Ryan Radecki MD MS
@www.evidencetriage.com
FACEP FACEM ABPM-CI. HealthNZ AI & Christchurch EM. Annals of EM Podcast & Journal Club. Columnist ACEPNow. Speaker, writer, dad. Stanford '00. evidencetriage.com 🇺🇸 in 🇳🇿
The new reality: if you have a information aggregation/interpretation problem that previously required a team of engineers and data scientists, there's an awfully good chance Claude Code or a tool like it can address it given functional requirements.
#medsky
medium.com/data-science...
#medsky
medium.com/data-science...
I Gave Claude Code 9.5 Years of Health Data to Help Manage my Thyroid Disease
A case study in personal machine learning, agentic coding, and why the future of health management might be personalized ML
medium.com
January 21, 2026 at 3:20 AM
The new reality: if you have a information aggregation/interpretation problem that previously required a team of engineers and data scientists, there's an awfully good chance Claude Code or a tool like it can address it given functional requirements.
#medsky
medium.com/data-science...
#medsky
medium.com/data-science...
Example #2914 of telling clinicians there's no bacteria to treat, but clinicians continuing the antibiotics.
(in this case, the test is flawed, but I digress)
#medsky
www.evidencetriage.com/p/no-bacteri...
(in this case, the test is flawed, but I digress)
#medsky
www.evidencetriage.com/p/no-bacteri...
No Bacteria? No Antibiotics? No?
Changing practice is harder than providing a test result.
www.evidencetriage.com
January 19, 2026 at 10:23 PM
Example #2914 of telling clinicians there's no bacteria to treat, but clinicians continuing the antibiotics.
(in this case, the test is flawed, but I digress)
#medsky
www.evidencetriage.com/p/no-bacteri...
(in this case, the test is flawed, but I digress)
#medsky
www.evidencetriage.com/p/no-bacteri...
Emoji usage is slowly percolating into clinical documentation – and with some rather quirky choices, if I might say.
#medsky
www.evidencetriage.com/p/emojis-in-...
#medsky
www.evidencetriage.com/p/emojis-in-...
😬 Emojis in Clinical Documentation 😭
No, thank you – but, does Gen Z/Gen Alpha care what I think?
www.evidencetriage.com
January 18, 2026 at 10:59 PM
Emoji usage is slowly percolating into clinical documentation – and with some rather quirky choices, if I might say.
#medsky
www.evidencetriage.com/p/emojis-in-...
#medsky
www.evidencetriage.com/p/emojis-in-...
Reposted by Ryan Radecki MD MS
Amusingly, the cost-effectiveness manuscript produced by Roche assumed the floor for CENTERSTONE would be a reduction in transmission of 5% ... when in actuality, the reduction in symptomatic cases was less than 2%.
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Cost-Effectiveness of Baloxavir Marboxil Versus Oseltamivir or no Treatment for the Management of Influenza in the United States
This study sought to evaluate the cost-effectiveness of baloxavir marboxil compared with oseltamivir or no antiviral treatment from a US payer perspective using data from a real-world US administrativ...
pmc.ncbi.nlm.nih.gov
April 24, 2025 at 8:05 PM
Amusingly, the cost-effectiveness manuscript produced by Roche assumed the floor for CENTERSTONE would be a reduction in transmission of 5% ... when in actuality, the reduction in symptomatic cases was less than 2%.
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted by Ryan Radecki MD MS
Most people don't need an antiviral to treat influenza, the least of which being Xofluza – unless you're bored with just causing antibiotic resistance and want to start working on some new influenza mutations.
#medsky
www.evidencetriage.com/p/another-ba...
#medsky
www.evidencetriage.com/p/another-ba...
Another Baloxavir Advertorial In NEJM
Does anyone seriously make treatment decisions off this pharma junk?
www.evidencetriage.com
April 24, 2025 at 8:02 PM
Most people don't need an antiviral to treat influenza, the least of which being Xofluza – unless you're bored with just causing antibiotic resistance and want to start working on some new influenza mutations.
#medsky
www.evidencetriage.com/p/another-ba...
#medsky
www.evidencetriage.com/p/another-ba...
Important Science — future IgNobel award?
www.pbs.org/wgbh/nova/ar...
www.pbs.org/wgbh/nova/ar...
How Does Microwaving Grapes Create Plasma? | NOVA | PBS
No kitchen appliances were harmed in the writing of this article.
www.pbs.org
January 9, 2026 at 8:50 PM
Important Science — future IgNobel award?
www.pbs.org/wgbh/nova/ar...
www.pbs.org/wgbh/nova/ar...
Sweet merciful Jessica, look at all those false-positive D-dimers.
So, yes, please age-adjust your D-dimer for DVT, as well as PE. It doesn't make a big difference, but any improvement is welcome ...
#medsky
www.evidencetriage.com/p/adjust-again
So, yes, please age-adjust your D-dimer for DVT, as well as PE. It doesn't make a big difference, but any improvement is welcome ...
#medsky
www.evidencetriage.com/p/adjust-again
ADJUST, Again
VTE is VTE, whether PE or DVT!
www.evidencetriage.com
January 9, 2026 at 7:28 PM
Sweet merciful Jessica, look at all those false-positive D-dimers.
So, yes, please age-adjust your D-dimer for DVT, as well as PE. It doesn't make a big difference, but any improvement is welcome ...
#medsky
www.evidencetriage.com/p/adjust-again
So, yes, please age-adjust your D-dimer for DVT, as well as PE. It doesn't make a big difference, but any improvement is welcome ...
#medsky
www.evidencetriage.com/p/adjust-again
FFS.
Don't waste your time or money trying to chase this junk down ....
www.bloomberg.com/news/article...
Don't waste your time or money trying to chase this junk down ....
www.bloomberg.com/news/article...
Flu Patients Struggle to Find Tamiflu as Virus Surges Across US
The antiviral treatment Tamiflu is in short supply in parts of the US, as patients and pharmacists battle one of the worst flu seasons in decades.
www.bloomberg.com
January 9, 2026 at 6:53 PM
FFS.
Don't waste your time or money trying to chase this junk down ....
www.bloomberg.com/news/article...
Don't waste your time or money trying to chase this junk down ....
www.bloomberg.com/news/article...
Reposted by Ryan Radecki MD MS
So when authorities say “she tried to run over an officer,” that is not a neutral description. It is a claim of intent that can be used to justify lethal force after the fact.
When the state kills first and invents the threat afterward, it is not policing, it is death squad behavior. /end
When the state kills first and invents the threat afterward, it is not policing, it is death squad behavior. /end
January 8, 2026 at 9:13 PM
So when authorities say “she tried to run over an officer,” that is not a neutral description. It is a claim of intent that can be used to justify lethal force after the fact.
When the state kills first and invents the threat afterward, it is not policing, it is death squad behavior. /end
When the state kills first and invents the threat afterward, it is not policing, it is death squad behavior. /end
"Entropy reduction" as a path to diagnostic certainty – a fun thought experiment trying to quantify which information in the emergency department contributes most towards clarifying diagnoses.
#medsky #MLsky
www.evidencetriage.com/p/what-reduc...
#medsky #MLsky
www.evidencetriage.com/p/what-reduc...
What Reduces Diagnostic Uncertainty in the Emergency Department?
The donut (or ultrasound lasso) of truth.
www.evidencetriage.com
January 8, 2026 at 11:45 PM
"Entropy reduction" as a path to diagnostic certainty – a fun thought experiment trying to quantify which information in the emergency department contributes most towards clarifying diagnoses.
#medsky #MLsky
www.evidencetriage.com/p/what-reduc...
#medsky #MLsky
www.evidencetriage.com/p/what-reduc...
AI agents are everywhere – but what are the "hidden" biases underlying their actions? Or, how could health system or patient-oriented values be in embedded in an agent?
#medsky #MLsky
www.evidencetriage.com/p/what-kind-...
#medsky #MLsky
www.evidencetriage.com/p/what-kind-...
What Kind of Doctor Is Your AI?
Chaotic good, neutral, or evil?
www.evidencetriage.com
January 4, 2026 at 7:52 PM
AI agents are everywhere – but what are the "hidden" biases underlying their actions? Or, how could health system or patient-oriented values be in embedded in an agent?
#medsky #MLsky
www.evidencetriage.com/p/what-kind-...
#medsky #MLsky
www.evidencetriage.com/p/what-kind-...
New year, new you?
Come revive your love of emergency medicine in New Zealand.
Easiest search: type "FACEM" into Keywords, and you'll see all the consultant-level posts. Everything from surfing and sun in Gisborne to ... something different in Wellington!
jobs.tewhatuora.govt.nz/jobtools/jnc...
Come revive your love of emergency medicine in New Zealand.
Easiest search: type "FACEM" into Keywords, and you'll see all the consultant-level posts. Everything from surfing and sun in Gisborne to ... something different in Wellington!
jobs.tewhatuora.govt.nz/jobtools/jnc...
Health New Zealand / Māori Health Authority
Health New Zealand / Māori Health Authority
jobs.tewhatuora.govt.nz
January 2, 2026 at 7:07 AM
New year, new you?
Come revive your love of emergency medicine in New Zealand.
Easiest search: type "FACEM" into Keywords, and you'll see all the consultant-level posts. Everything from surfing and sun in Gisborne to ... something different in Wellington!
jobs.tewhatuora.govt.nz/jobtools/jnc...
Come revive your love of emergency medicine in New Zealand.
Easiest search: type "FACEM" into Keywords, and you'll see all the consultant-level posts. Everything from surfing and sun in Gisborne to ... something different in Wellington!
jobs.tewhatuora.govt.nz/jobtools/jnc...
No, "sepsis" is not any ED patient a fever – it's a complex, impaired host response to infection.
Someday, that impaired response will be recognized as a heterogeneous tapestry of induced dysfunction, each with its own tailored treatment.
#medsky
www.evidencetriage.com/p/reversing-...
Someday, that impaired response will be recognized as a heterogeneous tapestry of induced dysfunction, each with its own tailored treatment.
#medsky
www.evidencetriage.com/p/reversing-...
Reversing "Immune Paralysis" in Sepsis
A glimpse of the far future.
www.evidencetriage.com
January 1, 2026 at 9:15 PM
No, "sepsis" is not any ED patient a fever – it's a complex, impaired host response to infection.
Someday, that impaired response will be recognized as a heterogeneous tapestry of induced dysfunction, each with its own tailored treatment.
#medsky
www.evidencetriage.com/p/reversing-...
Someday, that impaired response will be recognized as a heterogeneous tapestry of induced dysfunction, each with its own tailored treatment.
#medsky
www.evidencetriage.com/p/reversing-...
Almost no low-risk children will have SBI, and an even tinier fraction will be missed meningitis – but at what point is "minimal risk" acceptable versus "zero risk"?
#medsky
www.evidencetriage.com/p/can-we-yet...
#medsky
www.evidencetriage.com/p/can-we-yet...
Can We Yet Escape The Neonatal Lumbar Puncture?
... maybe?
www.evidencetriage.com
December 30, 2025 at 11:55 PM
Almost no low-risk children will have SBI, and an even tinier fraction will be missed meningitis – but at what point is "minimal risk" acceptable versus "zero risk"?
#medsky
www.evidencetriage.com/p/can-we-yet...
#medsky
www.evidencetriage.com/p/can-we-yet...
Merry Christmas from my cats. 😐
December 25, 2025 at 9:35 AM
Merry Christmas from my cats. 😐
It’s a bird!
No, it’s a plane!
No, it’s
No, it’s a plane!
No, it’s
December 22, 2025 at 9:40 PM
It’s a bird!
No, it’s a plane!
No, it’s
No, it’s a plane!
No, it’s
Reposted by Ryan Radecki MD MS
RFK Jr. should have paid more attention to the comics in 1968.
December 20, 2025 at 12:43 AM
RFK Jr. should have paid more attention to the comics in 1968.
Which physicians are the highest-earning cogs in the private equity machine?
Unsurprisingly, gastroenterology, cardiology, and ophthalmology – especially those who own their own imaging, endoscopy, and surgical centers.
This is all obviously good for patients. Ha!
focusbankers.com/physician-pr...
Unsurprisingly, gastroenterology, cardiology, and ophthalmology – especially those who own their own imaging, endoscopy, and surgical centers.
This is all obviously good for patients. Ha!
focusbankers.com/physician-pr...
Physician Practice M&A Multiples: 2025 Data
Current physician practice M&A multiples for 2025 by specialty with EBITDA and enterprise value ranges for platform and add-on transactions.
focusbankers.com
December 19, 2025 at 5:49 PM
Which physicians are the highest-earning cogs in the private equity machine?
Unsurprisingly, gastroenterology, cardiology, and ophthalmology – especially those who own their own imaging, endoscopy, and surgical centers.
This is all obviously good for patients. Ha!
focusbankers.com/physician-pr...
Unsurprisingly, gastroenterology, cardiology, and ophthalmology – especially those who own their own imaging, endoscopy, and surgical centers.
This is all obviously good for patients. Ha!
focusbankers.com/physician-pr...
More of the same biases towards blanket treatment with IVT of any stroke that smells like "disability" (definition of disability not available).
#medsky
www.evidencetriage.com/p/minor-upda...
#medsky
www.evidencetriage.com/p/minor-upda...
Minor Updates For Minor Stroke
Minor stroke is all in the eye of the beholder.
www.evidencetriage.com
December 19, 2025 at 5:45 PM
More of the same biases towards blanket treatment with IVT of any stroke that smells like "disability" (definition of disability not available).
#medsky
www.evidencetriage.com/p/minor-upda...
#medsky
www.evidencetriage.com/p/minor-upda...
The state of AI use in primary care in the UK: a lotta scribes and a lot of additional non-clinical needs.
#medsky
www.evidencetriage.com/p/how-are-gp...
#medsky
www.evidencetriage.com/p/how-are-gp...
How Are GPs Using AI?
And how do they wish they could?
www.evidencetriage.com
December 17, 2025 at 7:34 PM
The state of AI use in primary care in the UK: a lotta scribes and a lot of additional non-clinical needs.
#medsky
www.evidencetriage.com/p/how-are-gp...
#medsky
www.evidencetriage.com/p/how-are-gp...
What's your strategy for using LLMs to augment your clinical decision-making?
(now, if we only had objective data regarding which was "best")
#medsky #MLsky
www.evidencetriage.com/p/are-you-a-...
(now, if we only had objective data regarding which was "best")
#medsky #MLsky
www.evidencetriage.com/p/are-you-a-...
Are You A "Copy-Paster" Or A "Summarizer"?
Or something else entirely?
www.evidencetriage.com
December 16, 2025 at 5:54 PM
What's your strategy for using LLMs to augment your clinical decision-making?
(now, if we only had objective data regarding which was "best")
#medsky #MLsky
www.evidencetriage.com/p/are-you-a-...
(now, if we only had objective data regarding which was "best")
#medsky #MLsky
www.evidencetriage.com/p/are-you-a-...
I'm running the Chicago Marathon next year in support of Team ALS –
– my choice of charity and my connection is personal, and I encourage everyone simply to give what they can to a charity meaningful to them.
That said, donations are matched in Dec –
secure.alsunitedchicago.org/site/TR/Endu...
– my choice of charity and my connection is personal, and I encourage everyone simply to give what they can to a charity meaningful to them.
That said, donations are matched in Dec –
secure.alsunitedchicago.org/site/TR/Endu...
2026 Team ALS - Bank of America Chicago Marathon: Dr. Ryan Radecki - ALS United Greater Chicago
secure.alsunitedchicago.org
December 16, 2025 at 5:24 PM
I'm running the Chicago Marathon next year in support of Team ALS –
– my choice of charity and my connection is personal, and I encourage everyone simply to give what they can to a charity meaningful to them.
That said, donations are matched in Dec –
secure.alsunitedchicago.org/site/TR/Endu...
– my choice of charity and my connection is personal, and I encourage everyone simply to give what they can to a charity meaningful to them.
That said, donations are matched in Dec –
secure.alsunitedchicago.org/site/TR/Endu...
“Within 48 hours of the Bondi shooting, federal and state leaders in Australia pledged to further tighten the country’s gun laws, already some of the most restrictive in the world … They noted that they were a lot more concrete than the ‘thoughts and prayers’ so often offered by American officials.”
Dean @meganranney.bsky.social joined CNN the day after mass shootings at Brown University and Bondi Beach to discuss the long-term mental and physical health impact of these events.
Dean Ranney is an emergency physician and firearm injury prevention researcher and spent 20 years at Brown.
Dean Ranney is an emergency physician and firearm injury prevention researcher and spent 20 years at Brown.
December 16, 2025 at 3:39 PM
“Within 48 hours of the Bondi shooting, federal and state leaders in Australia pledged to further tighten the country’s gun laws, already some of the most restrictive in the world … They noted that they were a lot more concrete than the ‘thoughts and prayers’ so often offered by American officials.”