Lightnews — Scholar-powered news

Reposted by Charlotte Capitanchik

Standplaats Kraków @standplaatskrk.pl · 1d

an internet explorer window against the windows xp background with a geocities.com address in the bar "/Kingofkings".

The page displayed is a broken image on a black background, and the sentence: "My name is Ozymandias, King of Kings; Look upon my Works, ye Mighty, and despair!"

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Charlotte Capitanchik @tinycaptain.bsky.social · 8d

If I had to do a second PhD it would for sure be this one! So exciting!

Greg Findlay @gregfindlay.bsky.social · 8d

🚨 Applications to the Crick PhD programme are now open!

We are pleased to be recruiting this year. 👇

www.crick.ac.uk/careers-stud...

Findlay Lab | Developing novel genome editing methods to test human genetic variants at scale

www.crick.ac.uk

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Reposted by Charlotte Capitanchik

Tim Onion @bencollins.bsky.social · 17d

So cool they discovered the cause of autism on basically day they guessed they would. I’m also glad they are withholding this information for a few days to prep for a WrestleMania-style announcement. This is how science works.

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Charlotte Capitanchik @tinycaptain.bsky.social · 17d

Like & share our new promo vid for Flow.bio! Capturing just a little bit of that bioinformatics trauma 🫠 www.youtube.com/watch?v=MR-R...

Flow

Flow.bio

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Reposted by Charlotte Capitanchik

John Choiniere @johnchoiniere.bsky.social · 17d

Acetaminophen/paracetamol use in pregnancy doesn't cause autism, no matter what RFK says this week. This is not an unsettled question. Evidence summarized here: sciencebasedmedicine.org/tylenol-and-...

Tylenol and Autism

Earlier this year, HHS secretary RFK Jr. predicted that, "By September, we will know what has caused the autism epidemic and we'll be able to eliminate those exposures." Scientists have been researc

sciencebasedmedicine.org

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Reposted by Charlotte Capitanchik

Oded Rechavi @odedrechavi.bsky.social · 20d

Only single cell sequencing of the all these post docs will reveal why

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Charlotte Capitanchik @tinycaptain.bsky.social · Sep 2

Congratulations to @bencekover.bsky.social for winning the best talk prize for schooling us all on best practises in mass scRNA-Seq data integration #Londonomics2025

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Charlotte Capitanchik @tinycaptain.bsky.social · Sep 2

Can’t thank our career mentors enough for the great discussions in our mentorship session @margaridamcm.bsky.social @kristinaulicna.bsky.social @gavinpaulkelly.bsky.social and Mara Tatari 💪#Londonomics2025

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Charlotte Capitanchik @tinycaptain.bsky.social · Sep 2

In the afternoon we had an excellent talk about AlphaMissense and AlphaGenome from @avsecz.bsky.social who generously allowed us to heckle him during the talk, answering all our questions!

Charlotte Capitanchik @tinycaptain.bsky.social · Sep 2

In the morning we enjoyed 11 short talks from computational biology ECRs - I especially liked @saniyakhullar.bsky.social’s talk on incorporating prior PPI knowledge into gene regulatory network inference #londonomics2025

Charlotte Capitanchik @tinycaptain.bsky.social · Sep 2

Had such a great time at #Londonomics2025 today - excellent talks and discussions - thank you to everyone who came along and shared their ideas with us.

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Charlotte Capitanchik @tinycaptain.bsky.social · Sep 1

Sounds like a wonderful position

Manuel Irimia @mirimiam.bsky.social · Jul 23

🚨🚨🚨

Please RT!

We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.

Deadline: 30/09/25👇

www.upf.edu

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Charlotte Capitanchik @tinycaptain.bsky.social · Aug 18

RUN, DON'T WALK to sign up for the londonomics symposium! we gotta order the sandwiches soon, so grab your ticket while you can! come hear about AlphaGenome & other great omics work, get career advice and hang out with us, it'll be so great i promise register.oxfordabstracts.com/event/75604?...

Oxford Abstracts Delegate Registration

register.oxfordabstracts.com

Reposted by Charlotte Capitanchik

Will Ratcliff @wcratcliff.bsky.social · Aug 12

Not sure how many scientists here have tried Claude Code or similar command line coding assistants. I had a complicated family property tax problem that was best solved by a brute force Monte Carlo simulation approach, so I spent a few days coding up and analyzing a model with Claude Code.

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Charlotte Capitanchik @tinycaptain.bsky.social · Aug 7

Did GPT-5 make this graph?

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Charlotte Capitanchik @tinycaptain.bsky.social · Jul 29

Registration here ➡️ register.oxfordabstracts.com/event/75604?...

Oxford Abstracts Delegate Registration

register.oxfordabstracts.com

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Charlotte Capitanchik @tinycaptain.bsky.social · Jul 29

Excited for this! Please do come and present your work :D

londonomics.bsky.social @londonomics.bsky.social · Jul 29

Are you an Early Career Researcher in bioinformatics? Then this symposium is for you 💡

Join us for a day of talks, networking and career discussions. Present your work to get fresh new ideas and the chance to win prizes 💸

Featuring @avsecz.bsky.social of Google DeepMind as our keynote speaker⚡️

Reposted by Charlotte Capitanchik

Jay Brito Querido @jbquerido.bsky.social · Jul 22

This work is the result of a fantastic collaboration between my lab at the University of Michigan, Mitchell Guttman lab at Caltech, and Marko Jovanovic lab at Columbia University.
www.cell.com/cell/fulltex...
#Ribosomes #Science #CryoEM #RNA

SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress

SPIDR, a massively multiplexed method that simultaneously maps dozens of RNA-binding proteins to their RNA targets at single-nucleotide resolution, uncovers new RNA-protein interactions and provides c...

www.cell.com

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Charlotte Capitanchik @tinycaptain.bsky.social · Jul 21

😂

Dr Abeba Birhane @abeba.bsky.social · Jul 21

this is the very technology orgs like the UN is adopting to "solve" gender inequity

Amy Diehl, Ph.D. @amydiehl.bsky.social · Jul 20

Study finds A.I. LLMs advise women to ask for lower salaries than men. When prompted w/ a user profile of same education, experience & job role, differing only by gender, ChatGPT advised the female applicant to request $280K salary; Male applicant=$400K.
thenextweb.com/news/chatgpt...

Reposted by Charlotte Capitanchik

UCSC Genome Browser @genomebrowser.bsky.social · Jul 16

New ENCODE4 long-read RNA-seq transcripts track for hg38 and mm10. Triplets (e.g. [1,1,3]) indicate start site, exon combination, and stop site for each transcript. Enrichment scores show how these change across tissue and cell line samples.

Read more: genome.ucsc.edu/gold...

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Reposted by Charlotte Capitanchik

🎃nisillos @onisillos.bsky.social · Jun 30

"It is not just that LLM’s fail to induce proper world models of chess. It’s that they never induce proper worlds of anything. Everything that they do is through mimicry, rather than abstracted cognition across proper world models."

garymarcus.substack.com/p/generative...

Generative AI’s crippling and widespread failure to induce robust models of the world

LLM failures to reason, as documented in Apple’s Illusion of Thinking paper, are really only part of a much deeper problem

garymarcus.substack.com

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Charlotte Capitanchik @tinycaptain.bsky.social · Jun 23

Totally agree!! "How to make the next PDB" This is exactly what we've attempted to do for functional genomics with flow.bio www.biorxiv.org/content/10.1...

Isabelle Zane @isabellease.bsky.social · Jun 23

Michael Bronstein @mmbronstein.bsky.social at #AIxBio

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Charlotte Capitanchik @tinycaptain.bsky.social · Jun 13

@simranolak.bsky.social 🙌

Charlotte Capitanchik @tinycaptain.bsky.social · Jun 13

incredible work by an incredible scientist (and friend)! very beautiful figures too www.cell.com/cell-systems...

The molecular landscape of cellular metal ion biology

Aulakh et al. systematically investigated how metal ion availability impacts yeast biochemistry. Their metallomic, proteomic, and genetic screens reveal the widespread metal concentration dependence o...

www.cell.com

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Reposted by Charlotte Capitanchik

Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · May 13

"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.

Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."

David Malakoff @davidmalakoff.bsky.social · May 13

Another scoop from Jeff Mervis (@policyhound.bsky.social): NSF's ~1400 grant terminations have disproportionately affected PIs from groups underrepresented in science: women, racial & ethnic minorities, & those with disabilities. 1/3
www.science.org/content/arti...

Trump officials take steps toward a radically different NSF

Efforts to shrink staff, budget, and focus have alarmed members of Congress

www.science.org

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