andrzejdziembowski.bsky.social
@andrzejdziembowski.bsky.social
Reposted
Come discuss recent breakthroughs in RNA biology, from molecules to organisms, at the EMBO | EMBL Symposium 'The complex life of RNA'! 👉 s.embl.org/ees26-12-bl

Submit your abstract by 7 July and present your research at #EESRNA 🥼
November 14, 2025 at 4:33 PM
Reposted
🎓 PhD at IIMCB – Where Ambition Meets Discovery!

Check 14 positions in neuroscience, virology, RNA & cell biology. Join our vibrant, international research community in Warsaw! 🤝

🗓️ Apply: May 19 – June 1

🔗 tinyurl.com/phd-iimcb-2025

#PhD #Warsaw4PhD #PhDlife #PhDOpportunities
May 20, 2025 at 2:48 PM
Reposted
Scientists from the IIMCB described a new mechanism that improves the efficiency of mRNA-based therapies. The research findings will facilitate the development of novel therapeutics against cancers and infectious diseases.

#NaturePublication #mRNA #RNAResearch #IIMCB #FunduszeUE
April 29, 2025 at 8:33 AM
Reposted
#mRNA #vaccine stability and efficacy depends on its #polyA tail and is boosted by re-adenylation in #macrophages by my favourite enzyme TENT5A - in @nature.com by @pakraw.bsky.social and Seweryn Mroczek, Lab of RNA Biology - ERA Chairs Group @iimcb.bsky.social led by @andrzejdziembowski.bsky.social
🎉 Incredibly proud to share my first-author paper in
@nature.com! Heartfelt thanks to my mentor @andrzejdziembowski.bsky.social and the brilliant team at DziembowskiLab at @iimcb.bsky.social. More details in the 🧵below ⬇️
April 17, 2025 at 7:41 PM
Happy to share with you our new @nature.com story about the crucial role of TENT5A-mediated re-adenylation of mRNA COVID-19 vaccines in boosting their efficacy. We also show how important macrophages are in producing the antigen following vaccination. www.nature.com/articles/s41...
April 17, 2025 at 7:00 AM
Reposted
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines @nature.com @andrzejdziembowski.bsky.social @pakraw.bsky.social
www.nature.com/articles/s41...
April 16, 2025 at 4:49 PM
Reposted
If you want to do single-cell RNA-seq on your favourite bacterium, here‘s our detailed Nature Protocol for microbial MATQ-seq. It profiles up to 600 genes in a single bacterial cell!

www.nature.com/articles/s41...
Transcriptomic profiling of individual bacteria by MATQ-seq - Nature Protocols
Bacterial single-cell sequencing via MATQ-seq combines index sorting, random priming and rRNA depletion, and offers high cell retention and transcript capture rates, making it ideal for experiments wi...
www.nature.com
April 9, 2025 at 9:15 AM
Reposted
My first (and probably the last), first-author @nature.com paper formally accepted. Huge effort of all people involved, mostly from the Laboratory of RNA Biology, IIMCB in Warsaw (all authors are from Polish institutions!). More details when the manuscript will be in press.
February 28, 2025 at 2:23 PM
Reposted
In vitro transcription (IVT) is a technology that facilitated the production of mRNA therapeutics and drove numerous breakthroughs in RNA biology. Our new study uncovers unexpected insights into the immunogenicity of in IVT RNAs. #RNA #IVT #Immunity

academic.oup.com/nar/advance-...
5′ terminal nucleotide determines the immunogenicity of IVT RNAs
Abstract. In vitro transcription (IVT) is a technology of vital importance that facilitated the production of mRNA therapeutics and drove numerous breakthr
academic.oup.com
December 20, 2024 at 6:52 PM
Reposted
TRIM25 takes a centre stage! Right in the context of its RNA-binding role. Exogenous RNA surveillance by proton-sensing TRIM25 | Science www.science.org/doi/abs/10.1...
Exogenous RNA surveillance by proton-sensing TRIM25
Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens...
www.science.org
April 6, 2025 at 12:55 PM
Reposted
Dear Polish and European RNA Researchers,
Don’t forget to register for the 2nd Polish RNA Biology Meeting in Poznan, June 24-27! 🧬✨ It’s gonna be an incredible event with an AMAZING lineup of keynote speakers already confirmed! 🎉#RNA

👉 Register here: 2ndrna.web.amu.edu.pl
Home - 2nd Polish RNA Meeting
2ndrna.web.amu.edu.pl
February 25, 2025 at 1:31 PM