Vanderbilt Center for Structural Biology
@vanderbiltcsb.bsky.social
Vanderbilt Center for Structural Biology - Research dedicated to determining the 3D structure of biological macromolecules at or near atomic resolution.
www.vanderbilt.edu/csb
www.vanderbilt.edu/csb
Pinned
The external speakers are set and ready to navigate the intersection of #AI & #StructBio for the Bridging Atoms and Algorithms: A Symposium on AI and Structural Biology.
🗓️Tuesday & Wednesday, March 17–18, 2026
🏫Campus of Vanderbilt University
bit.ly/4ldBOaz
🗓️Tuesday & Wednesday, March 17–18, 2026
🏫Campus of Vanderbilt University
bit.ly/4ldBOaz
Kate Clowes Moster, of the Chuck Sanders lab, is the winner of the 2026 Dr. Anne Karpay Award in Structural Biology!
bit.ly/2026-karpay
@vubasicsciences.bsky.social @vanderbiltvicb.bsky.social @vandybiomed.bsky.social
bit.ly/2026-karpay
@vubasicsciences.bsky.social @vanderbiltvicb.bsky.social @vandybiomed.bsky.social
November 14, 2025 at 1:57 PM
Kate Clowes Moster, of the Chuck Sanders lab, is the winner of the 2026 Dr. Anne Karpay Award in Structural Biology!
bit.ly/2026-karpay
@vubasicsciences.bsky.social @vanderbiltvicb.bsky.social @vandybiomed.bsky.social
bit.ly/2026-karpay
@vubasicsciences.bsky.social @vanderbiltvicb.bsky.social @vandybiomed.bsky.social
Reposted by Vanderbilt Center for Structural Biology
@vanderbilt.edu and Ancora Innovations continue their collaboration to advance translational research and health care innovation.
VICB recognizes the importance of partnerships that connect discovery with real-world impact.
Learn more: bit.ly/47T1ZOP
VICB recognizes the importance of partnerships that connect discovery with real-world impact.
Learn more: bit.ly/47T1ZOP
Vanderbilt’s Ancora Partnership: A collaborative journey toward health care innovation
Since the inception of the Ancora Innovations partnership in 2018, Vanderbilt and Deerfield Management have enjoyed a robust collaboration. Deerfield’s commitment includes significant support for adva...
bit.ly
October 29, 2025 at 3:48 PM
@vanderbilt.edu and Ancora Innovations continue their collaboration to advance translational research and health care innovation.
VICB recognizes the importance of partnerships that connect discovery with real-world impact.
Learn more: bit.ly/47T1ZOP
VICB recognizes the importance of partnerships that connect discovery with real-world impact.
Learn more: bit.ly/47T1ZOP
Reposted by Vanderbilt Center for Structural Biology
🧬 🪦 Dean emeritus Larry Marnett, Mike Goodman (staff scientist in the Sanders lab), and senior advisor to the dean Chuck Sanders paid their annual visit to the grave of Oswald Avery, the scientist “best known for his discovery that DNA serves as genetic material.
profiles.nlm.nih.gov/spotlight/cc
profiles.nlm.nih.gov/spotlight/cc
November 1, 2025 at 5:15 PM
🧬 🪦 Dean emeritus Larry Marnett, Mike Goodman (staff scientist in the Sanders lab), and senior advisor to the dean Chuck Sanders paid their annual visit to the grave of Oswald Avery, the scientist “best known for his discovery that DNA serves as genetic material.
profiles.nlm.nih.gov/spotlight/cc
profiles.nlm.nih.gov/spotlight/cc
Reposted by Vanderbilt Center for Structural Biology
A recent study from ZJ Yang Lab examines how structural flexibility contributes to cold adaptation in cellulases.
Read more:
www.vanderbilt.edu/csb/2025/10/...
Read more:
www.vanderbilt.edu/csb/2025/10/...
Sometimes space is a good thing: uncovering the structural determinants of cold adaptation in cellulases
By Cameron I. Cohen Cellulases are enzymes responsible for the hydrolysis of glycosidic bonds in cellulose, a polysaccharide which serves as the main structural material in plant cell walls. The effic...
www.vanderbilt.edu
November 3, 2025 at 3:14 PM
A recent study from ZJ Yang Lab examines how structural flexibility contributes to cold adaptation in cellulases.
Read more:
www.vanderbilt.edu/csb/2025/10/...
Read more:
www.vanderbilt.edu/csb/2025/10/...
Reposted by Vanderbilt Center for Structural Biology
Some of our leaders attended the 2025 Biomedical Research Training Conference, hosted by the Association of American Medical Colleges’ Group on Research, Education and Training. They shared Vanderbilt's innovative approaches to trainee recruiting, mentoring, and more! 👉 news.vumc.org/2025/10/08/v...
Vanderbilt leaders in filling the biomedical research pipeline shine at national meeting
VUSM played a major role in a national conference that showcased the critical need to train biomedical researchers to advance medical care.
news.vumc.org
October 21, 2025 at 5:30 PM
Some of our leaders attended the 2025 Biomedical Research Training Conference, hosted by the Association of American Medical Colleges’ Group on Research, Education and Training. They shared Vanderbilt's innovative approaches to trainee recruiting, mentoring, and more! 👉 news.vumc.org/2025/10/08/v...
Reposted by Vanderbilt Center for Structural Biology
Colleagues and former trainees gathered to honor Dr. Larry J. Marnett, Dean Emeritus, Distinguished Professor, and founding leader of the Vanderbilt Institute of Chemical Biology (VICB).
Celebrating 50 years.
🔗 Read more: bit.ly/4nhbP2w
@vanderbilt.edu @vubasicsciences.bsky.social #wednesday
Celebrating 50 years.
🔗 Read more: bit.ly/4nhbP2w
@vanderbilt.edu @vubasicsciences.bsky.social #wednesday
From lab to legacy: Marnett’s trainees gather to toast a life in science and service
In a heartwarming tribute to a remarkable career, more than 70 of his former graduate students and postdoctoral scholars recently traveled from across the globe for a three-day festivity on Oct. 3–5 t...
bit.ly
October 22, 2025 at 6:09 PM
Colleagues and former trainees gathered to honor Dr. Larry J. Marnett, Dean Emeritus, Distinguished Professor, and founding leader of the Vanderbilt Institute of Chemical Biology (VICB).
Celebrating 50 years.
🔗 Read more: bit.ly/4nhbP2w
@vanderbilt.edu @vubasicsciences.bsky.social #wednesday
Celebrating 50 years.
🔗 Read more: bit.ly/4nhbP2w
@vanderbilt.edu @vubasicsciences.bsky.social #wednesday
Congrats to @bpbrown.bsky.social on his single-author paper recently published in @pnas.org! Read more on how he tackles a key roadblock for AI in drug discovery
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social
Vanderbilt scientist tackles key roadblock for AI in drug discovery
Vanderbilt’s Dr. Benjamin P. Brown is improving the way the field of drug discovery creates machine learning algorithms to predict a protein’s interactions with a small molecule. These improvements br...
medschool.vanderbilt.edu
October 20, 2025 at 3:28 PM
Congrats to @bpbrown.bsky.social on his single-author paper recently published in @pnas.org! Read more on how he tackles a key roadblock for AI in drug discovery
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social
Reposted by Vanderbilt Center for Structural Biology
@caltech.edu doctoral student Vida Robertson highlighted a publication from Jens Meiler, from @vanderbilt.edu, who describes using Rosetta to design antibiotic peptides called lanthipeptides with antibiotic properties.
Read more here: buff.ly/d6k8HvB
#SBGrid #NMR #ProteinDesign
Read more here: buff.ly/d6k8HvB
#SBGrid #NMR #ProteinDesign
Investigating antibiotic characteristics from the computer
SBGrid member Jens Meiler uses Rosetta to design antibiotic peptides called lanthipeptides with antibiotic properties.
buff.ly
October 3, 2025 at 4:03 PM
@caltech.edu doctoral student Vida Robertson highlighted a publication from Jens Meiler, from @vanderbilt.edu, who describes using Rosetta to design antibiotic peptides called lanthipeptides with antibiotic properties.
Read more here: buff.ly/d6k8HvB
#SBGrid #NMR #ProteinDesign
Read more here: buff.ly/d6k8HvB
#SBGrid #NMR #ProteinDesign
Reposted by Vanderbilt Center for Structural Biology
Open science! 📖 Notes from the first @andolab.bsky.social beamtime for the @diffuseproject.bsky.social - check it out!
diffuse.science/logbook/beam...
diffuse.science/logbook/beam...
2025-09-24 @ CHESS 7b2 - Logbook
A logbook for the Diffuse Project
diffuse.science
September 27, 2025 at 3:04 AM
Open science! 📖 Notes from the first @andolab.bsky.social beamtime for the @diffuseproject.bsky.social - check it out!
diffuse.science/logbook/beam...
diffuse.science/logbook/beam...
Reposted by Vanderbilt Center for Structural Biology
¡No olviden solicitar a nuestro premio de viaje para asistir a la conferencia @biophysicalsoc.bsky.social #BPS2026! Vean más detalles de cómo solicitar en el fondo 👇
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Don't forget to apply to our travel award to attend the #BPS2026 Meeting! See application instructions below 👇
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Don't forget to apply to our travel award to attend the #BPS2026 Meeting! See application instructions below 👇
🚨🚨🚨ANUNCIO IMPORTANTE 🚨🚨🚨
¡Tenemos un premio de viaje para asistir a #BPS2026 @biophysicalsoc.bsky.social en San Francisco!
Sigue estos pasos:
➡️ Solicita al BPS Travel Award (www.biophysics.org/2026meeting/...)
➡️ Marca la opción para ser considerado para el premio de SoBLa
¡Solicita hoy! ✅
¡Tenemos un premio de viaje para asistir a #BPS2026 @biophysicalsoc.bsky.social en San Francisco!
Sigue estos pasos:
➡️ Solicita al BPS Travel Award (www.biophysics.org/2026meeting/...)
➡️ Marca la opción para ser considerado para el premio de SoBLa
¡Solicita hoy! ✅
September 29, 2025 at 2:37 PM
¡No olviden solicitar a nuestro premio de viaje para asistir a la conferencia @biophysicalsoc.bsky.social #BPS2026! Vean más detalles de cómo solicitar en el fondo 👇
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Don't forget to apply to our travel award to attend the #BPS2026 Meeting! See application instructions below 👇
---
Don't forget to apply to our travel award to attend the #BPS2026 Meeting! See application instructions below 👇
With a new collaboration called diffUSE, the @stephanieaw.bsky.social lab is helping to advance our understanding of protein motion, leading to a new paradigm in dynamic structural biology.
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...
September 26, 2025 at 2:30 PM
With a new collaboration called diffUSE, the @stephanieaw.bsky.social lab is helping to advance our understanding of protein motion, leading to a new paradigm in dynamic structural biology.
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...
@vubasicsciences.bsky.social
medschool.vanderbilt.edu/basic-scienc...
Congratulations to @dougkojetin.bsky.social!
🎉 Congratulations to William Tansey and Douglas Kojetin on their new leadership roles at Vanderbilt-Ingram Cancer Center!
These leaders are stepping up to drive innovation, enhance collaboration, and accelerate cancer research at Vanderbilt. 🧬✨
Learn more 👉 news.vumc.org/2025/09/10/v...
These leaders are stepping up to drive innovation, enhance collaboration, and accelerate cancer research at Vanderbilt. 🧬✨
Learn more 👉 news.vumc.org/2025/09/10/v...
Vanderbilt-Ingram Cancer Center names associate directors and new program leaders
Four high-profile researchers at Vanderbilt-Ingram Cancer Center have assumed new and varied leadership roles.
news.vumc.org
September 25, 2025 at 8:55 PM
Congratulations to @dougkojetin.bsky.social!
Reposted by Vanderbilt Center for Structural Biology
August's software push includes updates to over 20 titles including ACPyPE, AlphaPulldown, Boltz, CCP-EM, ChimeraX, CryoDRGN, Doppio, fpocket, Geneious, Gnuplot, ISOLDE, IsoNet, MDAnalysis, MemBrain-seg, Napari, NMRFx-Analyst, and many more.
More information here: buff.ly/KhZw2Tb
#SBGrid #Software
More information here: buff.ly/KhZw2Tb
#SBGrid #Software
SBGrid Consortium - Software Updates
The SBGrid Consortium is an innovative global research computing group operated out of Harvard Medical School. SBGrid provides the global structural biology community with support for research…
buff.ly
September 10, 2025 at 4:03 PM
August's software push includes updates to over 20 titles including ACPyPE, AlphaPulldown, Boltz, CCP-EM, ChimeraX, CryoDRGN, Doppio, fpocket, Geneious, Gnuplot, ISOLDE, IsoNet, MDAnalysis, MemBrain-seg, Napari, NMRFx-Analyst, and many more.
More information here: buff.ly/KhZw2Tb
#SBGrid #Software
More information here: buff.ly/KhZw2Tb
#SBGrid #Software
Reposted by Vanderbilt Center for Structural Biology
Want to get involved, share your ideas, or just stay in the loop with email updates? Let us know here: forms.gle/37pK2smABwbg...
Diffuse Project Interest Form
Interested in the Diffuse Project? Please provide your information to help us shape community engagement and potentially direct you to the right project member.
forms.gle
August 14, 2025 at 7:01 PM
Want to get involved, share your ideas, or just stay in the loop with email updates? Let us know here: forms.gle/37pK2smABwbg...
Recent computational work on cold-active bidomain cellulase from the @mutexazjy.bsky.social lab published in Protein Science: "Linker‐mediated domain separation enhances cold adaptation in cellulases"
@vuartsci.bsky.social @vanderbiltvicb.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
@vuartsci.bsky.social @vanderbiltvicb.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Linker‐mediated domain separation enhances cold adaptation in cellulases
Cold-adapted cellulases have the potential to reduce energy demands in industrial processes by enabling efficient cellulose saccharification at lower temperatures. However, the structural basis of co...
onlinelibrary.wiley.com
August 15, 2025 at 8:20 PM
Recent computational work on cold-active bidomain cellulase from the @mutexazjy.bsky.social lab published in Protein Science: "Linker‐mediated domain separation enhances cold adaptation in cellulases"
@vuartsci.bsky.social @vanderbiltvicb.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
@vuartsci.bsky.social @vanderbiltvicb.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Cool news from the @stephanieaw.bsky.social lab!
We are thrilled to be part of Project Diffuse, building infrastructure for the dynamic future of structural biology.
We are helping to lead the modeling and encoding efforts of this project, including designing infrastructure that allows AI to learn from the full complexity of experimental data.
We are helping to lead the modeling and encoding efforts of this project, including designing infrastructure that allows AI to learn from the full complexity of experimental data.
What’s the next PDB? Maybe it’s …the PDB.
We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇
www.diffuse.science
We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇
www.diffuse.science
August 15, 2025 at 8:19 PM
Cool news from the @stephanieaw.bsky.social lab!
🎊Congratulations to CSB researcher Yi Ren on her promotion to Associate Professor of Biochemistry! 🥂
🎉 Congrats to the faculty members in our school on their recent appointments and promotions! 👏🏻👏🏼👏🏽👏🏾👏🏿 medschool.vanderbilt.edu/basic-sciences/2025/07/16/celebrating-appointments-and-promotions-in-the-school-of-medicine-basic-sciences-april-june-2025/
Celebrating appointments and promotions in the School of Medicine Basic Sciences: April–June 2025
Congratulations to our School of Medicine Basic Sciences members who were promoted or received new appointments between April and June 2025. These individuals significantly enrich our pursuit of pa…
medschool.vanderbilt.edu
July 21, 2025 at 12:44 PM
🎊Congratulations to CSB researcher Yi Ren on her promotion to Associate Professor of Biochemistry! 🥂
Reposted by Vanderbilt Center for Structural Biology
📚 Did you know? Vanderbilt-affiliated researchers have access to thousands of academic journal articles through the Annette and Irwin Eskind Biomedical Library! Several tools are offered that can be helpful when accessing library resources on the open web. 👉 medschool.vanderbilt.edu/basic-scienc...
Using the Eskind Biomedical Library to access thousands of academic journals
As a researcher affiliated with Vanderbilt University, you should never pay for a scholarly journal article. Vanderbilt’s system of libraries offers several tools that can be helpful when accessing…
medschool.vanderbilt.edu
July 11, 2025 at 3:50 PM
📚 Did you know? Vanderbilt-affiliated researchers have access to thousands of academic journal articles through the Annette and Irwin Eskind Biomedical Library! Several tools are offered that can be helpful when accessing library resources on the open web. 👉 medschool.vanderbilt.edu/basic-scienc...
It's just around the corner! Register now: medschool.vanderbilt.edu/vicb/2025-st...
📣 Save the Date!
Join us Aug 1 at Vanderbilt for the 2025 VICB Student Symposium featuring keynote Dr. Martin Burke (UIUC):
“Imagine a World Where Anyone Can Make Molecules.”
Register ➡️https://medschool.vanderbilt.edu/vicb/2025-student-research-symposium/
Join us Aug 1 at Vanderbilt for the 2025 VICB Student Symposium featuring keynote Dr. Martin Burke (UIUC):
“Imagine a World Where Anyone Can Make Molecules.”
Register ➡️https://medschool.vanderbilt.edu/vicb/2025-student-research-symposium/
July 14, 2025 at 3:13 PM
It's just around the corner! Register now: medschool.vanderbilt.edu/vicb/2025-st...
Reposted by Vanderbilt Center for Structural Biology
Deadline extended! Submit your images to the Second Annual CISR Life is Beautiful Image Contest! New deadline is July 18. Open to anyone with CISR-acquired images. More details here. medschool.vanderbilt.edu/basic-scienc...
July 9, 2025 at 6:28 PM
Deadline extended! Submit your images to the Second Annual CISR Life is Beautiful Image Contest! New deadline is July 18. Open to anyone with CISR-acquired images. More details here. medschool.vanderbilt.edu/basic-scienc...
Reposted by Vanderbilt Center for Structural Biology
🌟 Meet Sheila Elder, an administrative officer for the WCNDD whose passion and dedication make research and operations run smoothly behind the scenes. A fun fact about her? "It has been scientifically proven that I make the best banana pudding in the world." medschool.vanderbilt.edu/basic-scienc...
School of Medicine Basic Sciences Staff Spotlight: Sheila Elder
Meet Sheila Elder, an administrative officer in the Vanderbilt University School of Medicine Basic Sciences who provides financial and administrative leadership for the Warren Center for Neuroscien…
medschool.vanderbilt.edu
July 10, 2025 at 6:30 PM
🌟 Meet Sheila Elder, an administrative officer for the WCNDD whose passion and dedication make research and operations run smoothly behind the scenes. A fun fact about her? "It has been scientifically proven that I make the best banana pudding in the world." medschool.vanderbilt.edu/basic-scienc...
New work from Yang Lab, Link Lab and Yi-Lei Zhao takes a first step toward structural prediction of RiPPs: lasso peptide.
nature.com/articles/s41...
Access the tool here: lassopred.accre.vanderbilt.edu
@vanderbiltvicb.bsky.social
nature.com/articles/s41...
Access the tool here: lassopred.accre.vanderbilt.edu
@vanderbiltvicb.bsky.social
LassoPred: a tool to predict the 3D structure of lasso peptides - Nature Communications
Ouyang et al. present LassoPred, a computational tool to accurately predicts the 3D structure of lasso peptides and offers an accessible online prediction tool to the scientific community.
nature.com
July 7, 2025 at 3:19 PM
New work from Yang Lab, Link Lab and Yi-Lei Zhao takes a first step toward structural prediction of RiPPs: lasso peptide.
nature.com/articles/s41...
Access the tool here: lassopred.accre.vanderbilt.edu
@vanderbiltvicb.bsky.social
nature.com/articles/s41...
Access the tool here: lassopred.accre.vanderbilt.edu
@vanderbiltvicb.bsky.social
New findings from the @chazinwalter.bsky.social lab & collaborators suggest that combining 5hmC with olaparib can restore the sensitivity of chemoresistant BRCA1/2-deficient cells. 🎉Congrats to 1st author Suhas Kharat!
@vubasicsciences.bsky.social
doi.org/10.1016/j.jb...
@vubasicsciences.bsky.social
doi.org/10.1016/j.jb...
June 23, 2025 at 12:21 PM
New findings from the @chazinwalter.bsky.social lab & collaborators suggest that combining 5hmC with olaparib can restore the sensitivity of chemoresistant BRCA1/2-deficient cells. 🎉Congrats to 1st author Suhas Kharat!
@vubasicsciences.bsky.social
doi.org/10.1016/j.jb...
@vubasicsciences.bsky.social
doi.org/10.1016/j.jb...
Reposted by Vanderbilt Center for Structural Biology
🌟 A big congratulations to the BRET ASPIRE team including Ashley Brady, Mary Gray Lindstrom, Angela Zito and Kathy Gould for being a recipient of the Excellence in Corporate Collaboration Awards! This recognition is for their leadership of ASPIRE on the Road. news.vanderbilt.edu/2025/06/11/e...
Excellence in corporate collaboration event recognizes staff achievements in advancing corporate partnerships
The second annual Excellence in Corporate Collaboration Luncheon on May 22 brought together members of the Vanderbilt community at Alumni Hall to celebrate a shared commitment to partnership and…
news.vanderbilt.edu
June 20, 2025 at 3:40 PM
🌟 A big congratulations to the BRET ASPIRE team including Ashley Brady, Mary Gray Lindstrom, Angela Zito and Kathy Gould for being a recipient of the Excellence in Corporate Collaboration Awards! This recognition is for their leadership of ASPIRE on the Road. news.vanderbilt.edu/2025/06/11/e...