@atorbo.bsky.social
Reposted
Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer https://www.biorxiv.org/content/10.1101/2024.03.18.584896v1
Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer https://www.biorxiv.org/content/10.1101/2024.03.18.584896v1
Adoptive transfer of regulatory T cells (Tregs) is a promising strategy to combat immunopathologies
www.biorxiv.org
March 19, 2024 at 2:15 AM
Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer https://www.biorxiv.org/content/10.1101/2024.03.18.584896v1
Reposted
Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific NK cells @sahakris.bsky.social
www.cell.com/molecular-th...
www.cell.com/molecular-th...
Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific natural killer cells
Saha and colleagues report an improved method to genetically engineer human primary
natural killer (NK) cells using a virus-free CRISPR strategy, yielding high editing
outcomes with minimal off-target...
www.cell.com
January 19, 2025 at 3:30 AM
Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific NK cells @sahakris.bsky.social
www.cell.com/molecular-th...
www.cell.com/molecular-th...