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Ammar Zafar

@azmicro.bsky.social

68 followers 84 following 7 posts

Bacterial geneticist interested in host-pathogen interactions. Associate Professor at Emory University School of Medicine. Dept. of Microbiology & Immunology

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Ammar Zafar @azmicro.bsky.social · Aug 5

We have a protocols paper out led by fantastic post docs Juan Valencia-Bacca and Maidul Islam. More animal tools for the Kleb research community!!

Juan David Valencia Bacca @juanvalenciabacca.bsky.social · Aug 5

currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Our new article in Current Protocols is out: Microbiologists, immunologists, host-pathogen folks: this one’s for you 🧬🦠 #Klebsiella #HostPathogen #Microbiology
Huge thanks to my mentor @azmicro.bsky.social for the guidance and support!

Murine Models of Klebsiella pneumoniae Gastrointestinal Infection

Klebsiella pneumoniae (Kpn) is a Gram-negative opportunistic pathogen and a leading cause of hospital-acquired infections. The gastrointestinal (GI) tract serves as a critical site for Kpn colonizati....

currentprotocols.onlinelibrary.wiley.com

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Ammar Zafar @azmicro.bsky.social · Jul 1

Apparently only allows 10 free clicks to it 🙄

Ammar Zafar @azmicro.bsky.social · Jul 1

Our comprehensive review on bacterial transmission is out today in MMBR @asm.org, which took us ~2 years to put together. Thanks to Kim Walker @drwalkermsbanta.bsky.social and my graduate student, Giovanna Hernandez, for all the hard work they put into this review!

journals.asm.org/eprint/JIVRR...

Mechanisms of bacterial host-to-host transmission | Microbiology and Molecular Biology Reviews

SUMMARYBacterial pathogens must navigate complex host environments to thrive, replicate, and ultimately transmit to new hosts. Effective transmission is critical for pathogen propagation and often requires overcoming host defenses and exploiting ...

journals.asm.org

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Reposted by Ammar Zafar

Andreas Bäumler @abaumler.bsky.social · Apr 4

🚨 Big news! Infection and Immunity is now open access! 🌍🔬 That means wider visibility & impact for your research. Worried about fees? 💸 Check out how IAI stacks up against other journals—you might be surprised. #OpenAccess #SciComm #Microbiology

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Ammar Zafar @azmicro.bsky.social · Feb 28

Thanks Lauren!

Reposted by Ammar Zafar

Nature Communications @natcomms.nature.com · Feb 28

Klebsiella pneumoniae uses a type VI secretion system to overcome microbiota-mediated colonization resistance

@azmicro.bsky.social @emorydeptofmed.bsky.social

#microbiome #bacteria #pathogens #microbiology

www.nature.com/articles/s41...

Figure summarizing the regulatory effects induced by the gastrointestinal tract environment on Klebsiella pneumoniae, leading to T6SS-mediated killing of Betaproteobacteria.

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Ammar Zafar @azmicro.bsky.social · Feb 7

After 6 wonderful years at Wake Forest School of Medicine the Zafar lab is now officially open at Emory School of Medicine in the dept. of microbiology and immunology!

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Ammar Zafar @azmicro.bsky.social · Feb 4

Post Doc Juan Valencia-Bacca representing the Zafar/Haas lab at the mid-Atlantic microbial pathogenesis meeting #mampm describing the role of gut complement in controlling K pneumoniae!

Ammar Zafar @azmicro.bsky.social · Jan 28

First post! Our study in Nature Comms showing the importance of the T6SS of Klebsiella pneumoniae in gut colonization. We combined tn-seq with metagenomics and identified new microbiota targets and T6SS regulators.
Major thanks to Kim walker and Virginia Miller

www.nature.com/articles/s41...

Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance - Nature Communications

Through metagenomics, Bray et al. identified Klebsiella pneumoniae interacting microbiota partners in the gut, and a transposon mutagenesis screen revealed a role for its T6SS in gut colonization, wit...

www.nature.com

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