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Aydin Lab

@aydinlab.bsky.social

100 followers 190 following 6 posts

Laboratory of Cell Biology and Biophysics. Investigates the molecular mechanisms of life processes in human health and disease. www.aydinlab.org

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Aydin Lab @aydinlab.bsky.social · 8d

Thank you Mimi :)

Aydin Lab @aydinlab.bsky.social · 8d

Excited to share that our paper on mitochondrial cardiolipin dynamics is published in @natcomms.nature.com today! We provide molecular explanations for unique aspects of mitochondrial morphology and the mechanisms underlying cardiolipin-related Barth Syndrome.
www.nature.com/articles/s41...

Cardiolipin dynamics promote membrane remodeling by mitochondrial OPA1 - Nature Communications

This study reveals how cardiolipin governs mitochondrial morphology by modulating the activity of human OPA1 and how its replacement by monolyso-cardiolipin, as observed in Barth syndrome, impacts mitochondrial membrane-shaping mechanisms.

www.nature.com

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Reposted by Aydin Lab

Aydogan Lab @aydoganlab.bsky.social · Aug 25

#Postdoc-opportunity at Columbia U. in New York!!

Looking for a postdoc position? We are interested in candidates from biochemistry background & excited about fractionation, purification and reconstitution to study autonomous clocks in the cell cycle, in colab. with @aydinlab.bsky.social at NYU!

Postdoctoral Scientist - Aydogan Lab

Primary Work Address: HHMI/Columbia University | Shadlen Lab--L5-003, New York, NY, 10027 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHM...

hhmi.wd1.myworkdayjobs.com

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NYU Pain Research Center @nyupainresearch.bsky.social · May 13

PRC Highlight: Welcome to the PRC-Structural Biologist Dr. Halil Aydin and Dr. Nestor Jimenez-our Director of the PRC e-phys core!! We are so excited to have you join the team! 👏🥳🎉

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Aydin Lab @aydinlab.bsky.social · Mar 8

I am happy to share that we recently moved our lab to NYU and are ready to do exciting science in the big apple! We are hiring talented postdocs for a variety of projects ranging from structural cell biology to molecular mechanisms of neurodegeration! Please reach out —> aydinlab.org

Aydin Lab @aydinlab.bsky.social · Apr 11

How do subcellular compartments communicate cellular signals? Our work on the regulation of mitochondrial fission by fatty acyl-coenzyme A is finally out in Nature Cell Biology! This was a great collaboration with the Higgs Lab at Dartmouth College. #mitochondria

www.nature.com/articles/s41...

Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51 - Nature Cell Biology

Liu et al. find that long-chain acyl-coenzyme A activates two mitochondrial fission proteins, MiD49 and MiD51, by inducing their oligomerization. This activates their ability to stimulate DRP1 GTPase ...

www.nature.com

Aydin Lab @aydinlab.bsky.social · Apr 9

Thank you Barth Syndrome Foundation for supporting our research! We will explore how disruptions in cardiolipin structure impact the regulation of mitochondrial function!

Aydin Lab @aydinlab.bsky.social · Dec 10

Mito symposium @ucla was a success! #mitochondria #cellbiology

Reposted by Aydin Lab

Karolin Luger @nucleosomepolice.bsky.social · Dec 8

So proud of @jonmarkert.bsky.social; can't wait to read it.

Lucas Farnung @lucas.farnunglab.com · Dec 8

Our paper on the structure of the complete Rpd3S-nucleosome complex is now out in Nat Comm: rdcu.be/ds6k1 . Congrats to @jonmarkert.bsky.social
and co-corresponding author Seychelle Vos! This is the second HDAC-nucleosome structure from Jon this year. Amazing!

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