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Aaron Klausnitzer

@aklausnitzer.bsky.social

120 followers 110 following 5 posts

PhD student @ Glaubitz lab / membrane transport proteins / lipopolysaccharide transport / solid-state NMR #sfb1507

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Aaron Klausnitzer @aklausnitzer.bsky.social · 15d

Proud that our work is online now in @jacs.acspublications.org 🎉 A big thanks to everyone involved in this project! If you are interested have a read:

doi.org/10.1021/jacs...

Conformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB2FGC Complex

The outer membrane of Gram-negative bacteria is coated with lipopolysaccharide (LPS). The Lpt system generates membrane asymmetry by transporting LPS from the inner to the outer membrane. Transport be...

doi.org

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Aaron Klausnitzer @aklausnitzer.bsky.social · 15d

Proud that our work is online now in @jacs.acspublications.org 🎉 A big thanks to everyone involved in this project! If you are interested have a read:

doi.org/10.1021/jacs...

Conformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB2FGC Complex

doi.org

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Aaron Klausnitzer @aklausnitzer.bsky.social · Jul 12

Thank you Ute!😊
Best TAC Committee out there!😬

Aaron Klausnitzer @aklausnitzer.bsky.social · Jul 12

Very happy to Share that my First paper has been uploaded on bioRxiv 🥳 This was a large team effort together with Jagdeep! We took the next steps into understanding how lipopolysaccharides are transported by the LptB2FGC complex with NMR🧲

bioRxivpreprint @biorxivpreprint.bsky.social · Jul 12

Conformational plasticity of LptC regulates lipopolysaccharide transportby the LptB2FGC complex https://www.biorxiv.org/content/10.1101/2025.07.09.663713v1

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Aaron Klausnitzer @aklausnitzer.bsky.social · May 13

Congrats David 🥳

Reposted by Aaron Klausnitzer

David Griwatz @davidgriwatz.bsky.social · May 13

Proud to share this great story is out now! A huge Thank You to the whole team but especially to my co-first author Janina Stautz. The results were often surprising but we managed to unpuzzle how a short IDR and its membrane interaction are involved in channel opening.

Inga Hänelt @ihaenelt.bsky.social · May 12

This took us a while and I am all the happier it is finally out! I thought that simply adding ATP to purified potassium channel KtrAB should be sufficient to stabilize its active state. I was so wrong...
Read the full story on how an IDR facilitates channel opening upon membrane interaction.

A short intrinsically disordered region at KtrB’s N-terminus facilitates allosteric regulation of K+ channel KtrAB

Nature Communications - KtrAB is a major potassium uptake system that has been linked to the pathogenesis of many infectious bacteria. Here the authors show that KtrB from Vibrio alginolyticus...

www.nature.com

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Reposted by Aaron Klausnitzer

Ute Hellmich @hellmichgroup.bsky.social · Mar 3

So proud that our very own Victor won a poster award for his amazing work on bidirectional coupling in an ABC transporter at #ABC2025!
😍🥳🥳🥳🥳

read more here:
www.biorxiv.org/content/10.1...

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Aaron Klausnitzer @aklausnitzer.bsky.social · Feb 28

I‘m happy that i could share my project on this years #ABC2025😊

ABC2025 @abcmeeting.bsky.social · Feb 28

After a great talk from Agatha Tymczak from Voula Kanelis lab using solution NMR on SUR1, @aklausnitzer.bsky.social presenting now on the power of solid-state NMR to study ABC transporters! #ABC2025
And chair Maki Tsujita keeping everyone on time 😅

Reposted by Aaron Klausnitzer

evlodinsky.bsky.social @evlodinsky.bsky.social · Jan 29

Hello Bluesky, excited to be here🌟 For my first post, I wanted to share our recent collaboration, which I was very happy to contribute to. Our findings indicate that Camalexin could serve as a promising scaffold for developing potent inhibitors against AcrB. Have a read here: doi.org/10.1016/j.bi...

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doi.org

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