Anna Ralser
@annaralser.bsky.social
Postdoc in Pelka Lab @ UCSF-Gladstone | Cancer Immunology | Immunotherapy | Spatial Profiling
Reposted by Anna Ralser
1/ New preprint! 🍳
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
March 18, 2025 at 2:48 PM
1/ New preprint! 🍳
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
@elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins!
doi.org/10.1101/2025...
Reposted by Anna Ralser
Nature research paper: Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted
https://go.nature.com/3PJXHQP
https://go.nature.com/3PJXHQP
Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted - Nature
Profiling of the location and transcriptome of tissue-resident memory CD8 T cell formation at single-transcript resolution finds regionalized signalling as the basis of immune diversity in the intestine and provides a conceptual framework for the study of tissue immune networks.
go.nature.com
January 23, 2025 at 7:12 AM
Nature research paper: Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted
https://go.nature.com/3PJXHQP
https://go.nature.com/3PJXHQP
Wow - this is so cool! And an amazing 🧵
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 12, 2024 at 1:00 AM
Wow - this is so cool! And an amazing 🧵
Awesome showcase highlighting the power of spatial technologies 🧬📍
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 22, 2024 at 5:35 PM
Awesome showcase highlighting the power of spatial technologies 🧬📍