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Cutting-edge research, news, commentary, and visuals from the Science family of journals. https://www.science.org
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This image shows 3D, millimeter-thick, and cell-embeddable semiconducting hydrogel fibers.

These fibers can be used to construct interwoven living transistors that mimic real neuronal connections in the brain, redefining the boundary between technology and life. Learn more: https://scim.ag/4rqTOCj
"By successfully integrating [AI] into research workflows, researchers could substantially increase scientific productivity … the US Genesis Mission sparks a critical conversation about how to realize this potential," write Darío Gil and Kathryn Moler in a #ScienceEditorial. https://scim.ag/3XVrZUN
November 25, 2025 at 4:28 PM
Reposted by Science Magazine
Anyone else hear "boop" every time this finger presses on this transistor? Or is it just me? Maybe it's just me... Anyhow, the story of this video and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
November 25, 2025 at 3:52 PM
In a potentially dramatic change to how it chooses what science to fund, NIH is ending a long-running practice at many of its institutes of establishing, and making public, a threshold peer-review score needed for a grant application’s approval. https://scim.ag/48ck2zu
NIH shake-up to grant decision-making draws concerns of political meddling
Policy drops “paylines” based on peer-review scores and requires geography and other factors to guide approvals
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November 25, 2025 at 3:18 PM
It’s a long shot, but scientists may have spotted exotic primordial black holes formed just after the Big Bang. https://scim.ag/43QhxBD
Curious gravitational wave may hint at primordial black holes—or just be noise
Astronomers approach unusual observation with caution and excitement
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November 24, 2025 at 11:30 PM
A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study in Science.

The findings suggest potential for new treatment strategies. https://scim.ag/4rjvjqA
An Aeromonas variant that produces aerolysin promotes susceptibility to ulcerative colitis
Ulcerative colitis (UC) is a severe inflammatory bowel disease affecting millions of people worldwide, but the factors driving the condition are poorly understood. In tissue samples from individuals w...
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November 24, 2025 at 10:00 PM
Studying retinal morphogenesis in the developing eye of fruit flies, researchers in Science identified spontaneous calcium waves originating from non-neuronal cells responsible for orchestrating tissue architecture in the developing nervous system. https://scim.ag/44r2Jtg
Retinal calcium waves coordinate uniform tissue patterning of the Drosophila eye
Optimal neural processing relies on precise tissue patterning across diverse cell types. Here, we show that spontaneous calcium waves arise among non-neuronal support cells in the developing Drosophil...
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November 24, 2025 at 8:45 PM
A new carrier-drug conjugate fuses a TGR5-targeting compound for type 2 #diabetes to silicon particles to limit intestinal absorption, enabling safe and extended blood sugar control in mice and pigs without typical systemic toxicity. #ScienceTranslationalMedicine https://scim.ag/48opIrf
Intestinal TGR5-targeted carrier-drug conjugate improves glycemic control in mice and pigs
A nonabsorbable, intestinal TGR5-targeted conjugate was designed to improve glycemic control while reducing systemic toxicity in mice and pigs.
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November 24, 2025 at 7:39 PM
This superstretchy bloodworm can turn itself inside out.

The marine worm’s unusually structured proboscis could inspire future soft-bodied robots. Learn more: https://scim.ag/48fVqWH
November 24, 2025 at 6:23 PM
Reposted by Science Magazine
🧪 ✏️Apply for the 2026 Diverse Voices in Science Journalism Internship with
@science.org! 🧪 ✏️

This could be for you if you're a student from a community historically underrepresented in #journalism who's interested in in covering science for general audiences: recruiting.ultipro.com/AME1123ASEM/...
recruiting.ultipro.com
November 22, 2025 at 12:00 AM
Reposted by Science Magazine
Origins of language, one of humanity’s most distinctive traits, may be best explained as a unique convergence of multiple capacities each with its own evolutionary history, involving intertwined roles of biology & culture. This framing can expand research horizons. A 🧵 on our @science.org paper.🧪1/n
What enables human language? A biocultural framework
Explaining the origins of language is a key challenge in understanding ourselves as a species. We present an empirical framework that draws on synergies across fields to facilitate robust studies of l...
www.science.org
November 23, 2025 at 11:54 AM
Reposted by Science Magazine
Dive deep into the early history of humans and dogs, this week on the @science.org podcast w/ Life Sciences Editor Sacha Vigniri 🐕🐕‍🦺🐩

www.science.org/content/podc...
November 24, 2025 at 4:59 PM
A new #ScienceRobotics study demonstrates that a domain adaptation framework can control a hip and knee exoskeleton and enable users to lift weights, climb stairs, or run efficiently, with limited or no access to device-specific training data. https://scim.ag/3K35D0v
November 24, 2025 at 5:05 PM
Whether neural organoids feel pain or should be placed in animals are among the questions swirling around biology’s hot new technology. https://scim.ag/3Kh8tPo
Lab-grown models of human brains are advancing rapidly. Can ethics keep pace?
Whether neural organoids feel pain or should be placed in animals are among the questions swirling around biology’s hot new technology
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November 24, 2025 at 3:53 PM
Reposted by Science Magazine
Out First Release in @science.org
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
Pan-family pollen signals control an interspecific stigma barrier across Brassicaceae species
Pre-zygotic interspecific incompatibility prevents hybridization between species limiting interbreeding strategies for crop improvement using wild relatives. The Brassica rapa female self-incompatibil...
www.science.org
November 24, 2025 at 2:45 PM
A magnetically guided microrobotics system is capable of navigating the body’s passageways and vasculature to deliver drugs with pinpoint accuracy, a new study finds in Science.

The system could enable safer, targeted drug treatments that minimize unwanted side effects. https://scim.ag/3LJRXrS
November 23, 2025 at 6:35 PM
Just a few million years after the end-Permian mass extinction event, aquatic reptiles and other vertebrates had recovered to form thriving and diverse oceanic ecosystems, according to a Science study of an Early Triassic-age fossil site in the Arctic.

Learn more: https://scim.ag/4r0k0U1
Earliest oceanic tetrapod ecosystem reveals rapid complexification of Triassic marine communities
Tetrapods invaded oceanic environments after the cataclysmic end-Permian mass extinction (EPME), with temnospondyl amphibian to reptile-dominated assemblages succeeding across the Early Triassic [~251...
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November 22, 2025 at 8:55 PM
In a small study, gene editing slashed blood levels of two fats that contribute to clogged arteries and ramp up risks of heart disease, potentially for life. https://scim.ag/486nL1o
Gene editing cuts blood cholesterol levels in small study
In 15 patients, infusion of CRISPR treatment lowered amounts of two artery-clogging fats
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November 21, 2025 at 11:39 PM
Researchers have developed polymeric nanocultures composed of iron-oxide nanoparticles, providing a field-ready approach for cultivating and studying environmental microbes under near-native conditions.

Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4r90UuS
November 21, 2025 at 10:50 PM
"In the end, I have come to realize that being authentic at work is not a weakness, but rather a strength." #ScienceWorkingLife https://scim.ag/49B7hRv
November 21, 2025 at 8:59 PM
By studying historical oil paintings and artificially aged paint mock-ups, researchers in #ScienceAdvances found that light and humidity trigger distinct degradation pathways for emerald green pigment in paints, offering crucial insights for conservation. https://scim.ag/49ttWPs
Discovering the dual degradation pathway of emerald green in oil paints: The effects of light and humidity
Light and humidity trigger distinct degradation pathways of emerald green in paints, offering crucial insights for conservation.
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November 21, 2025 at 7:17 PM
Reposted by Science Magazine
🧪 ✏️ Apply for the 2026 Diverse Voices in Science Journalism Internship with @science.org! 🧪 ✏️

This could be for you if you're a student from a community historically underrepresented in #journalism who's interested in in covering science for general audiences: recruiting.ultipro.com/AME1123ASEM/...
recruiting.ultipro.com
November 21, 2025 at 6:06 PM
The first study to survey insect populations on a continental scale finds no evidence of widespread decline, at least over a recent 10-year period. https://scim.ag/4pnb6hN
Radar data find no decline in insect numbers—but there’s a catch
Study of continental U.S. sees stable population of bugs, but it may be missing important pieces of the puzzle
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November 21, 2025 at 5:30 PM
A computational platform named CoDIAC reveals new insights about the human SH2 domain and could be applied to many protein domains of interest to interrogate their binding interfaces and molecular interactions.

Learn more in #ScienceSignaling: https://scim.ag/3K8VYp8
CoDIAC: A comprehensive approach for interaction analysis provides insights into SH2 domain function and regulation
An open-source computational pipeline to visualize the binding interfaces of protein domains is described.
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November 21, 2025 at 4:21 PM
Reposted by Science Magazine
Interested in the evolution of human language? Check out our new paper in @science.org where we synthesize latest findings and outline a multifaceted, bio-cultural approach for studying how language evolved. Super proud of this work, and hoping it leads to exciting new research! tinyurl.com/ykacvanp
November 21, 2025 at 9:47 AM
Reposted by Science Magazine
What happened to Europe's first farmers? @andrewcurry.com joins the @science.org podcast to talk about the mass graves linked with the mysterious disappearance of Neolithic LBK culture 7000 years ago.

🎧 Listen here: www.science.org/content/podc...
November 21, 2025 at 1:51 PM