Wing Yui Ngan
@yuingan.bsky.social
Wing Yui Ngan
Postdoc @phar.cam.ac.uk working with @psalmotoxin.bsky.social and naked mole-rats.
Interested in evolution, genomics, disease mechanisms, RNA, etc.
Postdoc @phar.cam.ac.uk working with @psalmotoxin.bsky.social and naked mole-rats.
Interested in evolution, genomics, disease mechanisms, RNA, etc.
@bramvandijk.bsky.social (and many other)'s new paper covered insights in microbial ecology, evolution and theoretical biology.
Wrapping up a productive week: very glad to have contributed to this review on how spatial structure shapes microbial ecology and evolution, led by @marcelbaecker.bsky.social, @bedutilh.bsky.social, @bramvandijk.bsky.social and many others. doi.org/10.1093/fems...
Spatial structure: shaping the ecology and evolution of microbial communities
Spatial structure naturally emerges in microbial communities, shaping growth, interactions, and evolution, and revealing how microscale processes scale up
doi.org
February 12, 2026 at 1:58 PM
@bramvandijk.bsky.social (and many other)'s new paper covered insights in microbial ecology, evolution and theoretical biology.
Reposted by Wing Yui Ngan
Come & join us: Within @phar.cam.ac.uk, we have a a PhD studentship available for an October 2026 start in collaboration with @MaxionTx as part of the BioSCaPe programme www.babraham.ac.uk/work-and-stu.... Project details 👉 www.findaphd.com/phds/project...
BioSCaPe PhD programme | Babraham Institute
Bioscience South Cambridge doctoral training Partnership (BioSCaPe) is a transformative PhD programme designed to create the bioscience leaders of tomorrow. Based in the heart of the world-leading Cam...
www.babraham.ac.uk
December 22, 2025 at 5:05 PM
Come & join us: Within @phar.cam.ac.uk, we have a a PhD studentship available for an October 2026 start in collaboration with @MaxionTx as part of the BioSCaPe programme www.babraham.ac.uk/work-and-stu.... Project details 👉 www.findaphd.com/phds/project...
This Wednesday, the naked mole-rat team gathered at Corpus Christi College for a formal dinner.
Thank you @psalmotoxin.bsky.social for the invitation.
Thank you @psalmotoxin.bsky.social for the invitation.
November 14, 2025 at 1:19 PM
This Wednesday, the naked mole-rat team gathered at Corpus Christi College for a formal dinner.
Thank you @psalmotoxin.bsky.social for the invitation.
Thank you @psalmotoxin.bsky.social for the invitation.
Looks interesting.
Currently, SeqHub is optimized for microbial protein and genome analysis. As we expand beyond microbial data, we'd love your feedback to help shape what comes next. I'm deeply grateful to our team at Tatta Bio, and to our collaborators and funders, for making this vision a reality. 🔗 seqhub.org
SeqHub
SeqHub is a platform for exploring, annotating, and sharing biological sequences.
seqhub.org
October 30, 2025 at 2:59 PM
Looks interesting.
Reposted by Wing Yui Ngan
A good #PainResearch week for Lanhui Qiu in the lab. After being co-first author on our sphingomyelin paper www.oarsijournal.com/article/S106..., her sole first author paper examining the effects of artemin on mouse vs. naked mole-rat sensory neurons is out 😀 link.springer.com/article/10.1...
a cartoon penguin with the words success penguin behind him
Alt: A cartoon penguin with the words success penguin behind him
media.tenor.com
July 24, 2025 at 12:43 PM
A good #PainResearch week for Lanhui Qiu in the lab. After being co-first author on our sphingomyelin paper www.oarsijournal.com/article/S106..., her sole first author paper examining the effects of artemin on mouse vs. naked mole-rat sensory neurons is out 😀 link.springer.com/article/10.1...
Reposted by Wing Yui Ngan
Our #PainResearch paper showing that sphingomyelin 34:1 (⬆️ in 🧍osteoarthritis synovial fluid) sensitises 🐁 sensory neurons in vitro & causes pain behaviours + knee-innervating neuronal hyperexcitability in 🐁 in vivo is now out in @oacjournal.bsky.social: shorturl.at/Yii8H Skytorial 👇 #neuroskyence
July 19, 2025 at 10:25 AM
Our #PainResearch paper showing that sphingomyelin 34:1 (⬆️ in 🧍osteoarthritis synovial fluid) sensitises 🐁 sensory neurons in vitro & causes pain behaviours + knee-innervating neuronal hyperexcitability in 🐁 in vivo is now out in @oacjournal.bsky.social: shorturl.at/Yii8H Skytorial 👇 #neuroskyence
Reposted by Wing Yui Ngan
OrthoFinder just dropped a major update
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
July 16, 2025 at 5:51 PM
OrthoFinder just dropped a major update
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
Enjoyed the @phar.cam.ac.uk department final year talk last Friday. @psalmotoxin.bsky.social Smith Team delivered 5 talks from IBD & pain (Luke), joint pain (Helen and Monica), ageing (Cherry) to gut barrier functions (Anne). Wow 👏👏👏.
July 14, 2025 at 7:17 AM
Enjoyed the @phar.cam.ac.uk department final year talk last Friday. @psalmotoxin.bsky.social Smith Team delivered 5 talks from IBD & pain (Luke), joint pain (Helen and Monica), ageing (Cherry) to gut barrier functions (Anne). Wow 👏👏👏.
Reposted by Wing Yui Ngan
The new version of MetaPhlAn v4.2.2 released!
📌taxonomic profiling of long-read metagenomes for the first time
📌new version of the MetaPhlAn db (vJan25_202503) containing >21k new SGBs
Try it out & @hutlab.bsky.social and we are looking forward to your feedback!
forum.biobakery.org/t/metaphlan-...
📌taxonomic profiling of long-read metagenomes for the first time
📌new version of the MetaPhlAn db (vJan25_202503) containing >21k new SGBs
Try it out & @hutlab.bsky.social and we are looking forward to your feedback!
forum.biobakery.org/t/metaphlan-...
MetaPhlAn 4.2.2 release (initial long-read sequencing support and database update)
Announcement We are pleased to share that MetaPhlAn 4.2.2 is now available, which incorporates taxonomic profiling of long-read metagenomes for the first time and includes a new version of the MetaPhl...
forum.biobakery.org
June 11, 2025 at 6:15 AM
The new version of MetaPhlAn v4.2.2 released!
📌taxonomic profiling of long-read metagenomes for the first time
📌new version of the MetaPhlAn db (vJan25_202503) containing >21k new SGBs
Try it out & @hutlab.bsky.social and we are looking forward to your feedback!
forum.biobakery.org/t/metaphlan-...
📌taxonomic profiling of long-read metagenomes for the first time
📌new version of the MetaPhlAn db (vJan25_202503) containing >21k new SGBs
Try it out & @hutlab.bsky.social and we are looking forward to your feedback!
forum.biobakery.org/t/metaphlan-...
Reposted by Wing Yui Ngan
Great to have you on board! If the project runs as smoothly as the punting, we’ll be sorted, exciting ties ahead 😃
June 8, 2025 at 11:32 AM
Great to have you on board! If the project runs as smoothly as the punting, we’ll be sorted, exciting ties ahead 😃
Excited to have started my postdoc with @psalmotoxin.bsky.social, working on mole rat research! Got a really warm welcome from the team 😄🙌
Wrapped up the first week with some lab punting on Friday—strong start! (Mole rats weren't invited but we had a blast anyway 🛶)
Wrapped up the first week with some lab punting on Friday—strong start! (Mole rats weren't invited but we had a blast anyway 🛶)
June 8, 2025 at 11:13 AM
Excited to have started my postdoc with @psalmotoxin.bsky.social, working on mole rat research! Got a really warm welcome from the team 😄🙌
Wrapped up the first week with some lab punting on Friday—strong start! (Mole rats weren't invited but we had a blast anyway 🛶)
Wrapped up the first week with some lab punting on Friday—strong start! (Mole rats weren't invited but we had a blast anyway 🛶)
Summary: Lavisha found an IS inserted next to a deletion, and I found an IS inserted between two duplication fragments. Interestingly, both have no target site duplications identified.
It suggested 1) IS element inserted in the DNA break, or 2) the Del or Dup was mediated by the IS transposase.
It suggested 1) IS element inserted in the DNA break, or 2) the Del or Dup was mediated by the IS transposase.
Our paper recently was published. It's about insertion sequences in relation to large scale DNA duplications and deletions. I'll try to write a summary soon but things are busy!
Led by Jenna Gallie and Frederic Bertels. Guy and I learned a lot! Please share :D
journals.asm.org/doi/10.1128/...
Led by Jenna Gallie and Frederic Bertels. Guy and I learned a lot! Please share :D
journals.asm.org/doi/10.1128/...
A more significant role for insertion sequences in large-scale rearrangements in bacterial genomes | mBio
Insertion sequences are the most common mobile genetic elements found in bacterial
genomes, and hence they significantly impact bacterial evolution. We observe insertion
sequence movement at the cente...
journals.asm.org
December 7, 2024 at 5:13 PM
Summary: Lavisha found an IS inserted next to a deletion, and I found an IS inserted between two duplication fragments. Interestingly, both have no target site duplications identified.
It suggested 1) IS element inserted in the DNA break, or 2) the Del or Dup was mediated by the IS transposase.
It suggested 1) IS element inserted in the DNA break, or 2) the Del or Dup was mediated by the IS transposase.
Delighted to contribute to this project and grateful that part of my PhD work builds upon the findings in this paper.
As I near the completion of my PhD journey, stay tuned for the updates and sharing of my research. 🙌
As I near the completion of my PhD journey, stay tuned for the updates and sharing of my research. 🙌
Glad to share our work with Dr. Jenna Gallie's group! The study reports on the mechanism of how the tRNA gene repertoire can become flexible within a population level, which was originally considered to be much more stable. Great job, @guyngan.bsky.social !
#MicroSky #EvoSky
#MicroSky #EvoSky
Large-scale duplication events underpin population-level flexibility in tRNA gene copy number in Pseudomonas fluorescens SBW25
Abstract. The complement of tRNA genes within a genome is typically considered to be a (relatively) stable characteristic of an organism. Here, we demonstrate t
academic.oup.com
February 12, 2024 at 6:36 PM
Delighted to contribute to this project and grateful that part of my PhD work builds upon the findings in this paper.
As I near the completion of my PhD journey, stay tuned for the updates and sharing of my research. 🙌
As I near the completion of my PhD journey, stay tuned for the updates and sharing of my research. 🙌