Alba Nieto Heredia
@albanietoh.bsky.social
PhD Student MSCMSCA-Horizon2020 AI4theSciences.
IBE - PSL
🍂 PopGen with a sprinkle of AI 🍂
IBE - PSL
🍂 PopGen with a sprinkle of AI 🍂
Pinned
Performance of Sequential Markovian Coalescence Methods when Populations are Structured https://www.biorxiv.org/content/10.1101/2025.10.09.681379v1
Take a look at my first preprint as a first author!
We analyse the effect of population structure in SMC methods and find two systematic biases that have indeed extra information about the population! We model the nature of these biases and find a link with the isolation of the population and Fst.
We analyse the effect of population structure in SMC methods and find two systematic biases that have indeed extra information about the population! We model the nature of these biases and find a link with the isolation of the population and Fst.
Take a look at my first preprint as a first author!
We analyse the effect of population structure in SMC methods and find two systematic biases that have indeed extra information about the population! We model the nature of these biases and find a link with the isolation of the population and Fst.
We analyse the effect of population structure in SMC methods and find two systematic biases that have indeed extra information about the population! We model the nature of these biases and find a link with the isolation of the population and Fst.
Performance of Sequential Markovian Coalescence Methods when Populations are Structured https://www.biorxiv.org/content/10.1101/2025.10.09.681379v1
October 11, 2025 at 4:22 PM
Take a look at my first preprint as a first author!
We analyse the effect of population structure in SMC methods and find two systematic biases that have indeed extra information about the population! We model the nature of these biases and find a link with the isolation of the population and Fst.
We analyse the effect of population structure in SMC methods and find two systematic biases that have indeed extra information about the population! We model the nature of these biases and find a link with the isolation of the population and Fst.
Reposted by Alba Nieto Heredia
Excited to share our new preprint🙌
It's the first human WGS study in Sudan. We uncover one of the strongest selection signals to date, pointing to post-admixture adaptation to malaria in Copts. Huge thanks to all co-authors. @aidaandres.bsky.social @jgarcia-cal.bsky.social @ebosch1972.bsky.social
It's the first human WGS study in Sudan. We uncover one of the strongest selection signals to date, pointing to post-admixture adaptation to malaria in Copts. Huge thanks to all co-authors. @aidaandres.bsky.social @jgarcia-cal.bsky.social @ebosch1972.bsky.social
Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts https://www.medrxiv.org/content/10.1101/2025.09.01.25334828v1
September 3, 2025 at 8:24 AM
Excited to share our new preprint🙌
It's the first human WGS study in Sudan. We uncover one of the strongest selection signals to date, pointing to post-admixture adaptation to malaria in Copts. Huge thanks to all co-authors. @aidaandres.bsky.social @jgarcia-cal.bsky.social @ebosch1972.bsky.social
It's the first human WGS study in Sudan. We uncover one of the strongest selection signals to date, pointing to post-admixture adaptation to malaria in Copts. Huge thanks to all co-authors. @aidaandres.bsky.social @jgarcia-cal.bsky.social @ebosch1972.bsky.social
That somehow truly happened 1 month ago. #SMBE2025 has been amazing and being part of the Excellence Graduate Awarded is nothing less than a dream come true
August 21, 2025 at 9:00 AM
That somehow truly happened 1 month ago. #SMBE2025 has been amazing and being part of the Excellence Graduate Awarded is nothing less than a dream come true
July 22, 2025 at 8:50 AM
An experience I will never forget!
After a week of intense population genomics, lots of tired but still smiley faces. Thank you @embo.org for funding another edition of our Population Genomics course in Naples. And thank you to the trainers and participants for making this eight edition another success! #EMBOpopgen
June 29, 2025 at 3:59 PM
An experience I will never forget!
They did it! They opened the path to overcome the assumptions the of SMC-based coalescent with LLMs. This new era is just right here!
Coalescence and Translation: A Language Model for Population Genetics https://www.biorxiv.org/content/10.1101/2025.06.24.661337v1
June 29, 2025 at 3:51 PM
They did it! They opened the path to overcome the assumptions the of SMC-based coalescent with LLMs. This new era is just right here!
Seeing how every effort has now materialized into lessons and teachings that truly benefit @ibe-barcelona.bsky.social scientists of all generations has been immeasurable. Thank you, @xavimartiperez.bsky.social, for co-leading this project.
📣Today the #IBE_Barcelona Students Committee organizes the #IBEWorkshop, a new initiative aimed at fostering knowledge exchange, skill development, and community building across all levels of the institute.🤩
#UnravellingEvolution
#DiscoveringLife
#ConservingBiodiversity
#UnravellingEvolution
#DiscoveringLife
#ConservingBiodiversity
June 16, 2025 at 9:17 PM
Seeing how every effort has now materialized into lessons and teachings that truly benefit @ibe-barcelona.bsky.social scientists of all generations has been immeasurable. Thank you, @xavimartiperez.bsky.social, for co-leading this project.
Reposted by Alba Nieto Heredia
Excited for our publication on how the geographic scale of a sample affects the discovery of rare, deleterious variants to be out this week. With a mix of theory, simulation, and data analysis, we show when samples are narrow vs broad, the number of variants discovered and their frequencies change
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
June 5, 2025 at 5:55 PM
Excited for our publication on how the geographic scale of a sample affects the discovery of rare, deleterious variants to be out this week. With a mix of theory, simulation, and data analysis, we show when samples are narrow vs broad, the number of variants discovered and their frequencies change
Very happy to have been part of this project. Go check this dive on SMC-based models!
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv: arxiv.org/abs/2506.00692 (based on last year's @official-smbe.bsky.social symposium)
Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...
arxiv.org
June 16, 2025 at 6:19 AM
Very happy to have been part of this project. Go check this dive on SMC-based models!
Reposted by Alba Nieto Heredia
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv: arxiv.org/abs/2506.00692 (based on last year's @official-smbe.bsky.social symposium)
Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...
arxiv.org
June 11, 2025 at 5:18 PM
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv: arxiv.org/abs/2506.00692 (based on last year's @official-smbe.bsky.social symposium)
Reposted by Alba Nieto Heredia
Talks by: @dylansosa.bsky.social @aidanwshort.bsky.social @gemmaeling.bsky.social @hverdonk.bsky.social @Kaiyuan Li @philipphummer.bsky.social Huangyi He @albanietoh.bsky.social
June 9, 2025 at 5:14 PM
Talks by: @dylansosa.bsky.social @aidanwshort.bsky.social @gemmaeling.bsky.social @hverdonk.bsky.social @Kaiyuan Li @philipphummer.bsky.social Huangyi He @albanietoh.bsky.social
Reposted by Alba Nieto Heredia
Any young paleo workers will be hard pressed to find a better opportunity than this.
Come postdoc in Oslo! 3 years. You design the project! Get in touch with me or others at our museum! Deadline 23 june www.jobbnorge.no/en/available... share and repost !
Postdoctoral Fellow: Self-Developed Project (280531) | University of Oslo
Job title: Postdoctoral Fellow: Self-Developed Project (280531), Employer: University of Oslo, Deadline: Monday, June 23, 2025
www.jobbnorge.no
May 21, 2025 at 5:28 AM
Any young paleo workers will be hard pressed to find a better opportunity than this.
Reposted by Alba Nieto Heredia
@albanietoh.bsky.social , doctorante
@psl-univ.bsky.social
Elle mène ses recherches entre
@isyeb.mnhn.fr au #MNHN Paris et
@ibe-barcelona.bsky.social à Barcelone"
lauréate ▶️ graduate studient excellence award
@official-smbe.bsky.social ! 🏆
@psl-univ.bsky.social
Elle mène ses recherches entre
@isyeb.mnhn.fr au #MNHN Paris et
@ibe-barcelona.bsky.social à Barcelone"
lauréate ▶️ graduate studient excellence award
@official-smbe.bsky.social ! 🏆
Our latest GSEA winner is Alba Nieto Heredia, PhD student @psl-univ.bsky.social
Alba's popgen and computational biology research focuses on population structure and its critical role in demographic inference.
More on Alba ⬇️ and follow her: @albanietoh.bsky.social
Alba's popgen and computational biology research focuses on population structure and its critical role in demographic inference.
More on Alba ⬇️ and follow her: @albanietoh.bsky.social
May 13, 2025 at 12:54 PM
@albanietoh.bsky.social , doctorante
@psl-univ.bsky.social
Elle mène ses recherches entre
@isyeb.mnhn.fr au #MNHN Paris et
@ibe-barcelona.bsky.social à Barcelone"
lauréate ▶️ graduate studient excellence award
@official-smbe.bsky.social ! 🏆
@psl-univ.bsky.social
Elle mène ses recherches entre
@isyeb.mnhn.fr au #MNHN Paris et
@ibe-barcelona.bsky.social à Barcelone"
lauréate ▶️ graduate studient excellence award
@official-smbe.bsky.social ! 🏆
Reposted by Alba Nieto Heredia
Indigenous researchers and communities are reshaping how Western science thinks about data ownership. #AANHPIHeritageMonth scim.ag/4m5VBJZ
‘Not a free-for-all’: Indigenous communities want limits on how their data are shared
Push for “data sovereignty” could reshape how scientists share information
scim.ag
May 8, 2025 at 9:24 PM
Indigenous researchers and communities are reshaping how Western science thinks about data ownership. #AANHPIHeritageMonth scim.ag/4m5VBJZ
Feeling truly honored and grateful to be recognized by @official-smbe.bsky.social with this award! Looking forward to see you all in #SMBE2025 in Beijing!
For those who want to know more about Darwin's statue ⬇️⬇️
For those who want to know more about Darwin's statue ⬇️⬇️
Our latest GSEA winner is Alba Nieto Heredia, PhD student @psl-univ.bsky.social
Alba's popgen and computational biology research focuses on population structure and its critical role in demographic inference.
More on Alba ⬇️ and follow her: @albanietoh.bsky.social
Alba's popgen and computational biology research focuses on population structure and its critical role in demographic inference.
More on Alba ⬇️ and follow her: @albanietoh.bsky.social
May 8, 2025 at 4:59 PM
Feeling truly honored and grateful to be recognized by @official-smbe.bsky.social with this award! Looking forward to see you all in #SMBE2025 in Beijing!
For those who want to know more about Darwin's statue ⬇️⬇️
For those who want to know more about Darwin's statue ⬇️⬇️
Reposted by Alba Nieto Heredia
🐜 Today's GSEA focus is on Gemma Martínez Redondo, PhD candidate @ub.edu
Gemma's research combines traditional phylogenetics, phylogenomics, and machine learning to understand the genomic basis of terrestrialization across animals
More on Gemma ⬇️ and follow her: @gemmaeling.bsky.social
Gemma's research combines traditional phylogenetics, phylogenomics, and machine learning to understand the genomic basis of terrestrialization across animals
More on Gemma ⬇️ and follow her: @gemmaeling.bsky.social
May 5, 2025 at 8:07 AM
🐜 Today's GSEA focus is on Gemma Martínez Redondo, PhD candidate @ub.edu
Gemma's research combines traditional phylogenetics, phylogenomics, and machine learning to understand the genomic basis of terrestrialization across animals
More on Gemma ⬇️ and follow her: @gemmaeling.bsky.social
Gemma's research combines traditional phylogenetics, phylogenomics, and machine learning to understand the genomic basis of terrestrialization across animals
More on Gemma ⬇️ and follow her: @gemmaeling.bsky.social
Don't miss this study on selection using a Catalan cohort of Spanish Population! Catalonia is a region in the north of the Iberian Peninsula with a rich history of recent migration from all the Spanish geography. They made the most of the data with an historical context of popstructure!
I am delighted to share with you some new insights into the selection processes that shaped the Spanish population!
This work has been led by @ebosch1972.bsky.social @francesccalafell.bsky.social ( @upf.edu ) in collaboration with Rafael de Cid ( @igtp.bsky.social ) and @sabiagini.bsky.social
⬇️⬇️⬇️
This work has been led by @ebosch1972.bsky.social @francesccalafell.bsky.social ( @upf.edu ) in collaboration with Rafael de Cid ( @igtp.bsky.social ) and @sabiagini.bsky.social
⬇️⬇️⬇️
Inferring past demography and genetic adaptation in Spain using the GCAT cohort - Scientific Reports
Scientific Reports - Inferring past demography and genetic adaptation in Spain using the GCAT cohort
www.nature.com
April 25, 2025 at 5:10 PM
Don't miss this study on selection using a Catalan cohort of Spanish Population! Catalonia is a region in the north of the Iberian Peninsula with a rich history of recent migration from all the Spanish geography. They made the most of the data with an historical context of popstructure!
So Happy for the warm welcome or our PopGen bookclub! Each month, at IBE, we review a new chapter of @gcbias.bsky.social book, which is totally open-source! We encourage you to take a look at it! Link: github.com/cooplab/popg...
April 25, 2025 at 2:24 PM
So Happy for the warm welcome or our PopGen bookclub! Each month, at IBE, we review a new chapter of @gcbias.bsky.social book, which is totally open-source! We encourage you to take a look at it! Link: github.com/cooplab/popg...
Reposted by Alba Nieto Heredia
Join us for ARGEvol, a conference on ancestral recombination graphs in Vila do Conde, Portugal from Nov 12-14, 2025. Complete the interest survey: https://framaforms.org/argevol-conferenceworkshop-interest-survey-1742308127. #conference
April 16, 2025 at 7:58 AM
Join us for ARGEvol, a conference on ancestral recombination graphs in Vila do Conde, Portugal from Nov 12-14, 2025. Complete the interest survey: https://framaforms.org/argevol-conferenceworkshop-interest-survey-1742308127. #conference
Reposted by Alba Nieto Heredia
The April cover of Molecular Biology and Evolution features the work of Menno de Jong et al., who analysed autosomal and sex chromosomal data to reconstruct the demographic history of the Red deer.
Link: doi.org/10.1093/molb...
📷 Bas Worm
#evolution #reddeer
Link: doi.org/10.1093/molb...
📷 Bas Worm
#evolution #reddeer
April 9, 2025 at 7:16 PM
The April cover of Molecular Biology and Evolution features the work of Menno de Jong et al., who analysed autosomal and sex chromosomal data to reconstruct the demographic history of the Red deer.
Link: doi.org/10.1093/molb...
📷 Bas Worm
#evolution #reddeer
Link: doi.org/10.1093/molb...
📷 Bas Worm
#evolution #reddeer
Reposted by Alba Nieto Heredia
📢 Recipients of the SMBE Graduate Student Excellence Award have been selected and contacted by email. The society is impressed by their outstanding research and invites them to attend SMBE2025 in Beijing.
In the upcoming weeks, we will highlight the recipients and their research. Stay tuned!
In the upcoming weeks, we will highlight the recipients and their research. Stay tuned!
April 14, 2025 at 2:03 PM
📢 Recipients of the SMBE Graduate Student Excellence Award have been selected and contacted by email. The society is impressed by their outstanding research and invites them to attend SMBE2025 in Beijing.
In the upcoming weeks, we will highlight the recipients and their research. Stay tuned!
In the upcoming weeks, we will highlight the recipients and their research. Stay tuned!
Reposted by Alba Nieto Heredia
📝 Excited to share this work!We revealed significant genetic isolation and unique demographic patterns in the Raute, the last nomadic hunter-gatherer population of the Himalayas! 🏔️🧬
✨ Big thanks to the team, and kudos to Dr. Inez Derks 🎉
🔗 Check it out! #AcademicSky
www.nature.com/articles/s41...
✨ Big thanks to the team, and kudos to Dr. Inez Derks 🎉
🔗 Check it out! #AcademicSky
www.nature.com/articles/s41...
The genetic demographic history of the last hunter-gatherer population of the Himalayas
Scientific Reports - The genetic demographic history of the last hunter-gatherer population of the Himalayas
www.nature.com
January 9, 2025 at 4:55 PM
📝 Excited to share this work!We revealed significant genetic isolation and unique demographic patterns in the Raute, the last nomadic hunter-gatherer population of the Himalayas! 🏔️🧬
✨ Big thanks to the team, and kudos to Dr. Inez Derks 🎉
🔗 Check it out! #AcademicSky
www.nature.com/articles/s41...
✨ Big thanks to the team, and kudos to Dr. Inez Derks 🎉
🔗 Check it out! #AcademicSky
www.nature.com/articles/s41...
Reposted by Alba Nieto Heredia
This just out! rdcu.be/d5ptO. We compared SNP arrays and exomes in Eivissans and Minorcans, found that drift was way more intense in the former than in the latter, although, fortunately, Eivissans did not accumulate more deleterious mutations (1/2)
A reduction in effective population size has not relaxed purifying selection in the human population of Eivissa (Balearic Islands)
Scientific Reports - A reduction in effective population size has not relaxed purifying selection in the human population of Eivissa (Balearic Islands)
rdcu.be
January 3, 2025 at 11:28 AM
This just out! rdcu.be/d5ptO. We compared SNP arrays and exomes in Eivissans and Minorcans, found that drift was way more intense in the former than in the latter, although, fortunately, Eivissans did not accumulate more deleterious mutations (1/2)
Reposted by Alba Nieto Heredia
A pleasure to have presented my work on polygenic adaptation in human European populations at the XII Jornada de Bioinformàtica, organized by @scb.iec.cat in Lleida.
#Genomics
#NaturalSelection
#PolygenicAdaptation
#Genomics
#NaturalSelection
#PolygenicAdaptation
December 16, 2024 at 1:22 PM
A pleasure to have presented my work on polygenic adaptation in human European populations at the XII Jornada de Bioinformàtica, organized by @scb.iec.cat in Lleida.
#Genomics
#NaturalSelection
#PolygenicAdaptation
#Genomics
#NaturalSelection
#PolygenicAdaptation
Happy to share our work in preparation in Bioinformatics and Genomics Journeys from @scb.iec.cat in Lleida!
December 13, 2024 at 8:51 PM
Happy to share our work in preparation in Bioinformatics and Genomics Journeys from @scb.iec.cat in Lleida!