Alexander Ying
@awy2110.bsky.social
Excited to see the complete publication out for some incredible work led by the incomparable Sid Jain and Cigall Kadoch @ckadoch.bsky.social!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform
Mammalian SWI/SNF chromatin remodeling complexes modulate DNA accessibility and gene expression; however, their genomic targeting mechanisms remain incompletely understood. Here, we identify SWIFT (SW...
www.science.org
January 1, 2026 at 8:00 PM
Excited to see the complete publication out for some incredible work led by the incomparable Sid Jain and Cigall Kadoch @ckadoch.bsky.social!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Alexander Ying
🧬 @science.org A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform | Science www.science.org/doi/10.1126/... @ckadoch.bsky.social @danafarber.bsky.social @harvardmed.bsky.social @broadinstitute.org @hhmi-science.bsky.social 🔬 #chromatin #transcription #cancer 🧫
A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform
Mammalian SWI/SNF chromatin remodeling complexes modulate DNA accessibility and gene expression; however, their genomic targeting mechanisms remain incompletely understood. Here, we identify SWIFT (SW...
www.science.org
January 1, 2026 at 7:53 PM
🧬 @science.org A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform | Science www.science.org/doi/10.1126/... @ckadoch.bsky.social @danafarber.bsky.social @harvardmed.bsky.social @broadinstitute.org @hhmi-science.bsky.social 🔬 #chromatin #transcription #cancer 🧫
Reposted by Alexander Ying
@ckadoch.bsky.social and I are excited to welcome you to Geneva for the 2026 Keystone Symposium on Epigenetics and Gene Regulation in Health and Disease — short talk and poster slots are still open. Don’t miss the deadlines.
Video: youtu.be/sLfyuQuH8F0
Video: youtu.be/sLfyuQuH8F0
KSQA: Dr Karim-Jean Armache / Dr. Cigall Kadoch (Epigenetics and Gene Regulation)
YouTube video by KeystoneSymposia
youtu.be
November 3, 2025 at 2:43 PM
@ckadoch.bsky.social and I are excited to welcome you to Geneva for the 2026 Keystone Symposium on Epigenetics and Gene Regulation in Health and Disease — short talk and poster slots are still open. Don’t miss the deadlines.
Video: youtu.be/sLfyuQuH8F0
Video: youtu.be/sLfyuQuH8F0
Reposted by Alexander Ying
New research in @natgenet.nature.com from @danafarber.bsky.social’s @ckadoch.bsky.social and Jessica St. Laurent, MD, uncovers potential targeted therapy for endometrial cancer.
bit.ly/3Jq2Yxv
bit.ly/3Jq2Yxv
October 21, 2025 at 7:35 PM
New research in @natgenet.nature.com from @danafarber.bsky.social’s @ckadoch.bsky.social and Jessica St. Laurent, MD, uncovers potential targeted therapy for endometrial cancer.
bit.ly/3Jq2Yxv
bit.ly/3Jq2Yxv
Reposted by Alexander Ying
Super pleased to announce our latest suggesting the cell of origin for #SCLC is most likely the basal cell @nature.com, not the accepted neuroendocrine cell. Implications for the earliest events in cancer, & providing new models of tuft-like cancer.
rdcu.be/eGUtj
rdcu.be/eGUtj
Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer
Nature - Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining...
rdcu.be
September 17, 2025 at 3:21 PM
Super pleased to announce our latest suggesting the cell of origin for #SCLC is most likely the basal cell @nature.com, not the accepted neuroendocrine cell. Implications for the earliest events in cancer, & providing new models of tuft-like cancer.
rdcu.be/eGUtj
rdcu.be/eGUtj