Immune activity at the cerebrospinal fluid (CSF)–dura–brain interface regulates key functions of brain physiology. In two back-to-back papers, Mamuladze et al. and Kothari et al. show that dural mast cells (MCs) are strategically positioned to coordinate this regulation, controlling CSF flow dynamics and immune cell trafficking in allergy, meningitis, and stroke.

Specialized macrophages are known to persist within tissue niches, but the molecular mechanisms guiding their sustained functional adaptation remain unclear. Kolter and Döring et al. show that local interactions between sensory nerves and macrophages activate TGF-β, which imprints and maintains nerve-associated macrophages that contribute to regeneration after tissue injury.

Pioneering project uses “rapid autopsies” to find virus hideouts in infected people

The causes of early-life eczema have been unclear, but evidence indicates that changes to fetal immune cells and sensory neurons during pregnancy play a key part.

An unprecedented situation has arisen this summer, with the first locally acquired cases of chikungunya detected as early as June, notably affecting the Grand Est region for the very first time. Chiku...

From the tiger mosquito, now well established in Europe, to endemic species in the tropics or Pacific region, these insects have colonized vast areas of the planet and play a key role in local ecosyst...

Humanities and Social Sciences Communications - The innovation trade-off: how following superstars shapes academic novelty

YouTube video by European Commission