...from University of Reading, Technical University of Denmark, and Universidad de Costa Rica. Also, a big thanks to our funders, Villum Foundation, European Research Council, Wellcome, Medical Research Council, Marie Skłodowska-Curie Actions, and to Trends in Biotechnology for publishing the work!

Thanks to my fantastic collaborators, José R. Almeida, Christoffer Vinther Sørensen, Soheil Gilabadi, Jarred Williams, Husain Bin Haidar, Mark von Bülow Møiniche,
Melisa Benard Valle, Esperanza Rivera de Torre, David Schultz, Andrew Urquhart, Bruno Lomonte, Ketan Patel, and Sakthivel Vaiyapuri...

We use very small doses. Enough to activate the immune system, but not so much that they harm the animals.

This opens a path to acid-switched / sweeping antibodies that recycle and neutralise multiple antigens without changing the paratope.

#sweeping #toxins #mAbs #acidswitching

Thanks to all co-authors & funders for making this possible!

Also a big thanks to our generous funders, Villum Fonden, European Research Council (ERC), Wellcome Trust, and Consejo Nacional de Ciencia y Tecnología!

Johannes R. Loeffler, Andrew B. Ward, Kim Boddum, Jens Preben Morth, and Esperanza Rivera de Torre from @dtu.dk, Universidad Nacional Autónoma de México, Sophion Bioscience, and Scripps Research.

Thanks to great co-authors, including Anna Damsbo Jensen, Nick J. Burlet, Monica L. Fernández-Quintero, Melisa Benard-Valle, Max Overath, Alid Guadarrama-Martínez, Anneline Vlamynck, Ida Bisbo, César Noé Villalobos Carrizosa, Tulika Laprade, Alejandro Alagon...

While the work has immediate implications for snakebite envenoming, the methodologies developed here are generally useful for developing broadly-neutralising antibodies.