Antiretroviral Therapy for Multiple Sclerosis
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Antiretroviral Therapy for Multiple Sclerosis
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Rationale for Antiretroviral Therapy for Treatment of Multiple Sclerosis art4ms.com #multiplesclerosis #ms #ebv
This indicates that the standard dose of TAF may be lower than optimal for EBV, as the EC90 is a typical therapeutic target. This data comes from an in vitro assay and the optimal dose needs to be determined in humans.
January 20, 2026 at 11:56 PM
TAF is a newer generation prodrug designed for better tissue targeting, allowing for lower doses. A 25mg dose of TAF leads to higher tenofovir concentrations in lymphocytes compared to a 300mg dose of TDF.
January 20, 2026 at 10:02 PM