Very interesting paper. Proteosomes generate anti-microbial peptides in response to infection. It may well be previously unknown mechanism of innate immunity and source of new antibiotics. www.nature.com/articles/s41...
Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature
Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...
www.nature.com
March 6, 2025 at 6:26 AM
Very interesting paper. Proteosomes generate anti-microbial peptides in response to infection. It may well be previously unknown mechanism of innate immunity and source of new antibiotics. www.nature.com/articles/s41...
Great news! Photos are taken under blue sky (no pun intended) which is rare occurrance in mid-Wales. Did they have to wait for a good day to run this test? Does it work in normal Welsh conditions. I hope it does, we need it and yes we should share it with people who defend all of us in Europe.
The laser was integrated onto a Wolfhound – a protected troop-carrying vehicle - where soldiers from 16 Royal Artillery were able to track and down hovering targets at Radnor Range in mid-Wales.
December 11, 2024 at 1:54 PM
Great news! Photos are taken under blue sky (no pun intended) which is rare occurrance in mid-Wales. Did they have to wait for a good day to run this test? Does it work in normal Welsh conditions. I hope it does, we need it and yes we should share it with people who defend all of us in Europe.
Ironically, the only rock climbing discipline which is not affected by rain is called dry tooling. Enjoyed dry tooling in the rain in Masson Lees quarry above Matlock (photo from session a year ago) this Sunday. #climbing
December 3, 2024 at 5:51 PM
Ironically, the only rock climbing discipline which is not affected by rain is called dry tooling. Enjoyed dry tooling in the rain in Masson Lees quarry above Matlock (photo from session a year ago) this Sunday. #climbing
I don't think she should have resigned over this. Standards of politics must be high, but this is exaggeration.
Louise Haigh has resigned as transport secretary after @SkyNews revealed she has fraud conviction for wrongly reporting work mobile phone stolen in 2013.
She said incident was “mistake” and she’s sorry to leave under these circumstances, but doesn’t want to be distraction.
She said incident was “mistake” and she’s sorry to leave under these circumstances, but doesn’t want to be distraction.
November 29, 2024 at 7:46 AM
I don't think she should have resigned over this. Standards of politics must be high, but this is exaggeration.
I wish I could go there again for water ice climbing and utter beauty of crispy sunny winter. Did not happen this year again. Maybe one day, hopefully before winter dissapears over there too.
November 22, 2024 at 12:44 PM
I wish I could go there again for water ice climbing and utter beauty of crispy sunny winter. Did not happen this year again. Maybe one day, hopefully before winter dissapears over there too.
Taking rest after Olympic season?https://www.ukclimbing.com/news/2024/11/jessy_pilz_climbs_papichulo_9a+-73848
NEWS: Jessy Pilz climbs Papichulo 9a+
Jessy Pilz has made the second female ascent of Papichulo, 9a+, in Oliana, Spain.
www.ukclimbing.com
November 21, 2024 at 1:52 PM
Taking rest after Olympic season?https://www.ukclimbing.com/news/2024/11/jessy_pilz_climbs_papichulo_9a+-73848
Reposted by Andrzej Kierzek
Something that's been bugging me for a while in bioinformatics data analysis is this overreliance on packages, workflows and what's been called "cargo cult science".
Can we have more conceptual thinking, more theory?
Asking for what we really want to achieve and what we need to do gets us there.
Can we have more conceptual thinking, more theory?
Asking for what we really want to achieve and what we need to do gets us there.
November 19, 2024 at 10:58 AM
Something that's been bugging me for a while in bioinformatics data analysis is this overreliance on packages, workflows and what's been called "cargo cult science".
Can we have more conceptual thinking, more theory?
Asking for what we really want to achieve and what we need to do gets us there.
Can we have more conceptual thinking, more theory?
Asking for what we really want to achieve and what we need to do gets us there.
Opening winter climbing season in my Lockdown Memorial Climbing Center. Hope to find winter in Cairngorms when I'm there for my usual February visit and use skills again on a wee bit longer climbs.
November 19, 2024 at 2:28 PM
Opening winter climbing season in my Lockdown Memorial Climbing Center. Hope to find winter in Cairngorms when I'm there for my usual February visit and use skills again on a wee bit longer climbs.
Brilliant! Thank you for that!
Do you ever get the feeling the world’s gone crazy? With this in mind, I play the Flintstones theme in the style of the Russian classics.
November 18, 2024 at 8:20 AM
Brilliant! Thank you for that!
Welcome to BlueSky. It was good to climb on my local Millstone crag last week. I would not mind a bit bluer sky, and a bit dryer rock, but it was still good, espcially now that I can crack climb.
November 17, 2024 at 2:54 PM
Welcome to BlueSky. It was good to climb on my local Millstone crag last week. I would not mind a bit bluer sky, and a bit dryer rock, but it was still good, espcially now that I can crack climb.