Rolando Masís-Obando
@xrmasiso.bsky.social
140 followers 240 following 16 posts
now: neuro postdoc with Janice Chen & Chris Honey @ Johns Hopkins. before: neuro phd student with Ken Norman @ Princeton & Chris Baldassano @ Columbia | dspan
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xrmasiso.bsky.social
🔔𝐍𝐄𝐖 𝐏𝐑𝐄𝐏𝐑𝐈𝐍𝐓 𝐀𝐋𝐄𝐑𝐓🔔 Beyond excited to present our new work showcasing 𝐡𝐨𝐰 𝐰𝐞 𝐜𝐚𝐧 𝐩𝐫𝐞𝐝𝐢𝐜𝐭 𝐡𝐨𝐰 𝐰𝐞𝐥𝐥 𝐲𝐨𝐮 𝐰𝐢𝐥𝐥 𝐫𝐞𝐢𝐧𝐬𝐭𝐚𝐭𝐞 𝐚 𝐧𝐞𝐰 𝐦𝐞𝐦𝐨𝐫𝐲 𝐛𝐞𝐟𝐨𝐫𝐞 𝐭𝐡𝐚𝐭 𝐦𝐞𝐦𝐨𝐫𝐲 𝐢𝐬 𝐟𝐨𝐫𝐦𝐞𝐝! Wait what? Exciting collab w/ @ptoncompmemlab.bsky.social & @chrisbaldassano.bsky.social Link: www.biorxiv.org/content/10.1... (1/11)
xrmasiso.bsky.social
super cool work from @jay_neuro on how music shapes our memories of the movies we watch: folks watched a jim carrey movie & the musical themes reactivated memories from the movie! ||| sounds like i should hire a composer to score my life so i can improve my memory 🎹🎵🎶
jayneuro.bsky.social
Music is an incredibly powerful retrieval cue. What is the neural basis of music-evoked memory reactivation? And how does this reactivation relate to later memory for the retrieved events? In our new study, we used Eternal Sunshine of the Spotless Mind to find out. www.biorxiv.org/content/10.1...
Music-evoked reactivation during continuous perception is associated with enhanced subsequent recall of naturalistic events
Music is a potent cue for recalling personal experiences, yet the neural basis of music-evoked memory remains elusive. We address this question by using the full-length film Eternal Sunshine of the Spotless Mind to examine how repeated musical themes reactivate previously encoded events in cortex and shape next-day recall. Participants in an fMRI study viewed either the original film (with repeated musical themes) or a no-music version. By comparing neural activity patterns between these groups, we found that music-evoked reactivation of neural patterns linked to earlier scenes in the default mode network was associated with improved subsequent recall. This relationship was specific to the music condition and persisted when we controlled for a proxy measure of initial encoding strength (spatial intersubject correlation), suggesting that music-evoked reactivation may play a role in making event memories stick that is distinct from what happens at initial encoding. ### Competing Interest Statement The authors have declared no competing interest. National Institutes of Health, https://ror.org/01cwqze88, F99 NS118740, R01 MH112357
www.biorxiv.org
xrmasiso.bsky.social
#CNS2025 was such a blast! It was a delight to work & present our symposium on how VR can be leveraged in neuro/psych research! Make sure to check out the cool research being done by my fellow speakers @tammyish.bsky.social & @manusmad.bsky.social & Birgit Peña Häufler! Excited for #CNS2026 !
cogneuronews.bsky.social
Finishing strong with the final set of symposia at #CNS2025!
We're in Session 11 on harnessing #VR to study memory and navigation across the lifespan, including as a potential diagnostic tool for Alzheimer's
Reposted by Rolando Masís-Obando
chrisbaldassano.bsky.social
For anyone at #CNS2025 - check out @xrmasiso.bsky.social's talk tomorrow afternoon, showing that we can use fMRI to predict which (VR) locations will be good anchors for creating *future* memories!
www.cogneurosociety.org/talk/?id=5579
Symposium Talk - Cognitive Neuroscience Society
March 29-April 1  |  2025 Submit a Symposium Submit a Poster Latest from Twitter
www.cogneurosociety.org
xrmasiso.bsky.social
#neuroskyence #psychscisky
xrmasiso.bsky.social
This means we were able to 𝐝𝐢𝐚𝐠𝐧𝐨𝐬𝐞 whether a room will serve as an effective memory scaffold 𝐁𝐄𝐅𝐎𝐑𝐄 objects are placed in the room! (10/11)
xrmasiso.bsky.social
In accordance with our predictions, we found that we were able 𝐭𝐨 𝐮𝐬𝐞 𝐞𝐚𝐜𝐡 𝐢𝐧𝐝𝐢𝐯𝐢𝐝𝐮𝐚𝐥 𝐩𝐚𝐫𝐭𝐢𝐜𝐢𝐩𝐚𝐧𝐭’𝐬 𝐫𝐨𝐨𝐦 𝐫𝐞𝐥𝐢𝐚𝐛𝐢𝐥𝐢𝐭𝐲 (measured before they saw the newly placed objects) 𝐭𝐨 𝐩𝐫𝐞𝐝𝐢𝐜𝐭 𝐭𝐡𝐞 𝐝𝐞𝐠𝐫𝐞𝐞 𝐨𝐟 𝐨𝐛𝐣𝐞𝐜𝐭 𝐫𝐞𝐢𝐧𝐬𝐭𝐚𝐭𝐞𝐦𝐞𝐧𝐭 𝐝𝐮𝐫𝐢𝐧𝐠 𝐯𝐞𝐫𝐛𝐚𝐥 𝐫𝐞𝐜𝐚𝐥𝐥! (9/11)
xrmasiso.bsky.social
…then, we placed an object randomly in each of the rooms and had participants go back into VR to learn the room-object associations. Finally, we scanned their brains again while they verbally recalled the objects and the rooms. (8/11)
xrmasiso.bsky.social
Treating each room video as a ‘localizer’, we quantified the reliability of each room representation by comparing the neural pattern similarity of a room to itself vs other rooms… (7/11)
xrmasiso.bsky.social
To test this, we built a 23-room virtual reality (VR) environment that participants explored with a head-mounted display. Afterwards, we scanned their brains while they watched two sets of videos of the rooms they visited. (6/11)
xrmasiso.bsky.social
…we would predict that when a new experience occurs (such as encountering a yummy banana), he would be better at encoding his experience and consequently, better at retrieving it later. (5/11)
xrmasiso.bsky.social
So, we hypothesized that a 𝐡𝐢𝐠𝐡 𝐪𝐮𝐚𝐥𝐢𝐭𝐲 (𝐫𝐞𝐥𝐢𝐚𝐛𝐥𝐞) 𝐫𝐨𝐨𝐦 𝐫𝐞𝐩𝐫𝐞𝐬𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 (one that is stable and distinct) 𝐰𝐨𝐮𝐥𝐝 𝐥𝐞𝐚𝐝 𝐭𝐨 𝐢𝐦𝐩𝐫𝐨𝐯𝐞𝐝 𝐦𝐞𝐦𝐨𝐫𝐲 𝐟𝐨𝐫 𝐨𝐛𝐣𝐞𝐜𝐭𝐬 𝐬𝐮𝐛𝐬𝐞𝐪𝐮𝐞𝐧𝐭𝐥𝐲 𝐩𝐥𝐚𝐜𝐞𝐝 𝐢𝐧 𝐭𝐡𝐞 𝐫𝐨𝐨𝐦. For example, if the typing minion has a reliable room representation… (4/11)
xrmasiso.bsky.social
However, it’s important that the 𝐫𝐞𝐩𝐫𝐞𝐬𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐚 𝐥𝐨𝐜𝐚𝐭𝐢𝐨𝐧 𝐢𝐬 𝐫𝐞𝐥𝐢𝐚𝐛𝐥𝐞! In other words, it 𝐧𝐞𝐞𝐝𝐬 𝐭𝐨 𝐛𝐞 𝐬𝐭𝐚𝐛𝐥𝐞 (so that we can retrieve the details consistently), 𝐛𝐮𝐭 𝐚𝐥𝐬𝐨 𝐝𝐢𝐬𝐭𝐢𝐧𝐜𝐭 (so that the memories across different locations don’t interfere!) (3/11)
xrmasiso.bsky.social
You know when you spontaneously remember old memories when you enter your childhood home? Our lived experiences are often tied to the location in which they occur! 𝐎𝐮𝐫 𝐛𝐫𝐚𝐢𝐧 𝐜𝐚𝐧 𝐮𝐬𝐞 𝐭𝐡𝐞 𝐫𝐞𝐩𝐫𝐞𝐬𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐚 𝐥𝐨𝐜𝐚𝐭𝐢𝐨𝐧 𝐭𝐨 𝐡𝐞𝐥𝐩 𝐠𝐮𝐢𝐝𝐞 𝐨𝐮𝐫 𝐫𝐞𝐜𝐨𝐥𝐥𝐞𝐜𝐭𝐢𝐨𝐧 𝐭𝐨𝐰𝐚𝐫𝐝𝐬 𝐭𝐡𝐞 𝐦𝐞𝐦𝐨𝐫𝐢𝐞𝐬 𝐭𝐡𝐚𝐭 𝐨𝐜𝐜𝐮𝐫𝐫𝐞𝐝 𝐭𝐡𝐞𝐫𝐞. (2/11)
xrmasiso.bsky.social
🔔𝐍𝐄𝐖 𝐏𝐑𝐄𝐏𝐑𝐈𝐍𝐓 𝐀𝐋𝐄𝐑𝐓🔔 Beyond excited to present our new work showcasing 𝐡𝐨𝐰 𝐰𝐞 𝐜𝐚𝐧 𝐩𝐫𝐞𝐝𝐢𝐜𝐭 𝐡𝐨𝐰 𝐰𝐞𝐥𝐥 𝐲𝐨𝐮 𝐰𝐢𝐥𝐥 𝐫𝐞𝐢𝐧𝐬𝐭𝐚𝐭𝐞 𝐚 𝐧𝐞𝐰 𝐦𝐞𝐦𝐨𝐫𝐲 𝐛𝐞𝐟𝐨𝐫𝐞 𝐭𝐡𝐚𝐭 𝐦𝐞𝐦𝐨𝐫𝐲 𝐢𝐬 𝐟𝐨𝐫𝐦𝐞𝐝! Wait what? Exciting collab w/ @ptoncompmemlab.bsky.social & @chrisbaldassano.bsky.social Link: www.biorxiv.org/content/10.1... (1/11)
xrmasiso.bsky.social
I'm also starting to migrate! Thanks for putting this together, Avi!