this afternoon at their fabulous away-day. Actually I’m a bit nervous😬
Reposted by Tim Elliott
Amazing news for our Institute @kiroxford.bsky.social @ox.ac.uk 🎉🍾😀 ! Looking forward to working with our @manchester.ac.uk colleagues to understand better how envrionmental determinants drive chronic inflammatory diseases !
Huge news! A £50M MRC CoRE will bring together Manchester & Oxford to study how environmental exposures cause chronic inflammatory disease.
The CoRE will be Directed by Prof Judi Allen (Manchester) & co-Directed by Prof Dame Fiona Powrie, Director of the KIR.
www.kennedy.ox.ac.uk/news/new-ps5...
The CoRE will be Directed by Prof Judi Allen (Manchester) & co-Directed by Prof Dame Fiona Powrie, Director of the KIR.
www.kennedy.ox.ac.uk/news/new-ps5...
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A new Medical Research Council Centre of Research Excellence (MRC CoRE) will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases, such as asthma, ...
www.kennedy.ox.ac.uk
July 16, 2025 at 9:15 PM
Amazing news for our Institute @kiroxford.bsky.social @ox.ac.uk 🎉🍾😀 ! Looking forward to working with our @manchester.ac.uk colleagues to understand better how envrionmental determinants drive chronic inflammatory diseases !
Reposted by Tim Elliott
Targeting monocyte dynamics in MS?
In Immunotherapy Advances, Bibi et al. explore how shifting monocytes from inflammatory to reparative states may reshape MS treatment strategies.
📘 https://bit.ly/3EXOfaV
##MS #Monocytes #Neuroinflammation
In Immunotherapy Advances, Bibi et al. explore how shifting monocytes from inflammatory to reparative states may reshape MS treatment strategies.
📘 https://bit.ly/3EXOfaV
##MS #Monocytes #Neuroinflammation
July 15, 2025 at 1:00 PM
Targeting monocyte dynamics in MS?
In Immunotherapy Advances, Bibi et al. explore how shifting monocytes from inflammatory to reparative states may reshape MS treatment strategies.
📘 https://bit.ly/3EXOfaV
##MS #Monocytes #Neuroinflammation
In Immunotherapy Advances, Bibi et al. explore how shifting monocytes from inflammatory to reparative states may reshape MS treatment strategies.
📘 https://bit.ly/3EXOfaV
##MS #Monocytes #Neuroinflammation
Reposted by Tim Elliott
New research by Rui Zhao et al. shows that high anti-drug antibody (ADA) levels after 3 cycles of camrelizumab are linked to shorter survival in patients with advanced solid cancers.
📉 Higher ADA = lower drug levels = worse outcomes.
🔗 https://bit.ly/461mc5B
##Immunotherapy #CancerResearch
📉 Higher ADA = lower drug levels = worse outcomes.
🔗 https://bit.ly/461mc5B
##Immunotherapy #CancerResearch
July 14, 2025 at 12:40 PM
New research by Rui Zhao et al. shows that high anti-drug antibody (ADA) levels after 3 cycles of camrelizumab are linked to shorter survival in patients with advanced solid cancers.
📉 Higher ADA = lower drug levels = worse outcomes.
🔗 https://bit.ly/461mc5B
##Immunotherapy #CancerResearch
📉 Higher ADA = lower drug levels = worse outcomes.
🔗 https://bit.ly/461mc5B
##Immunotherapy #CancerResearch
Reposted by Tim Elliott
🧬 Better understanding of immune rejection and evasion is setting the stage for next-gen therapies.
Elizabeth Simpson reviews how foundational immunology is reshaping transplant and cancer treatment.
📖 https://bit.ly/44N141N
##TransplantImmunology #Immunotherapy
Elizabeth Simpson reviews how foundational immunology is reshaping transplant and cancer treatment.
📖 https://bit.ly/44N141N
##TransplantImmunology #Immunotherapy
July 4, 2025 at 5:14 PM
🧬 Better understanding of immune rejection and evasion is setting the stage for next-gen therapies.
Elizabeth Simpson reviews how foundational immunology is reshaping transplant and cancer treatment.
📖 https://bit.ly/44N141N
##TransplantImmunology #Immunotherapy
Elizabeth Simpson reviews how foundational immunology is reshaping transplant and cancer treatment.
📖 https://bit.ly/44N141N
##TransplantImmunology #Immunotherapy
Reposted by Tim Elliott
🧩 Antigen presentation is complex - but imaging is bringing clarity.
@doreenlau.bsky.social & @timmunologist.bsky.social review how advanced imaging illuminates T-cell–APC interactions, peptide-MHC dynamics, and more in cancer immunity.
📖 https://bit.ly/3TkIasN
##CancerImmunology
@doreenlau.bsky.social & @timmunologist.bsky.social review how advanced imaging illuminates T-cell–APC interactions, peptide-MHC dynamics, and more in cancer immunity.
📖 https://bit.ly/3TkIasN
##CancerImmunology
July 6, 2025 at 1:27 PM
🧩 Antigen presentation is complex - but imaging is bringing clarity.
@doreenlau.bsky.social & @timmunologist.bsky.social review how advanced imaging illuminates T-cell–APC interactions, peptide-MHC dynamics, and more in cancer immunity.
📖 https://bit.ly/3TkIasN
##CancerImmunology
@doreenlau.bsky.social & @timmunologist.bsky.social review how advanced imaging illuminates T-cell–APC interactions, peptide-MHC dynamics, and more in cancer immunity.
📖 https://bit.ly/3TkIasN
##CancerImmunology
Reposted by Tim Elliott
A high-affinity TCRxCD3 bispecific (ImmTAC®) efficiently redirects T cells to kill PRAME+ tumor cells, even at low epitope density. Combination with anti-PD-1 restores activity in exhausted T cells.
One of the most read articles in ITA: https://bit.ly/40o5kT8
##immunology
One of the most read articles in ITA: https://bit.ly/40o5kT8
##immunology
July 10, 2025 at 4:49 PM
A high-affinity TCRxCD3 bispecific (ImmTAC®) efficiently redirects T cells to kill PRAME+ tumor cells, even at low epitope density. Combination with anti-PD-1 restores activity in exhausted T cells.
One of the most read articles in ITA: https://bit.ly/40o5kT8
##immunology
One of the most read articles in ITA: https://bit.ly/40o5kT8
##immunology