Arnaud Le Rouzic
@arnaudlerouzic.bsky.social
110 followers 120 following 8 posts
CNRS researcher (IDEEV, Université Paris-Saclay, France). Evolutionary genetics, theoretical quantitative genetics, systems biology. Associate editor at J. Evol. Biol. Bridge to my Mastodon account: @arnaudlerouzic.fediscience.org.ap.brid.gy
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arnaudlerouzic.bsky.social
Come and join our team! A 2-year postdoc position is available in our "Genome Evolution" department at Univ Paris Saclay. We want to play with phylogenetic models accounting for horizontal transfers of transposable elements. Application& details on the official portal: emploi.cnrs.fr/Offres/CDD/U...
Object: Postdoc Position 

Building a phylogenetic model for horizontal transfers of transposable elements 

A postdoctoral position (24 months) is available to work at EGCE (Gif-sur-Yvette, France, CNRS / Université Paris-Saclay) from January 2026. 

Transposable elements (TEs) are repetitive DNA sequences capable of promoting their own mobility. They are widespread across the tree of life and often represent a substantial fraction of eukaryotic genomes. Beyond their ability to invade genomes, TEs are frequently reported to undergo horizontal transfer, enabling their colonization of new hosts. However, understanding and predicting how horizontal transfers shape the distribution of TEs among species is far from straightforward. In particular, estimates of transfer rates based on documented cases are both biased and approximate, since transfers occurring close to speciation events are virtually undetectable. This project aims to develop explicit phylogenetic models of TE evolution that incorporate horizontal transfers, and to use these models to obtain statistical estimates of key evolutionary dynamics of TE families across species (e.g., horizontal transfer and extinction rates). The postdoctoral project will focus on exploring the impact of horizontal transfers on the distribution of TE presence/absence among related species, using statistical and/or computational approaches. Context

The position will be part of a 4-year collaborative project funded by the French National Agency (ANR). The research consortium gathers two departments (from Paris-Saclay university and from Université Lyon 1), and involves 7 Pls and 5 postdocs and PhD students devoted to distinct workpackages of the project. The postdoc will be based at EGCE, which is part of the Institute for Ecology and Evolution (IDEEV). The institute offers an exciting and active scientific life, it is located on the new research campus of Paris-Saclay, 35 km south of Paris. 

Relevant references

Gilbert C et al. 2018. Horizontal acquisition of transposable elements and viral sequences: patterns and consequences. Cur. Opin. Genet. Dev. 49:15-24.

Le Rouzic A et al. 2013. Reconstructing the Evolutionary History of Transposable Elements. Genome Biol. Evol. 5:77-86.

Wallau GL et al. 2016. VHICA, a New Method to Discriminate between Vertical and Horizontal Transposon Transfer: Application to the Mariner Family within Drosophila. Mol Biol Evol 33:1094-1109.

Profile

We are looking for a motivated early career theoretical biologist, with a PhD in theoretical evolutionary biology. Skills in statistics, programming, bio-informatics, and phylogenetic models will be appreciated.

Application

Formal applications (CV and cover letter) have to be deposited on the CNRS job portal https://emploi.cnrs.fr/Offres/CDD/UMR9191-ARNLER-006/Default.aspx?lang=EN.
arnaudlerouzic.bsky.social
It is probably worth checking whether this is even compatible with their own copyright transfer agreement. It would be equivalent to e.g. proposing alternative definitions of their own in the margins of published papers, alternative wording, etc. without the author's consent.
Reposted by Arnaud Le Rouzic
arnaudlerouzic.bsky.social
To be totally transparent, one needs to consider the hidden cost for the European scientific community to write ~ 4000 40+page grants. Assuming a couple of months of work per grant + many days spent on evaluating them, this is > 1000 years or research from experts lost in this bureaucratic process.
Reposted by Arnaud Le Rouzic
stuwest.bsky.social
Mike Ritchie emphasising the huge importance of supporting society journals like JEB in his ESEB presidential address, Barcelona. @eseb.bsky.social @eseb2025.bsky.social
Reposted by Arnaud Le Rouzic
aveneziano.bsky.social
Ethical scientific journals and where to find them....here is DAFNEE, a #database of non-profit journals in #Ecology and #Evolution #EvoBio, to choose an ethical place where to publish your next articles! (1/2)

dafnee.isem-evolution.fr

🧪 #science
DAFNEE, a Database of Academia Friendly jourNals in Ecology and Evolution
dafnee.isem-evolution.fr
Reposted by Arnaud Le Rouzic
lmchev.bsky.social
Our paper on evolution of plasticity and character displacement in a fluctuating environment is now published as early view in Evolution. Check it out if you're interested in eco-evolutionary dynamics, coevolution... and plasticity of course!
academic.oup.com/evolut/advan...
Evolution of plasticity and character displacement in a fluctuating environment
academic.oup.com
Reposted by Arnaud Le Rouzic
pdvsky.bsky.social
Very glad to see the second chapter of my PhD published in JEB and feel honored that it has been picked as this month's issue "Editor's choice" and cover image! It's been a long and important team effort leading up to these results!
jevbio.bsky.social
The May issue of JEB is now online! Read it here:

academic.oup.com/jeb/issue/38/5

📸 Coenonympha arcania: part of an intriguing species complex in which two hybrid species have inherited most of their genome from one parent species but prefer mating with the other! Photo Credit - Riccardo Poloni
Volume 38 Issue 5 | Journal of Evolutionary Biology | Oxford Academic
Journal of Evolutionary Biology
academic.oup.com
arnaudlerouzic.bsky.social
It is frequently believed that cis-regulatory mutations in gene promoters have smaller and less pleiotropic effects than trans-acting mutations in the coding sequence. We could show that this pattern is not a universal truth, as it can only be observed in scale-free regulatory networks.
arnaudlerouzic.bsky.social
Based on simulations, we show that the size and pleiotropy of mutations affecting gene expression heavily depend on the structure of the underlying gene network.
A figure extracted from the scientific paper (https://doi.org/10.1093/evolut/qpaf068). The effect of mutations on fitness depends on the mutation size and the mutation type (Regulatory or Coding mutations). Yet, the network topology (Highly connected, Random, or Scale-free) is a game changer, and conditions which kind of mutation matters the most for fitness.
arnaudlerouzic.bsky.social
Very happy to announce the publication of our latest work by my former student Sylvain Pouzet in @journal-evo.bsky.social: "Gene network topology drives the mutational landscape of gene expression".

doi.org/10.1093/evol...

#GeneRegulatoryNetworks
#PopulationGenetics
#EvolutionarySystemsBiology
A theoretical gene regulatory network, featuring 10 genes connected randomly.
arnaudlerouzic.bsky.social
Job ad: we are looking for a IT/bioinformatician for 12 months, located in the Paris-Saclay campus: emploi.cnrs.fr/Offres/CDD/U...

In French: nous cherchons un ingénieur en bio-informatique (CDD 12 mois) pour de la maintenance serveurs, formation, et assistance utilisateurs.
Portail Emploi CNRS - Offre d'emploi - Ingénieur d’études en bio-informatique (H/F)
emploi.cnrs.fr
Reposted by Arnaud Le Rouzic
jevbio.bsky.social
Why publish in JEB?

✅ Society-owned and not-for-profit model
✅ Dedicated submission support - in-house Managing Editor
✅ Range of article types
✅ Modern Open Science policies - our own Data Editor
✅ Large editorial board with wide-range of expertise

#societyjournal @eseb.bsky.social
arnaudlerouzic.bsky.social
Several thousand people today at #standupforscience2025 in Paris.
Reposted by Arnaud Le Rouzic
vakirlis.bsky.social
Happy to announce that I have joined the editorial board of the Journal of Evolutionary Biology @jevbio.bsky.social as an Associate Editor. Hope to contribute as much as I can to the journal and to @eseb.bsky.social .
Reposted by Arnaud Le Rouzic
yruama.bsky.social
SpringerNature keeps on creating new outlet after new outlet... Seems like nothing can stop them.
Just like that joke of a guy putting coins into the soda vending machine: "So long as I'm winning, I'm playing"...

But who pays? We researchers are the fools and we seem to like it.
natureportfolio.nature.com
Introducing Nature Reviews Biodiversity! This Review explores the relationship between emerging infectious diseases and biodiversity loss, and how both are connected to global environmental changes in the Anthropocene. https://go.nature.com/42fzUQk 🧪
This is figure 2, which shows two perspectives on land use as a driver of biodiversity loss and disease emergence.