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Allen Institute @alleninstitute.org · 18h

🚀 Please share with educators in your network with an appetite for open science!

Allen Institute @alleninstitute.org · 18h

🍳🍕 Free breakfast and lunch? Yes, please!

Undergraduate educators going to #CellBio2025 are invited to apply for our “Open Science & Authentic Research in Undergraduate Education” workshop happening on Dec. 5 in Philadelphia.

Apply by Oct 20: alleninstitute.org/events/open-...

Open Science & Authentic Research in Undergraduate Education: Pre-CellBio Workshop

Join the Open Science & Authentic Research in Undergraduate Education Workshop in Philadelphia, PA on December 5, 2025.

alleninstitute.org

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Allen Institute @alleninstitute.org · 19h

Caption for figure 4 above from study: "(A) Spatial distribution of Pvalb types that co-mingle. (B) Spatial distribution of L2/3 IT types that predominate in separate regions."

Allen Institute @alleninstitute.org · 19h

🧠📈 Do neurons of a feather flock together? Not quite.

New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.

📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...

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Allen Institute @alleninstitute.org · 21h

How can a silly-putty-like substance help us understand cancer cells?

Allen Distinguished Investigators @drlaurasanchez.bsky.social and @lydia-kisley.bsky.social are stretching the limits of #FrontierScience by developing a new way to look inside of cells.

@ucscscience.bsky.social

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Allen Institute @alleninstitute.org · 1d

This work was partly supported by NIH, Weill Neurohub, and Sandler Program for Breakthrough Biomedical Research.

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Allen Institute @alleninstitute.org · 1d

The potential of this tool goes beyond neuroscience. CellTransformer is tissue agnostic and can be used on other organ systems and tissues, including cancerous tissue.

Explore the code on GitHub: github.com/abbasilab/ce...

GitHub - abbasilab/celltransformer: Transformer based region discovery in spatial transcriptomics (but mostly MERFISH) datasets

Transformer based region discovery in spatial transcriptomics (but mostly MERFISH) datasets - abbasilab/celltransformer

github.com

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Allen Institute @alleninstitute.org · 1d

In a study out today in @natcomms.nature.com, the model successfully created a high-resolution atlas of the mouse brain with over 1,300 distinct regions and subregions, including new ways of grouping the brain’s cellular neighborhoods.

🗞️ www.nature.com/articles/s41...

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Allen Institute @alleninstitute.org · 1d

Introducing CellTransformer, a new AI tool developed with UCSF that makes it easier to explore massive neuroscience datasets and identify important subregions of the brain. 🧵

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Allen Institute @alleninstitute.org · 1d

Why do optical illusions work? The culprit may be a group of neurons in the visual cortex that help us fill in missing information.

@markjohnpost.bsky.social for @washingtonpost.com dives into the science and how it could help demystify visual hallucinations: www.washingtonpost.com/science/2025...

The origins of hallucinations are traced in specialized brain cells

Researchers used lasers to record and stimulate the activity of neurons in mice to learn how the brain processes and interprets optical illusions.

www.washingtonpost.com

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Allen Institute @alleninstitute.org · 2d

Congrats to Mary Brunkow from @isbscience.org on winning the Nobel Prize in Physiology or Medicine! Brunkow was honored with collaborators Ramsdell and Sakaguchi for their groundbreaking work on immune system regulation.

A proud moment for science and Seattle!

🔗 www.nytimes.com/2025/10/06/h...

Nobel Prize in Physiology or Medicine Is Awarded for Work on Immune Systems

www.nytimes.com

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Allen Institute @alleninstitute.org · 4d

Maybe the real anti-aging secret is the friends we make along the way? 🧠💕🧠

Explore the neurocognitive benefits of social connections with @dr-brein.bsky.social and the authors of a new review paper on "SuperAgers."

🧠📈 www.nytimes.com/2025/08/07/w...

The One Quality Most ‘Super-Agers’ Share

www.nytimes.com

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Allen Institute @alleninstitute.org · 4d

1M+ people live with SYNGAP1-related conditions, which can include severe seizures.

For the first time in mice models, gene therapy has reversed symptoms, even after onset. The breakthrough was achieved in collaboration with BioMarin.

🧠📈 Read the study: www.cell.com/molecular-th...

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Allen Institute @alleninstitute.org · 4d

Happy #FluorescenceFriday! Our #CellLineOfTheWeek is SMC (structural maintenance of chromosomes) protein 1A! 🧬🛠️

Our cell lines & plasmids are available for just the cost of shipping to reduce the barriers to scientific discovery.

📦 Dist. by @coriellinstitute.bsky.social & @addgene.bsky.social

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Reposted by Allen Institute

Science in Seattle @scienceinseattle.com · 25d

Neuroscientists are working to understand the mechanisms of addictive drug use and how to alleviate the debilitating withdrawal symptoms.

🎧 Check out the Lab Notes Podcast from the @alleninstitute.org to hear from researchers and social workers in the field: https://bit.ly/4n9qtJR

#Neuroscience

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Reposted by Allen Institute

Addgene @addgene.bsky.social · 22d

What is open science?
Watch this explainer video from @alleninstitute.org!

Allen Institute @alleninstitute.org · 23d

What is open science? 🤔

To celebrate #OpenScienceWeek, we're sharing why we give away our data, protocols, and resources to everyone.

Featuring our #openscience friends at @chanzuckerberg.bsky.social, NASA, @addgene.bsky.social, and NIH.

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Reposted by Allen Institute

Alan Boyle @b0yle.bsky.social · 22d

Scientists are learning how special brain cells play a role in detecting illusions - and such studies could eventually reveal how hallucinations arise, or point the way to better computer vision systems. www.geekwire.com/2025/laser-l... H/T @alleninstitute.org @natureportfolio.nature.com

Scientists shine a laser light on the brain cells that show us illusions

Neuroscientists are zeroing in on how special kinds of brain cells help us see things that aren't actually there.

www.geekwire.com

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Reposted by Allen Institute

Kindra Crick 🧩 @kindracrick.com · 19d

Just a few paintings of the 86 billion #neurons which help generate our every sensation & thought.

Untangled Series
India ink, colored pencil on hand dyed kozo paper

Created using the @alleninstitute.org Cell Type Database for references. Which is open to everyone.

#OpenScienceWeek 🧪 #SciArt

Allen Institute @alleninstitute.org · 20d

Open science is not just for researchers. Artist @kindracrick.com created these beautiful neuron portraits with inspiration from Ramón y Cajal's drawings and reference images from our Cell Types Database.

#OpenScienceWeek

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Reposted by Allen Institute

Sydney Floryanzia 👑 @neurochemequeen.bsky.social · 17d

Check out these and other tools from the @alleninstitute.org and follow the tags #OpenScienceWeek and #ScienceForAll to see other resources! #openscience

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Reposted by Allen Institute

Sydney Floryanzia 👑 @neurochemequeen.bsky.social · 17d

🧠 Celebrating #OpenScienceWeek, by highlighting my favorite (and my most used!) open science tools from the Allen Institute 🐭🧠🌐 @alleninstitute.org

#neuroskyence #neuroscience #brain #microscopy

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Reposted by Allen Institute

Addgene @addgene.bsky.social · 15d

Discover plasmids from the Allen Institute!
www.addgene.org/depositor-co...

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Reposted by Allen Institute

Science in Seattle @scienceinseattle.com · 7d

Scientists from the @alleninstitute.org and @benaroyaresearch.bsky.social discovered that #RheumatoidArthritis (RA) doesn’t start when the pain begins.

They found that people at risk for RA see dramatic immune system changes long before symptoms.

🗞️: https://bit.ly/4gJOcxO
🔬: https://bit.ly/4nU1oT9

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Allen Institute @alleninstitute.org · 11d

How do sex hormones influence organ development?

ADIs Mijo Simunovic, @elhamazizi.bsky.social, and José L. McFaline-Figueroa are searching for the answers by making an in-vitro platform that combines stem cells, genome editing, and AI. #FrontierScience

🔗 alleninstitute.org/division/fro...

Sex hormone morphogenesis: a new frontier in studying organ development

In this project, researchers will develop an in vitro platform that combines stem cell models of human development, high-throughput genome editing at the single cell level, and novel machine learning ...

alleninstitute.org

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Allen Institute @alleninstitute.org · 11d

Happy #FluorescenceFriday! Our #CellLineOfTheWeek is Histone H2B! 🧬

Our stem cell lines and plasmids are available for just the cost of shipping to reduce the barriers to scientific discovery.

📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social

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Allen Institute @alleninstitute.org · 12d

This research was made supported through The Shanahan Foundation Fellowship at the Interface of Data and Neuroscience.

Get to know Ryan and read his experience as a Shanahan Fellow: alleninstitute.org/news/from-mi...

From Midwest to Mentorship: A Scientist’s Full-Circle Journey in Neuroscience

At the Allen Institute, Raut took full advantage of the opportunities and independence provided by the three-year-long Shanahan Foundation Fellowship to better understand the mysteries of the brain.

alleninstitute.org

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