anniemarchildon.bsky.social
@anniemarchildon.bsky.social
PhD student in Tajie Harris' lab @ the University of Virginia
Interested in glia and neuroimmunology⭐️
Reposted
I've been really hoping to see more manuscript threads here on 🦋, so here comes one!!! This is brand new work from the lab that took us in very unexpected directions and to exciting findings led by the amazing @emily-hill.bsky.social. Preprint here www.biorxiv.org/content/10.1...
and 🧵below:
June 30, 2025 at 6:26 PM
Reposted
STING deletion protects against amyloid β–induced Alzheimer's disease pathogenesis - Thanos - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
STING deletion protects against amyloid β–induced Alzheimer's disease pathogenesis
INTRODUCTION While immune dysfunction has been increasingly linked to Alzheimer's disease (AD) progression, many major innate immune signaling molecules have yet to be explored in AD pathogenesis us...
alz-journals.onlinelibrary.wiley.com
May 24, 2025 at 2:03 PM
Reposted
Happy to share that our work "Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease" is out now @cp-immunity.bsky.social! ➡️ www.cell.com/immunity/ful...
Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease
Why microglia stop reducing amyloid deposits from Alzheimer’s disease (AD) brains is unknown. Prakash, Manchanda, et al. show that microglia increase their lipid droplets and lose their phagocytic cap...
www.cell.com
May 19, 2025 at 6:14 PM
Reposted
Excited to share our review on astrocyte aging, out today! Hopefully the only Friday surprises this week are Liddelow lab publications! 🧪 #neuroskyence @liddelowsa.bsky.social
Mechanisms of astrocyte aging in reactivity and disease - Molecular Neurodegeneration
Normal aging alters brain functions and phenotypes. However, it is not well understood how astrocytes are impacted by aging, nor how they contribute to neuronal dysfunction and disease risk as organis...
molecularneurodegeneration.biomedcentral.com
February 21, 2025 at 12:08 PM
Reposted
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February 6, 2025 at 6:45 PM