Wildtype One
@wildtypeone.bsky.social
🧫 Join 600+ elite researchers getting weekly lab hacks with our newsletter (it’s free) 👉 wildtypeone.substack.com/about
Yes, you can use AI for academic writing—as long as you follow the rules
Here is how to ethically use AI in academic writing:
(key takeaways—a thread 👇)
Here is how to ethically use AI in academic writing:
(key takeaways—a thread 👇)
November 26, 2025 at 8:48 AM
Yes, you can use AI for academic writing—as long as you follow the rules
Here is how to ethically use AI in academic writing:
(key takeaways—a thread 👇)
Here is how to ethically use AI in academic writing:
(key takeaways—a thread 👇)
4 Western blot "non-specific" bands you're cropping out...
that are actually valuable signal!
(a thread)
that are actually valuable signal!
(a thread)
November 25, 2025 at 12:57 PM
4 Western blot "non-specific" bands you're cropping out...
that are actually valuable signal!
(a thread)
that are actually valuable signal!
(a thread)
Researchers,
Retractions can come from innocent (& avoidable) mistakes
Part 1 of this series was real-life examples
Part 2 was honest mistakes that count as misconduct
Part 3 (today): Your simple checklist to avoid misconduct issues
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
Retractions can come from innocent (& avoidable) mistakes
Part 1 of this series was real-life examples
Part 2 was honest mistakes that count as misconduct
Part 3 (today): Your simple checklist to avoid misconduct issues
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
Unintentional fraud: Pre-submission checklist
“If you didn’t write it down, you didn’t do it” — Common laboratory maxim Dear Elite Researcher, Retractions can come from innocent mistakes How do you avoid getting flagged for misconduct? And how do...
www.linkedin.com
November 24, 2025 at 8:24 AM
Researchers,
Retractions can come from innocent (& avoidable) mistakes
Part 1 of this series was real-life examples
Part 2 was honest mistakes that count as misconduct
Part 3 (today): Your simple checklist to avoid misconduct issues
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
Retractions can come from innocent (& avoidable) mistakes
Part 1 of this series was real-life examples
Part 2 was honest mistakes that count as misconduct
Part 3 (today): Your simple checklist to avoid misconduct issues
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
4 microscopy “artifacts” you're throwing away
...that are actually valuable signal!
(a thread)
...that are actually valuable signal!
(a thread)
November 23, 2025 at 11:56 AM
4 microscopy “artifacts” you're throwing away
...that are actually valuable signal!
(a thread)
...that are actually valuable signal!
(a thread)
How can you choose the best fluorescent dye combinations in seconds?
We found a useful online tool that will help you:
(a thread)
We found a useful online tool that will help you:
(a thread)
November 22, 2025 at 6:39 PM
How can you choose the best fluorescent dye combinations in seconds?
We found a useful online tool that will help you:
(a thread)
We found a useful online tool that will help you:
(a thread)
“Where’s the damn question?!”
If Richard Feynman...
(yes, the great physicist)
...were your PI
(yes, in a biology lab)
He'd definitely go over your notebook:
(see thread)
If Richard Feynman...
(yes, the great physicist)
...were your PI
(yes, in a biology lab)
He'd definitely go over your notebook:
(see thread)
November 19, 2025 at 6:52 PM
“Where’s the damn question?!”
If Richard Feynman...
(yes, the great physicist)
...were your PI
(yes, in a biology lab)
He'd definitely go over your notebook:
(see thread)
If Richard Feynman...
(yes, the great physicist)
...were your PI
(yes, in a biology lab)
He'd definitely go over your notebook:
(see thread)
Flow cytometry 🔬 and urinals 🚽 have something in common...
Below is a veteran flow cytometry concept
…that beginners don't know
(a thread)
Below is a veteran flow cytometry concept
…that beginners don't know
(a thread)
November 18, 2025 at 11:23 AM
Flow cytometry 🔬 and urinals 🚽 have something in common...
Below is a veteran flow cytometry concept
…that beginners don't know
(a thread)
Below is a veteran flow cytometry concept
…that beginners don't know
(a thread)
Researchers 🥼,
Retractions can come from innocent mistakes
Luckily, they're avoidable
We created a series
Part 1 was real-life examples
Today is Part 2:
Honest mistakes that count as misconduct
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 3 ⌛)
Retractions can come from innocent mistakes
Luckily, they're avoidable
We created a series
Part 1 was real-life examples
Today is Part 2:
Honest mistakes that count as misconduct
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 3 ⌛)
11 honest lab mistakes that count as fraud
“Integrity is doing the right thing, even when no one is watching.” — C.
www.linkedin.com
November 17, 2025 at 11:11 AM
Researchers 🥼,
Retractions can come from innocent mistakes
Luckily, they're avoidable
We created a series
Part 1 was real-life examples
Today is Part 2:
Honest mistakes that count as misconduct
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 3 ⌛)
Retractions can come from innocent mistakes
Luckily, they're avoidable
We created a series
Part 1 was real-life examples
Today is Part 2:
Honest mistakes that count as misconduct
Read today's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 3 ⌛)
AI taking jobs ❌
AI changing lab standards ✅
Not all lab techniques will make it to 2026
Here are the techniques that will lose their "standard" status by 2026 (see reply 👇)
AI changing lab standards ✅
Not all lab techniques will make it to 2026
Here are the techniques that will lose their "standard" status by 2026 (see reply 👇)
November 16, 2025 at 4:12 PM
AI taking jobs ❌
AI changing lab standards ✅
Not all lab techniques will make it to 2026
Here are the techniques that will lose their "standard" status by 2026 (see reply 👇)
AI changing lab standards ✅
Not all lab techniques will make it to 2026
Here are the techniques that will lose their "standard" status by 2026 (see reply 👇)
Researchers,
What to do when your licence expires?
How do you:
... avoid work interruption?
... save cost?
... choose the best software?
(a thread)
What to do when your licence expires?
How do you:
... avoid work interruption?
... save cost?
... choose the best software?
(a thread)
November 15, 2025 at 10:51 AM
Researchers,
What to do when your licence expires?
How do you:
... avoid work interruption?
... save cost?
... choose the best software?
(a thread)
What to do when your licence expires?
How do you:
... avoid work interruption?
... save cost?
... choose the best software?
(a thread)
Reminder to researchers doing Western blot:
Bacteria and mold can contaminate your TBST too
And this ruins your Western blots
The worst part?
(thread)
Bacteria and mold can contaminate your TBST too
And this ruins your Western blots
The worst part?
(thread)
November 13, 2025 at 11:31 AM
Reminder to researchers doing Western blot:
Bacteria and mold can contaminate your TBST too
And this ruins your Western blots
The worst part?
(thread)
Bacteria and mold can contaminate your TBST too
And this ruins your Western blots
The worst part?
(thread)
The most iconic moments in the history of biology (a thread)
November 12, 2025 at 7:26 AM
The most iconic moments in the history of biology (a thread)
Researchers,
Misconduct can be unintentional
It could be a mistake on the bench (or in the office)
I.e., it's avoidable
We created a series around this topic
This is Part 1
Read this week's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 2 ⌛)
Misconduct can be unintentional
It could be a mistake on the bench (or in the office)
I.e., it's avoidable
We created a series around this topic
This is Part 1
Read this week's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 2 ⌛)
How to avoid "unintentional fraud"
“The important thing is to never stop questioning.” — Albert Einstein Dear Elite Researcher, Your paper can get retracted because of data concerns But you’ve never meant to fake any data It was uninte...
www.linkedin.com
November 11, 2025 at 6:38 PM
Researchers,
Misconduct can be unintentional
It could be a mistake on the bench (or in the office)
I.e., it's avoidable
We created a series around this topic
This is Part 1
Read this week's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 2 ⌛)
Misconduct can be unintentional
It could be a mistake on the bench (or in the office)
I.e., it's avoidable
We created a series around this topic
This is Part 1
Read this week's Elite Researcher's Weekly, in 3 minutes or less 👇
(...and stay tuned for Part 2 ⌛)
Choosing the wrong test can cost you statistical power.
Here's how to decide:
(a thread)
Here's how to decide:
(a thread)
November 10, 2025 at 7:17 AM
Choosing the wrong test can cost you statistical power.
Here's how to decide:
(a thread)
Here's how to decide:
(a thread)
Reposted by Wildtype One
Once again, I beg you to understand that SINGLE-CHANNEL FLUORESCENCE MICROSCOPY IMAGES DON'T HAVE A COLOR!
November 9, 2025 at 3:13 PM
Once again, I beg you to understand that SINGLE-CHANNEL FLUORESCENCE MICROSCOPY IMAGES DON'T HAVE A COLOR!
Not all lab techniques will make it to 2026
Labs evolve fast
Habits don’t
Many “standard” methods are no longer necessary
Better, more powerful options are replacing them
Here are some examples 👇
(a thread)
Labs evolve fast
Habits don’t
Many “standard” methods are no longer necessary
Better, more powerful options are replacing them
Here are some examples 👇
(a thread)
November 9, 2025 at 4:48 PM
Not all lab techniques will make it to 2026
Labs evolve fast
Habits don’t
Many “standard” methods are no longer necessary
Better, more powerful options are replacing them
Here are some examples 👇
(a thread)
Labs evolve fast
Habits don’t
Many “standard” methods are no longer necessary
Better, more powerful options are replacing them
Here are some examples 👇
(a thread)
"What should I do after the PhD?"
"Can I find a job?"
"Will I get the position I want?"
…
Here's some good news:
"Can I find a job?"
"Will I get the position I want?"
…
Here's some good news:
October 30, 2025 at 6:46 AM
"What should I do after the PhD?"
"Can I find a job?"
"Will I get the position I want?"
…
Here's some good news:
"Can I find a job?"
"Will I get the position I want?"
…
Here's some good news:
One of the most legendary papers in molecular biology was written by a postdoc...
He didn’t even mean to create it.
🧬 Quick backstory—1970
Ulrich Laemmli was a young postdoc at the MRC-LMB in Cambridge.
(a thread)
He didn’t even mean to create it.
🧬 Quick backstory—1970
Ulrich Laemmli was a young postdoc at the MRC-LMB in Cambridge.
(a thread)
October 26, 2025 at 6:25 PM
One of the most legendary papers in molecular biology was written by a postdoc...
He didn’t even mean to create it.
🧬 Quick backstory—1970
Ulrich Laemmli was a young postdoc at the MRC-LMB in Cambridge.
(a thread)
He didn’t even mean to create it.
🧬 Quick backstory—1970
Ulrich Laemmli was a young postdoc at the MRC-LMB in Cambridge.
(a thread)
Many young researchers believe the myth that isotype control is the best negative control.
Here's the truth 👇
Here's the truth 👇
October 22, 2025 at 7:01 AM
Many young researchers believe the myth that isotype control is the best negative control.
Here's the truth 👇
Here's the truth 👇
What do you think matters most when sending your draft to Nature?
Surprise: It's not your track record!
Heathcliff Dorado García (PhD and Nature Portfolio Editor) shared a few nuggets on publishing in prestigious journals ✍
Read today's Elite Researcher Weekly for more 👇
Surprise: It's not your track record!
Heathcliff Dorado García (PhD and Nature Portfolio Editor) shared a few nuggets on publishing in prestigious journals ✍
Read today's Elite Researcher Weekly for more 👇
How to publish in Nature (3-minute editor's advice)
“It doesn’t matter how beautiful your theory is… if it doesn’t agree with experiment, it’s wrong.” — Richard Feynman Dear Elite Researcher, We all would love to publish in the world’s highest-impact j...
www.linkedin.com
October 14, 2025 at 5:01 AM
What do you think matters most when sending your draft to Nature?
Surprise: It's not your track record!
Heathcliff Dorado García (PhD and Nature Portfolio Editor) shared a few nuggets on publishing in prestigious journals ✍
Read today's Elite Researcher Weekly for more 👇
Surprise: It's not your track record!
Heathcliff Dorado García (PhD and Nature Portfolio Editor) shared a few nuggets on publishing in prestigious journals ✍
Read today's Elite Researcher Weekly for more 👇
Reposted by Wildtype One
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
October 2, 2025 at 5:11 PM
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
Here's a very bad flow cytometry advice: “autofluorescence needs to be minimized”
Analogy: Imagine you're watching TV and you have static...
(a thread)
Analogy: Imagine you're watching TV and you have static...
(a thread)
October 3, 2025 at 5:20 AM
Here's a very bad flow cytometry advice: “autofluorescence needs to be minimized”
Analogy: Imagine you're watching TV and you have static...
(a thread)
Analogy: Imagine you're watching TV and you have static...
(a thread)
Albert Einstein would've hated Western blots...
(a thread)
(a thread)
September 28, 2025 at 9:14 AM
Albert Einstein would've hated Western blots...
(a thread)
(a thread)
Reposted by Wildtype One
Historians of science agree that the postdoc was invented just after the Western blot, as even the inventor wouldn't want to run one
September 23, 2025 at 2:30 PM
Historians of science agree that the postdoc was invented just after the Western blot, as even the inventor wouldn't want to run one