Holidays!

Here we go again

🔥A new study led by @reiglab.bsky.social and @alegrecortes.bsky.social is now published on @cp-iscience.bsky.social 🙌
Researchers reveal how the brain organizes and directs its slowest activity: slow waves 🧠
More info 👇
in.umh-csic.es/en/articulos...

Stimulus-Dependent Dopamine Dynamics from LocusCoeruleus Axons https://www.biorxiv.org/content/10.1101/2025.09.15.676390v1

Preprint -
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...

Finding correlates of the same signal in different brain areas is not evidence against specialisation, it is evidence for interconnection.

When I flush my toilet, the level in the tank and the flow rate in the supply pipe become perfectly correlated. Yet these toilet areas have distinct functions.

Scientists in training should be taught the creative scientific process, to gain confidence in their self-efficacy for research and identity as a scientist, & also for greater work satisfaction and a better chance of remaining in science long-term. Join our community at www.night-science.org

I wrote a Comment on neurotheory, and now you can read it!

Some thoughts on where neurotheory has and has not taken root within the neuroscience community, how it has shaped those subfields, and where we theorists might look next for fresh adventures.

www.nature.com/articles/s41...

We should always take seriously where computational descriptions fail, as it tells us something about where the current boundaries of what we can describe in language lie

1. The philosophy of science sometimes gets an unearned reputation as a purely academic exercise that offers little by way of concrete tools for advancing research.

This is wrong.

And today, as we grapple with how AI is changing the nature of scientific activity, it's desperately wrong.

If you want to join us for a short stay and learn with us, that's a good opportunity. If you are interested, get in touch!

Lakatos on Popper isn't half bad

🚨 Upcoming postdoc openings 🚨

We will soon be hiring postdocs to work on neural data analysis & modelling in the context of a recently awarded ARIA grant aimed at "precision control" of neural population dynamics (w. collabs. across the UK)

Reach out if interested!

www.aria.org.uk/opportunity-...

🚨New paper🚨

Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.

Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW

We are looking for a Postdoc (up to 5 years) who wants to study neural mechanisms of spatial memory in honeybees.

This includes tetrode recordings in behaving honeybees.

Application Deadline is 1st of October 2025.

More details:
www.biozentrum.uni-wuerzburg.de/en/services/...

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world!

🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW

I'm very happy to see my first modelling work being published!
If you want to know more, take a look at the thread I wrote for the preprint version of the paper:
bsky.app/profile/aleg...

I'm excited to share my latest publication! 🚨
Global and local nature of cortical slow waves:
www.cell.com/iscience/ful...

In brief, we explored in silico how cortical slow waves are shaped by both external inputs and intrinsic properties of neuronal populations.

1
To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

Finally published:
“Explosive neural networks via higher-order interactions in curved statistical manifolds”
nature.com/articles/s4146…

Enhancing the capabilities of recurrent neural networks by deforming their geometry!

🚨New publication from the #DuguéLab on @erc.europa.eu funded research on #traveling_waves!
@sfnjournals.bsky.social

Work led by @kirstenpetras.bsky.social and @lgrabot.bsky.social

@upcite.bsky.social | @cnrs.fr

www.jneurosci.org/content/earl...

I believe at this time we can afford more nuance and precision than this. Most null results are uninformative because most experiments are uninformative because we use NHST to replace the scientific process. We can't keep avoiding the root problem forever. Also the focus on efficiency is jarring.

Hot take: Grid cells didn't evolve for spatial navigation, they evolved to play chess

Top-down and bottom-up neuroscience: overcoming the clash of research cultures rdcu.be/exi8N - yes, please!