Lightnews — Scholar-powered news

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Trudy G. Oliver @tgoliver.bsky.social · 25d

Super pleased to announce our latest suggesting the cell of origin for #SCLC is most likely the basal cell @nature.com, not the accepted neuroendocrine cell. Implications for the earliest events in cancer, & providing new models of tuft-like cancer.
rdcu.be/eGUtj

Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer

Nature - Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining...

rdcu.be

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CJ Fogler @cjzero.bsky.social · Aug 31

Spectacular from Szoboszlai

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Carl T. Bergstrom @carlbergstrom.com · Aug 8

1. Federal funding for research promotes tech, biomedical, and scientific discovery in the US, and provides training for the sci/tech workforce that has brought immeasurable wealth to the US over the past 75 years.

Today's executive order includes a provision that will obliterate both functions.

Improving Oversight of Federal Grantmaking

By the authority vested in me as President by the Constitution and the laws of the United States of America, and to improve the process of Federal

www.whitehouse.gov

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W.E.D.em Boyz @leftistwonk.bsky.social · Aug 6

Even hundreds of trucks would not be enough

"There are an increasing number of children that need to be in the hospital because they can’t eat food. They have got to that stage of severe acute malnutrition where their bodies just can’t digest food. And so those kids need to be in intensive care."

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John Foley @2008philz.bsky.social · Aug 5

Harrison Bader looks like all of the 1993 Phillies had a baby together

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John Foley @2008philz.bsky.social · Aug 2

Jhoan Duran intro at Citizens Bank Park

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frank @fgif.bsky.social · Jul 30

That Duran entrance is going to be wild at CBP, grab me a $17 yuengling and let’s ride

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Liz Essley Whyte @lizessleywhyte.bsky.social · Jul 29

NEW
The White House is blocking the NIH from awarding new research grants for the rest of the fiscal year

Chokes off billions in research funding

Gift link www.wsj.com/politics/pol... with @nidhisubs.bsky.social

Trump Administration Puts New Chokehold on Billions in Health-Research Funding

The National Institutes of Health can’t award grants to outside researchers under a new White House restriction.

www.wsj.com

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Daniel Mucida @danmucida.bsky.social · Jul 24

Heartless murderers. www.nytimes.com/2025/07/24/w...

Gazans Are Dying of Starvation

www.nytimes.com

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Nick Piccone @piccone.bsky.social · Jul 16

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United Farm Workers @ufw.bsky.social · Jul 13

Our hearts are heavy for the grieving family of Jaime Alanis, who died from injuries sustained during a chaotic raid on Thursday.

We will do everything we can to support them. We continue to work with the hundreds of farm worker families navigating the aftermath of this violent raid.

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Barzin Nabet @barzin-nabet.bsky.social · Jul 1

www.thelancet.com/journals/lan...

Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis

USAID funding has significantly contributed to the reduction in adult and child mortality across low-income and middle-income countries over the past two decades. Our estimates show that, unless the a...

www.thelancet.com

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Waggoner Lab @labwaggoner.bsky.social · Jun 30

Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity @cp-immunity.bsky.social
www.cell.com/immunity/ful...

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The Associated Press @apnews.com · Jun 24

BREAKING: Palestinian witnesses and hospitals say Israeli forces opened fire toward hundreds of people waiting for aid trucks in central Gaza, killing at least 25 people.

Israeli forces fire on people waiting for aid in Gaza, killing 25, witnesses and hospitals say

Palestinian witnesses say Israeli forces and drones opened fire toward hundreds of people waiting for aid trucks in central Gaza.

bit.ly

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Tim Onion @bencollins.bsky.social · Jun 22

theonion.com/this-war-wil...

This War Will Destabilize The Entire Mideast Region And Set Off A Global Shockwave Of Anti-Americanism vs. No It Won’t

George W. Bush may think that a war against Iraq is the solution to our problems, but the reality is, it will only serve to create far more.

theonion.com

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Meera Sundaram @meera-sundaram.bsky.social · Jun 11

#NoKings info for #Philly billypenn.com/2025/06/10/p...

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Musa Okwonga @okwonga.bsky.social · Jun 1

“More than 30 Palestinians were killed by Israeli fire on Sunday as they went to receive food at an aid distribution point set up by an Israeli-backed foundation in Gaza, according to witnesses, with a hospital run by the Red Cross confirming it was treating many wounded.”

الكسندرا ميراي @lexialex.bsky.social · Jun 1

www.theguardian.com/world/2025/j...

Palestinians gunned down while trying to reach food aid site in Gaza, hospital says

Witnesses say Israeli forces opened fire on people near distribution point run by Israel-backed foundation

www.theguardian.com

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charlesrudin.bsky.social @charlesrudin.bsky.social · May 26

First Bluesky post…
New paper out, following on FOXA observations of the @juliensage.bsky.social lab; nice collaboration with the @joanmassague.bsky.social lab led by a shared post-doc, Kenta Kawasaki www.nature.com/articles/s41...

FOXA2 promotes metastatic competence in small cell lung cancer - Nature Communications

Small cell lung cancer presents high and multi-site metastatic potential. Here, the authors discover that FOXA2, regulated by ASCL1, promotes multi-site metastasis in small cell lung cancer by inducin...

www.nature.com

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Max Kozlov @maxkozlov.bsky.social · May 21

Who's calling the shots at NIH?

Sworn testimonies and internal e-mails reveal for the first time the breadth of DOGE's control over the world's largest public biomedical funder.

DOGE has provided lists of hundreds of grants to cut, and DOGE is now reviewing ALL NIH awards before they're released

NIH killed grants on orders from Elon Musk’s DOGE

Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.

www.nature.com

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Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · May 15

We're excited to share that Dr. Andy Minn will return to Memorial Sloan Kettering Cancer Center (MSK) as the inaugural Chair of MSK’s new Immuno-Oncology Program in August.

Learn more about Dr. Minn: bit.ly/44Advyo

Andy Minn, MD, PhD, will rejoin Memorial Sloan Kettering Cancer Center as the Inaugural Chair of MSK’s new Immuno-Oncology Program

Andy Minn, MD, PhD, will return to Memorial Sloan Kettering Cancer Center (MSK) as the inaugural Chair of MSK’s new Immuno-Oncology Program in August.

bit.ly

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Julia Carrie Wong @joolia.bsky.social · May 8

“States must act now to end the violence or bear witness to the annihilation of the Palestinian population in Gaza – an outcome with irreversible consequences for our shared humanity”

End unfolding genocide or watch it end life in Gaza: UN experts say States face defining choice

GENEVA – Escalating atrocities in Gaza present an urgent moral crossroads and States must act now to end the violence or bear witness to the annihilation of the Palestinian population in Gaza – an out...

www.ohchr.org

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Barzin Nabet @barzin-nabet.bsky.social · Apr 29

Awesome work as usual from @davidmacphersonlab.bsky.social , wonderful to play a small part!

David MacPherson Lab @davidmacphersonlab.bsky.social · Apr 29

Our latest, in Science Advances: In vivo CRISPR screen revealed sgRNAs that switch chemosensitive SCLC PDXs to become resistant.We validated KEAP1 as key hit and found KEAP1 alterations in IMpower133 trial, where active NRF2 links to reduced survival in chemo arm www.science.org/doi/10.1126/... 1/2

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Lorena O’Neil @lorenaoneil.com · Apr 26

BREAKING: @aclu.org says Trump deported a child (U.S. citizen) with metastatic cancer without medication or consultation with physicians. This is the second child with cancer he's deported. www.rollingstone.com/politics/pol... @rollingstone.com

Trump Has Now Deported Multiple U.S. Citizen Children With Cancer

Two families who had lived in the United States for years, including a child with cancer and a pregnant mother, were deported by ICE on Friday.

www.rollingstone.com

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Kyle Cheney @kyledcheney.bsky.social · Apr 26

NEW: A federal judge raised alarm Friday that the Trump administration appeared to have deported a 2-year-old U.S. citizen to Honduras with "no meaningful process" — even as her father was fighting to keep her in the country.

Details w/ @joshgerstein.bsky.social

www.politico.com/news/2025/04...

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Edward Nirenberg @enirenberg.bsky.social · Apr 23

I don't get how anyone can possibly be okay with ending the WHI. This study has accrued decades of data from 42000 women and it is still going. It helps to address critical research gaps that have been allowed to go unfilled because of durable misogyny and provides invaluable insight into aging.

NIH cancels its first and largest study centered on women

The Women’s Health Initiative has produced numerous influential findings

www.science.org

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