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auditorynerves.bsky.social
Dan Jagger
@auditorynerves.bsky.social
5.9K followers 3K following 1.9K posts
Professor of Cell Physiology, Ear Institute, University College London Research interests: ion channels, hearing/deafness, cilia, rare diseases, neurons, glia www.ucl.ac.uk/ear/research/jaggerlab Insta: @jaggerlab
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · Oct 12
We've been looking at historic human inner ear sections - this from the late 1920s.

The histology stain used is written on, in this case "Kulchitsky Weigert Pal". With no training in the area I've looked up what this is, & as a consequence who Kulchitsky was.

Strap in, it's quite a story. 🧪🔬
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Glass slide with stained tissue
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 1d
Open access link to new study in Nature Communications:

Sex-stratified genome-wide association meta-analysis of major depressive disorder.

🧪🧠♀️
www.nature.com/articles/s41...
Sex-stratified genome-wide association meta-analysis of major depressive disorder - Nature Communications
Sex differences are well established in the prevalence and symptoms of depression. Here, the authors identify a novel X chromosome variant, greater genetic risk, and stronger links to metabolic traits in females, highlighting the importance of sex-aware approaches.
www.nature.com
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 1d
Women carry a higher genetic risk of depression, new study says.

Researchers in Australia find 16 genetic variants linked to depression in women but only eight in men.

🧪🧠♀️ #neuroskyence

www.theguardian.com/science/2025...
Women carry a higher genetic risk of depression, new study says
Researchers in Australia find 16 genetic variants linked to depression in women but only eight in men
www.theguardian.com
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 2d
Nobel Prize in Physiology or Medicine 2025 awarded for discoveries that explain how the immune system attacks hostile infections, but not the body's own cells.

The prize is shared by Japan's Shimon Sakaguchi & US researchers Mary Brunkow & Fred Ramsdell. 🧪

www.bbc.co.uk/news/article...
Nobel Prize for immune system stops destructive rampage
The prize-winning work explains how the immune system attacks hostile infections, but not the body's own cells.
www.bbc.co.uk
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 3d
I'm guessing they're not about to re-enact a Civil War battle?

www.thekingsarmy.org.uk/8203who-we-a...
​Who we are and what we do
​ Who we are and what we do.
www.thekingsarmy.org.uk
auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 4d
Open access link to new study in Nature Communications:

A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study.

🧪💉🐘
www.nature.com/articles/s41...
A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study - Nature Communications
Elephant endotheliotropic herpesvirus (EEHV) haemorrhagic disease is a major threat for juvenile Asian elephants. This study reports a proof-of-concept trial that evaluates the safety and immunogenicity of a vaccine against EEHV.
www.nature.com
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 4d
Researchers have developed a new vaccine to prevent a deadly virus that affects young elephants.

It targets elephant endotheliotropic herpesvirus (EEHV), which is currently a leading cause of death in young Asian elephants.

🧪💉🐘
www.bbc.com/news/article...
Vaccine breakthrough for deadly elephant virus
A vaccine against a deadly disease that affects young elephants is shown to be effective in a world-first trial.
www.bbc.com
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Reposted by Dan Jagger
mathcancer.bsky.social
Paul Macklin @mathcancer.bsky.social · 5d
We're hiring several tenure-track biomedical engineering faculty (at open rank) at IU Bloomington! Come join me in a very multidisciplinary, forward-focused culture that integrates cutting-edge engineering, computing, and artificial intelligence. 🧪

indiana.peopleadmin.com/postings/30517
Multiple, Open Rank, Tenure-Track/Tenured Faculty Positions in Biomedical Engineering
Indiana University Bloomington (IUB) is engaged in a multi-year initiative to increase the breadth and scope of its faculty in biomedical engineering. We are inviting applications for multiple tenure-...
indiana.peopleadmin.com
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 4d
I see King Herod finally got his comeuppance.
Diddy? Yes he did.
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 5d
😂
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 5d
Sure, sure.
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 5d
I'm only here for the centrist Dad chat.
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 5d
Very needy.
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 5d
I never liked synapses.
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 5d
🧪
auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 6d
😢
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 6d
Will nobody consider the feelings of the billionaires?
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Reposted by Dan Jagger
notyourrealdad.bsky.social
Nat ⁷ @notyourrealdad.bsky.social · 6d
“The results of this study indicate that earlier- and later-diagnosed autism are associated with different developmental trajectories, and are only moderately genetically correlated with each other.”

As a woman who wasn’t diagnosed until her late 30’s, I love seeing this kind of research.
auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 7d
Open access link to new study in Nature:

Polygenic and developmental profiles of autism differ by age at diagnosis.

🧪🧠 #medsky #neuroskyence
www.nature.com/articles/s41...
Polygenic and developmental profiles of autism differ by age at diagnosis - Nature
A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.
www.nature.com
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 6d
If MDPI have a dodgy reputation, even only in part, they need to clean up their act across the board.

Review only for journals you submit work to, is one approach I've used. Do 2-3 reviews per 1 submitted manuscript.
auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 6d
More on the Southern Resident orca/killer whale (Orcinus orca) here:
🧪🐋
www.fisheries.noaa.gov/species/kill...
Killer Whale
The killer whale is the largest member of the dolphin family. The population of Southern Resident killer whales in the Pacific Northwest is one of the most critically endangered marine mammals. Learn ...
www.fisheries.noaa.gov
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 6d
Dogs & drones: how scientists are saving Washington’s endangered orcas.

Experts are finding new & more humane ways to protect the last 74 southern resident killer whales.

🧪🐋🐶
www.theguardian.com/environment/...
Dogs and drones: how scientists are saving Washington’s endangered orcas
Experts are finding new and more humane ways to protect the last 74 southern resident killer whales
www.theguardian.com
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 7d
Yes! 😂
auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 7d
Just between you & me, Nature are money-grabbing slags. It's the authors or their employers/funders/university that pays for the open access. Rant over 🙂
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 7d
Monkeys with robot arms. What more could they want? 🐒🤖
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auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 7d
Open access link to new study in Nature:

Polygenic and developmental profiles of autism differ by age at diagnosis.

🧪🧠 #medsky #neuroskyence
www.nature.com/articles/s41...
Polygenic and developmental profiles of autism differ by age at diagnosis - Nature
A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.
www.nature.com
2 8 26
auditorynerves.bsky.social
Dan Jagger @auditorynerves.bsky.social · 7d
Autism should not be seen as single condition with one cause, say scientists.

Those diagnosed as small children typically have distinct genetic profile from those diagnosed later.

🧪🧠 #medsky #neuroskyence

www.theguardian.com/society/2025...
Autism should not be seen as single condition with one cause, say scientists
Those diagnosed as small children typically have distinct genetic profile from those diagnosed later, study finds
www.theguardian.com
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