Alessandro Zunino
@zuninoale.bsky.social
69 followers 97 following 16 posts
Physicist interested in classical and quantum optics. All-around climber and amateur alpinist. https://alessandro-zunino.github.io/
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zuninoale.bsky.social
Our last paper on s²ISM (super-resolution sectioning #ImageScanningMicroscopy) just got published on Nature Photonics @natphoton.nature.com‬! Discover how structured detection in laser scanning microscopes enhances both resolution and optical sectioning:

www.nature.com/articles/s41...

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Reposted by Alessandro Zunino
vicidominilab.bsky.social
Andrea Bucci and Laurent Le will run two workshops on building a custom #PhotonResolvedMicroscopy system and generating great #ImageScanningMicroscopy images.
Thanks @iitalk.bsky.social @erc.europa.eu @genoainstruments.bsky.social and #PNRR RNA&GeneTheraphy for support. See you at #Mifobio2025
Reposted by Alessandro Zunino
gdrimabio.bsky.social
#Mifobio2025
Focus on the module 2 :
👉 the challenges of spatial and temporal quantification

We are delighted to welcome Dr. Giuseppe VICIDOMINI @vicidominilab.bsky.social @iitalk.bsky.social

Lecture - “Photon-Resolved Microscopy : Image-Scanning Microscopy with SPAD Array Detector and Beyond”
Reposted by Alessandro Zunino
elislenders.bsky.social
Very happy to be in #ThePhotonics100 list for 2026. Big thanks to everyone in @vicidominilab.bsky.social and to all collaborators for their continuous support!
Reposted by Alessandro Zunino
biorxiv-biophys.bsky.social
Interferometric Image Scanning Microscopy for label-free imaging at 120 nm resolution inside live cells https://www.biorxiv.org/content/10.1101/2025.09.19.677416v1
Reposted by Alessandro Zunino
Reposted by Alessandro Zunino
sylvaingigan.bsky.social
and... our program for the upcoming IMAGE SCIENCE🔬 Gordon Research Conference (GRC) is 🎯LIVE🎯. It will take place April 26, 2026 in beautiful tuscany, italy 🇮🇹 🍕 🤌

Please check our stellar line-up, share, and register!

www.grc.org/image-scienc...
2026 Image Science Conference GRC
The 2026 Gordon Research Conference on Image Science will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
www.grc.org
zuninoale.bsky.social
We have a FRC module in our Python package: brighteyes-ism.readthedocs.io
Reposted by Alessandro Zunino
vicidominilab.bsky.social
“A #SPADarray in any laser scanning #microscope”. That is the latest effort from a group of people that shared this mantra. Proud of all of them.
@erc.europa.eu
#imagescanningmicroscopy #photonresolvedmicroscopy
#superresolution
#BrightEyes_ERC

doi.org/10.1038/s415...
zuninoale.bsky.social
Traveling Salesman Problem?
Reposted by Alessandro Zunino
vicidominilab.bsky.social
#ISMFLUX shows #SPADarray is the future of #MINFLUX, improving localisation robustness and enabling the transformation of a #confocal #microscope into a #MINFLUX system.
www.nature.com/articles/s41...
#photonresolvedmicroscopy #BrightEyes_ERC
@iitalk.bsky.social @erc.europa.eu @ec.europa.eu
Reposted by Alessandro Zunino
elislenders.bsky.social
Excited to share our paper on ISM-FLUX, our new #MINFLUX-based technology. Achieve sub-10 nm localization uncertainty on single molecules using a straightforward #confocal-based setup with an array detector. 1/6 www.nature.com/articles/s41...
Array detection enables large localization range for simple and robust MINFLUX - Light: Science & Applications
Light: Science & Applications - Array detection enables large localization range for simple and robust MINFLUX
www.nature.com
zuninoale.bsky.social
God does not play dice with the universe?
Reposted by Alessandro Zunino
rmsearlycareer.bsky.social
Alessandro Zunino now describes contributions to the Image Scanning Microscope (s^2-ISM) for super-res 3D sectioning much like SIM, and FLIM-capable but with a small confocal photodiode array!
Reposted by Alessandro Zunino
vicidominilab.bsky.social
It is time to update our #photonresolvedmicroscope to make it more #smart, and we are looking for a PhD candidate. Here are the application details
vicidominilab.github.io/positions/
If you are interested, please get in touch with me.
@iitalk.bsky.social
#superresolution #microscopy #SPADarray
zuninoale.bsky.social
I smell Richardson-Lucy, here.
Reposted by Alessandro Zunino
zuninoale.bsky.social
Our last paper on s²ISM (super-resolution sectioning #ImageScanningMicroscopy) just got published on Nature Photonics @natphoton.nature.com‬! Discover how structured detection in laser scanning microscopes enhances both resolution and optical sectioning:

www.nature.com/articles/s41...

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zuninoale.bsky.social
This work was made possible thanks to my amazing colleagues at the @vicidominilab.bsky.social in @iitalk.bsky.social . It is part of the #BrightEyes_ERC project funded by @erc.europa.eu. If you are curious about what else is cooking in the pot, check out our website:

vicidominilab.github.io

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zuninoale.bsky.social
Curious to try it out? You can! Our code is completely free and open source, and our data is available for download. You can find the ready-to-use Python package with examples and documentation here:

github.com/VicidominiLa...

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GitHub - VicidominiLab/s2ISM
Contribute to VicidominiLab/s2ISM development by creating an account on GitHub.
github.com
zuninoale.bsky.social
The benefits of s²ISM extend to any other additional dimension contained in the ISM dataset, such as time and spectrum. We demonstrate superior fluorescence lifetime imaging, enabled by the single-photon timing capabilities of the #SPADarray and strengthened by our approach.

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