Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension. In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated systolic blood pr...

Abstract. Hepatitis C virus (HCV) infection remains a major cause of chronic liver disease and premature mortality worldwide. The World Health Organization

This randomized cluster trial investigates whether routine screening for Helicobacter pylori using urea breath tests among patients after acute myocardial infarction reduces upper gastrointestinal ble...

Advances in the understanding of multiple sclerosis and the development of biomarkers of pathophysiology prompted a substantial revision of the 2017 McDonald diagnostic criteria. The new 2024 McDonald...

Why do so many antibiotics get prescribed for a week? Is there something special about 7 days of therapy? Would we ever use the number 7 in any other context? The courses of antibiotics we prescribe are clearly not scientific, which has always made the lecture that patients receive about finishing their entire course of antibiotics sounds pretty stupid. Thankfully, a lot of attention has been paid to shortening antibiotic courses over the last few years.

Severe asthma affects 5-10% of asthma patients but constitutes close to half of the medical costs related to asthma due to higher morbidity and healthcare utilization. Biologic agents have become a st...

This secondary analysis of 2 randomized clinical trials assesses risk of cardiovascular disease due to hormone therapy in postmenopausal women with vasomotor symptoms.

BACKGROUND: ACE (angiotensin-converting enzyme) inhibitors and ARBs (angiotensin receptor blockers) are equally recommended as first-line treatment for cardiovascular and renal protection in clinical ...

Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable wi...

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Among patients who underwent CABG, evolocumab did not reduce SVG disease at 24 months following the index surgery despite substantial LDL-C lowering. Further LDL-C lowering does not appear to meaningf...

Aspirin reduces the incidence of colorectal adenoma and colorectal cancer among high-risk persons. Observational studies suggest that aspirin may also improve disease-free survival after diagnosis,...