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alexandrelaliberte.bsky.social
@alexandrelaliberte.bsky.social
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sparrerlab.bsky.social
Our story showing that HIV-1 Nef inhibits actin-mediated innate immune sensing is now out in @natcomms.nature.com. Awesome work by @alexandrelaliberte.bsky.social @caterinaprelli.bsky.social. Great collaboration with Frank Kirchhoff/Michaela Gack/Oliver Fackler. Thanks @dfg.de @bmftr!
rdcu.be/eTFJh
Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors
Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...
rdcu.be
December 12, 2025 at 3:15 PM
alexandrelaliberte.bsky.social
Excited to share our new paper and a new Nef function !

rdcu.be/eTFJh

Thanks to everyone involved!
@caterinaprelli.bsky.social
@sparrerlab.bsky.social

#hiv #Nef #innateimmunity #sensing #rlr #research
Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors
Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...
rdcu.be
December 12, 2025 at 11:29 AM
Reposted
caterinaprelli.bsky.social
Honored to receive the DZIF Doctoral Award of the @gesvirologie.bsky.social – It is a great motivation to keep going with my scientific career. Thank you @sparrerlab.bsky.social for the amazing words, I feel so grateful!
Big thanks also to Frank Kirchhoff and @alexandrelaliberte.bsky.social !
March 5, 2025 at 11:25 PM