Alberto Sogari
@albertosogari.bsky.social
MD PhD, postdoctoral fellow working on cancer research in the Batlle Lab at IRB Barcelona.
Reposted by Alberto Sogari
1/17 🧵
🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇
➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC).
Very proud of the team and efforts behind it.
www.nature.com/articles/s41...
🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇
➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC).
Very proud of the team and efforts behind it.
www.nature.com/articles/s41...
TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages - Nature Genetics
Targeting TGFBR1 in transplantable mouse colorectal tumor organoids improves response to anti-PD-L1 therapy. Mechanistically, TGF-β abrogates clonal expansion of T effector and memory phenotypes and i...
www.nature.com
November 7, 2025 at 12:30 PM
1/17 🧵
🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇
➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC).
Very proud of the team and efforts behind it.
www.nature.com/articles/s41...
🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇
➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC).
Very proud of the team and efforts behind it.
www.nature.com/articles/s41...
Reposted by Alberto Sogari
Now in Cancer Discovery @aacrjournals.bsky.social: A Plastic EMP1⁺ to LGR5⁺ Cell State Conversion as a Bypass to KRASG12D Inhibition in mCRC - by Alessia Centonze, Adrià-Jaume Rour, Meritxell Novillo-Font, Carme Cortina, Marc Marti-Renom, @batllelab.bsky.social,
et al. doi.org/10.1158/2159...
et al. doi.org/10.1158/2159...
October 23, 2025 at 4:21 PM
Now in Cancer Discovery @aacrjournals.bsky.social: A Plastic EMP1⁺ to LGR5⁺ Cell State Conversion as a Bypass to KRASG12D Inhibition in mCRC - by Alessia Centonze, Adrià-Jaume Rour, Meritxell Novillo-Font, Carme Cortina, Marc Marti-Renom, @batllelab.bsky.social,
et al. doi.org/10.1158/2159...
et al. doi.org/10.1158/2159...
Reposted by Alberto Sogari
A study published in #CancerDiscovery reveals why some colorectal cancers withstand pharmacological inhibition of #KRAS oncogene activity.
Read more here ➡️ https://bit.ly/3L0Cl2G
#CancerResearch olorectalCancer%C2%A0@batllelab.bsky.social%C2%A0" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#ColorectalCancer @batllelab.bsky.social
🧪
Read more here ➡️ https://bit.ly/3L0Cl2G
#CancerResearch olorectalCancer%C2%A0@batllelab.bsky.social%C2%A0" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#ColorectalCancer @batllelab.bsky.social
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October 23, 2025 at 2:03 PM
A study published in #CancerDiscovery reveals why some colorectal cancers withstand pharmacological inhibition of #KRAS oncogene activity.
Read more here ➡️ https://bit.ly/3L0Cl2G
#CancerResearch olorectalCancer%C2%A0@batllelab.bsky.social%C2%A0" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#ColorectalCancer @batllelab.bsky.social
🧪
Read more here ➡️ https://bit.ly/3L0Cl2G
#CancerResearch olorectalCancer%C2%A0@batllelab.bsky.social%C2%A0" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#ColorectalCancer @batllelab.bsky.social
🧪
Reposted by Alberto Sogari
Lab Celebrations are in order. More news to come
October 17, 2025 at 7:22 AM
Lab Celebrations are in order. More news to come
Reposted by Alberto Sogari
Now online in Cancer Discovery @aacrjournals.bsky.social: The Molecular and Functional Landscape of Resistance to FOLFIRI Chemotherapy in Metastatic Colorectal Cancer - by Marco Avolio, Simonetta Leto, Andrea Bertotti, Livio Trusolino, and colleagues doi.org/10.1158/2159...
September 23, 2025 at 2:19 PM
Now online in Cancer Discovery @aacrjournals.bsky.social: The Molecular and Functional Landscape of Resistance to FOLFIRI Chemotherapy in Metastatic Colorectal Cancer - by Marco Avolio, Simonetta Leto, Andrea Bertotti, Livio Trusolino, and colleagues doi.org/10.1158/2159...
Reposted by Alberto Sogari
Who is joining us this week in Lyon for Persister Cells: from Bacteria to Cancer? We can’t wait to welcome you 👋
March 18, 2025 at 10:28 AM
Who is joining us this week in Lyon for Persister Cells: from Bacteria to Cancer? We can’t wait to welcome you 👋