@bbw9.bsky.social
Reposted
We’re delighted to report a global structural proteome analysis within living cells!
doi.org/10.1038/s443...
#proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social
doi.org/10.1038/s443...
#proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social
January 13, 2026 at 5:29 PM
We’re delighted to report a global structural proteome analysis within living cells!
doi.org/10.1038/s443...
#proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social
doi.org/10.1038/s443...
#proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social
Reposted
Serial enrichment based quantitative proteomics enables deep and multiplexed profiling of post-translational modifications www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
January 17, 2026 at 10:40 AM
Serial enrichment based quantitative proteomics enables deep and multiplexed profiling of post-translational modifications www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
Reposted
Harnessing New Tools for Old Challenges: Optimising Neat Plasma Proteomics with Automation and Gas-Phase Fractionation pubs.acs.org/doi/ful...
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#proteomics #prot-paper
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#proteomics #prot-paper
January 8, 2026 at 10:20 AM
Harnessing New Tools for Old Challenges: Optimising Neat Plasma Proteomics with Automation and Gas-Phase Fractionation pubs.acs.org/doi/ful...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
Protein:protein interactions are incredibly dynamic so how do we quantify and discover changes in native tissues? Our new study uses qXL-MS and PCP-MS to study dynamic remodeling of interactions following skeletal muscle insulin resistance. #MyoBlue #Proteomics www.biorxiv.org/content/10.6...
Quantitative interactome mapping of skeletal muscle insulin resistance
Protein-protein interactions (PPIs) are dynamic and critical to adaptive homeostasis. While there have been massive efforts to catalogue proteome-wide PPIs, global quantification of changes remains a ...
www.biorxiv.org
January 6, 2026 at 8:23 PM
Protein:protein interactions are incredibly dynamic so how do we quantify and discover changes in native tissues? Our new study uses qXL-MS and PCP-MS to study dynamic remodeling of interactions following skeletal muscle insulin resistance. #MyoBlue #Proteomics www.biorxiv.org/content/10.6...
Reposted
Native multi-dimensional (SEC/CZE/SID) protein complex identification and topology characterization (Native MudPIT) chemrxiv.org/engage/...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
January 6, 2026 at 10:45 AM
Native multi-dimensional (SEC/CZE/SID) protein complex identification and topology characterization (Native MudPIT) chemrxiv.org/engage/...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
Reposted
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
December 31, 2025 at 10:00 AM
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
Unified down-stream analysis of crosslinking mass spectrometry results with pyXLMS www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
December 22, 2025 at 12:40 PM
Unified down-stream analysis of crosslinking mass spectrometry results with pyXLMS www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
Reposted
SPAP: Soluble Human Plasma Proteoform Analysis via Acetonitrile Precipitation and Top-Down Mass Spectrometry pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
December 19, 2025 at 9:20 AM
SPAP: Soluble Human Plasma Proteoform Analysis via Acetonitrile Precipitation and Top-Down Mass Spectrometry pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
News in Proteomics Research blog post | Is that a peak? A pandemic remote learning success story! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
December 18, 2025 at 12:40 PM
News in Proteomics Research blog post | Is that a peak? A pandemic remote learning success story! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
Reposted
Accurate de novo sequencing of the modified proteome with OmniNovo arxiv.org/abs/2512.1...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
December 16, 2025 at 10:20 AM
Accurate de novo sequencing of the modified proteome with OmniNovo arxiv.org/abs/2512.1...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
Reposted
LCMSpector: A simple open-source viewer for targeted hyphenated mass spectrometry analysis journals.plos.org/pl...
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#proteomics #prot-paper
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#proteomics #prot-paper
December 16, 2025 at 10:00 AM
LCMSpector: A simple open-source viewer for targeted hyphenated mass spectrometry analysis journals.plos.org/pl...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
Propionic acid outperforms formic and acetic acid in MS sensitivity for high-flow reversed-phase LC-MS bottom-up proteomics chemrxiv.org/engage/...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
November 28, 2025 at 2:00 PM
Propionic acid outperforms formic and acetic acid in MS sensitivity for high-flow reversed-phase LC-MS bottom-up proteomics chemrxiv.org/engage/...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
Reposted
This “major update to ProteomicsDB” is definitely worth a look. academic.oup.com/nar/advance-...
Mapping drug mechanisms with ProteomicsDB: unified omics and cell sensitivity data at scale
Abstract. Proteomic and phenotypic cell sensitivity datasets are increasingly important for understanding chemoproteomics and the underlying drug mechanism
academic.oup.com
November 22, 2025 at 4:49 AM
This “major update to ProteomicsDB” is definitely worth a look. academic.oup.com/nar/advance-...
Reposted
The SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
November 20, 2025 at 11:20 AM
The SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
IBT-16plex-Based Quantitative Proteomics at the Single-Cell Level: Enabling Protein Profiles toward the Single Cells from Mouse Spleen pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
November 20, 2025 at 11:40 AM
IBT-16plex-Based Quantitative Proteomics at the Single-Cell Level: Enabling Protein Profiles toward the Single Cells from Mouse Spleen pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Profiling the proteome-wide selectivity of diverse electrophiles - Nature Chemistry
Covalent inhibitors are powerful entities in drug discovery. Now the amino acid selectivity and reactivity of a diverse electrophile library have been assessed proteome-wide using an unbiased workflow...
www.nature.com
October 30, 2025 at 10:27 AM
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Reposted
Structural proteomics of the human ubiquitinome www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
October 22, 2025 at 5:01 PM
Structural proteomics of the human ubiquitinome www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
Reposted
Spatial biology using single-cell mass spectrometry imaging and integrated microscopy www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
October 15, 2025 at 10:20 PM
Spatial biology using single-cell mass spectrometry imaging and integrated microscopy www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
Tear fluid proteomics: a comparative study of DIA and DDA mass spectrometry www.sciencedirect.co...
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#proteomics #prot-paper
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#proteomics #prot-paper
October 12, 2025 at 10:00 PM
Tear fluid proteomics: a comparative study of DIA and DDA mass spectrometry www.sciencedirect.co...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
Mapping cryptic phosphorylation sites in the human proteome | The EMBO Journal www.embopress.org/do...
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#proteomics #prot-paper
October 5, 2025 at 6:20 PM
Mapping cryptic phosphorylation sites in the human proteome | The EMBO Journal www.embopress.org/do...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted
What's the state-of-the-art in DIA XL-MS? #Proteomics #TeamMassSpec
October 2, 2025 at 5:36 PM
What's the state-of-the-art in DIA XL-MS? #Proteomics #TeamMassSpec
Reposted
New Developments in Plasma Proteomics | BioPharm International www.biopharminternat...
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#proteomics #prot-article
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#proteomics #prot-article
New Developments in Plasma Proteomics | BioPharm International
A single protein or gene expression product can exist in multiple proteoforms due to alternative splicing, point mutations, post translational modifications and endogenous proteolysis.
www.biopharminternational.com
September 27, 2025 at 1:20 PM
New Developments in Plasma Proteomics | BioPharm International www.biopharminternat...
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#proteomics #prot-article
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#proteomics #prot-article
Reposted
A standardized framework for circulating blood proteomics www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
September 23, 2025 at 5:40 PM
A standardized framework for circulating blood proteomics www.nature.com/artic...
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#proteomics #prot-paper
Reposted
Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs) www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
September 23, 2025 at 8:00 AM
Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs) www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint