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Reposted by Ando Lab

Nozomi Ando @nozomi-ando.bsky.social · 14d

Fall beamtime begins! Here is Sarah @andolab.bsky.social ! 😎⚡️

@diffuseproject.bsky.social

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Ando Lab @andolab.bsky.social · 21d

We are elated to *finally* announce that our PI @nozomi-ando.bsky.social has been selected as a 2025 Schmidt Polymath!

Combining geology, evolutionary biology, and biochemistry, we will take our understanding of how life evolved with our planet to the next level!
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www.linkedin.com/posts/schmid...

#schmidtpolymaths | Schmidt Sciences

Announcing the 2025 Schmidt Polymaths: Eight exceptional scientists who embody the future of interdisciplinary research. Selected from universities worldwide, each Schmidt Polymath receives up to $2....

www.linkedin.com

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Reposted by Ando Lab

Nozomi Ando @nozomi-ando.bsky.social · 25d

Marcus @andolab.bsky.social getting ready for fall beamtime for the @diffuseproject.bsky.social 🔥

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Reposted by Ando Lab

Seemay Chou @seemaychou.bsky.social · Aug 12

What’s the next PDB? Maybe it’s …the PDB.

We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇

www.diffuse.science

The Diffuse Project

www.diffuse.science

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Ando Lab @andolab.bsky.social · Aug 13

Thanks to generous funding from the Astera Institute and collaborators across the country, we are equipped to tackle a great challenge facing structural biologists today!

Keep up with the Diffuse Project on the official website and follow @diffuseproject.bsky.social

diffuse.science

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The Diffuse Project

diffuse.science

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Ando Lab @andolab.bsky.social · Aug 13

We are proud to announce our newest adventure!

Introducing the Diffuse Project, a community-driven effort to predict protein dynamics using the subtle diffuse scattering signal from protein crystals. This collaboration marks a new era for the Ando lab!

as.cornell.edu/news/philant...

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Philanthropic support accelerates infrastructure for the future of structural biology

A new $5 million initiative, funded by the Astera Institute with experimental work conducted at the Cornell High Energy Synchrotron Source, aims to make diffuse scattering accessible to the public and...

as.cornell.edu

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Reposted by Ando Lab

Nozomi Ando @nozomi-ando.bsky.social · Jul 3

Happy 11th birthday to @andolab.bsky.social ! 🎂 🥳 Also happy to share that I'm a full prof as of July 1 -- thanks to my awesome group, past and present.

We're now looking to grow the team! Looking for someone with amazing protein skills and postdocs excited about evolutionary questions!

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Ando Lab @andolab.bsky.social · Mar 21

After CSHL, Haoyue also visited @chloamphenicol.bsky.social, currently at Rutgers IQB, to talk more #cryoEM ❄️✌️

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Reposted by Ando Lab

Nozomi Ando @nozomi-ando.bsky.social · Mar 20

Woo! It’s Haoyue and her teammates! 🎉 Looks like they had a fabulous time!

Lander Lab @landerlab.bsky.social · Mar 19

Congrats to Group 1, winners of the 2025 CSHL #CryoEM course! They reconstructed a 1.9 A structure from 100 images, the built and refined an outstanding atomic model with great validation metrics. They are the recipients of the new Cryo Champion Chalice, adorned with $2,467 worth of used autogrids!

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Ando Lab @andolab.bsky.social · Mar 12

Congratulations to everyone who contributed to this amazing work! 🎉
If you want to see how enzymes move during catalytic turnover, check out our latest paper! 🧪🧶

Nozomi Ando @nozomi-ando.bsky.social · Mar 12

Some happy news from @andolab.bsky.social !! 😀🥳

Ever wonder how protein motions regulate enzyme turnover? Check out this paper by Darren (Da) Xu, et al. that was published today: rdcu.be/edf2A

Conformational landscapes of a class I ribonucleotide reductase complex during turnover reveal intrinsic dynamics and asymmetry

Nature Communications - Structural dynamics play an essential role in enzymatic catalysis. Here, the authors use cryo-EM to reveal the conformational landscapes of a class I ribonucleotide...

rdcu.be

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Reposted by Ando Lab

Nozomi Ando @nozomi-ando.bsky.social · Feb 12

Cornell Chemistry welcomed prospective graduate students with karaoke night! If you've never heard our department chair Tristan Lambert rap, you are missing out! 🎵🎤 #SingingChemists

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Ando Lab @andolab.bsky.social · Jan 14

Congratulations! This is a monumental review 🎉

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Reposted by Ando Lab

Nozomi Ando @nozomi-ando.bsky.social · Dec 24

Happy Holidays from @andolab.bsky.social ! Wishing you all a wonderful 2025 🥳

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Ando Lab @andolab.bsky.social · Dec 21

Happy holidays! This year the Ando Lab celebrates three new PhDs and three new PhD candidates! Congratulations! 🧪

And visit our new lab website at ando.chem.cornell.edu

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Ando Lab @andolab.bsky.social · Nov 26

Thank you so much!

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Ando Lab @andolab.bsky.social · Nov 26

Finally, we are a lab that loves good food, good music, and stable beams. We hope to create a great network of structural biologists, biophysicists, and chemists on Bluesky! 🧪🦋 5/5

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Ando Lab @andolab.bsky.social · Nov 26

Here is our most recent work on a textbook example of protein allostery, a conclusion to a story 70 years in the making! 🧬🧶 4/5 www.biorxiv.org/content/10.1...

Mechanism of Nucleotide-Dependent Allosteric Regulation in Escherichia coli Aspartate Transcarbamoylase

Discovered nearly 70 years ago, the allosteric regulation of Escherichia coli aspartate transcarbamoylase (ATCase) is discussed in every biochemistry textbook. ATCase catalyzes the first step in pyrim...

www.biorxiv.org

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Ando Lab @andolab.bsky.social · Nov 26

We also aim to capture correlated motions of proteins using #synchrotron x-ray diffuse scattering. ⚛️ 3/5 www.sciencedirect.com/science/arti...

Introduction to diffuse scattering and data collection

A long-standing goal in X-ray crystallography has been to extract information about the collective motions of proteins from diffuse scattering: the we…

www.sciencedirect.com

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Ando Lab @andolab.bsky.social · Nov 26

We are interested in the #dynamics and #evolution of enzyme allostery and catalysis. We use #SAXS, #cryoEM, crystallography, and bioinformatics. We apply this to complex enzymes. 2/5 www.biorxiv.org/content/10.1...

Conformational Landscapes of a Class I Ribonucleotide Reductase Complex during Turnover Reveal Intrinsic Dynamics and Asymmetry

Understanding the structural dynamics associated with enzymatic catalysis has been a long-standing goal of structural biology. A wide range of motions, from small side-chain fluctuations to large doma...

www.biorxiv.org

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Ando Lab @andolab.bsky.social · Nov 26

Hello Bluesky! 🧪 We are the students in the Ando Lab at Cornell. We study the structure and dynamics of enzymes using biochemical and biophysical tools such as x-rays and cryoEM. 🧬🧶 Here is a brief introduction to our recent work! ⬇️ 1/5

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