MS Bioworks
@msbioworks.bsky.social
We productized proteomics services and tranformed the field. Here to discuss all things proteomics and occasionally stir the pot :)
Reposted by MS Bioworks
If Congress doesn’t act, the last nuclear arms control treaty between the U.S. and Russia will expire. It would pointlessly wipe out decades of diplomacy, and could spark another arms race that makes the world less safe. This piece is worth the read.
Opinion | Let the Arms Race Begin
www.nytimes.com
February 2, 2026 at 2:01 PM
If Congress doesn’t act, the last nuclear arms control treaty between the U.S. and Russia will expire. It would pointlessly wipe out decades of diplomacy, and could spark another arms race that makes the world less safe. This piece is worth the read.
Reposted by MS Bioworks
🔥 We’re hiring! A rare opportunity to rethink neurodegeneration:
🟦 Develop creative, rigorous approaches to data interpretation toward mechanistic insights.
Join our team at PTI to study neurodegenerative disease using direct protein analysis at single-cell resolution.
1/2
🟦 Develop creative, rigorous approaches to data interpretation toward mechanistic insights.
Join our team at PTI to study neurodegenerative disease using direct protein analysis at single-cell resolution.
1/2
February 2, 2026 at 1:03 PM
🔥 We’re hiring! A rare opportunity to rethink neurodegeneration:
🟦 Develop creative, rigorous approaches to data interpretation toward mechanistic insights.
Join our team at PTI to study neurodegenerative disease using direct protein analysis at single-cell resolution.
1/2
🟦 Develop creative, rigorous approaches to data interpretation toward mechanistic insights.
Join our team at PTI to study neurodegenerative disease using direct protein analysis at single-cell resolution.
1/2
Reposted by MS Bioworks
It is my great honor to announce that registration for the 7th ESCP Single Cell Proteomics Conference is now open: lnkd.in/e4iyiQjf
With around 250 participants, it is one of the largest SCP conferences worldwide. We are also proud to announce that there is no participation fee for our conference.
With around 250 participants, it is one of the largest SCP conferences worldwide. We are also proud to announce that there is no participation fee for our conference.
January 28, 2026 at 4:23 PM
It is my great honor to announce that registration for the 7th ESCP Single Cell Proteomics Conference is now open: lnkd.in/e4iyiQjf
With around 250 participants, it is one of the largest SCP conferences worldwide. We are also proud to announce that there is no participation fee for our conference.
With around 250 participants, it is one of the largest SCP conferences worldwide. We are also proud to announce that there is no participation fee for our conference.
Reposted by MS Bioworks
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free
Stay free
Bruce Springsteen - Streets Of Minneapolis (Official Audio)
YouTube video by Bruce Springsteen
youtu.be
January 28, 2026 at 5:02 PM
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free
Stay free
What software are you all using for QC of DIA data? #Proteomics
January 22, 2026 at 2:49 PM
What software are you all using for QC of DIA data? #Proteomics
Reposted by MS Bioworks
Applications are now open for @olgavitek.bsky.social 's May Intitute on computation and statistics for mass spectrometry and proteomics at @northeasternu.bsky.social !
--> computationalproteomics.khoury.northeastern.edu
--> computationalproteomics.khoury.northeastern.edu
May Institute – Computation and statistics for mass spectrometry and proteomics
computationalproteomics.khoury.northeastern.edu
January 20, 2026 at 11:26 PM
Applications are now open for @olgavitek.bsky.social 's May Intitute on computation and statistics for mass spectrometry and proteomics at @northeasternu.bsky.social !
--> computationalproteomics.khoury.northeastern.edu
--> computationalproteomics.khoury.northeastern.edu
This paper has me thinking.
www.nature.com/articles/s41...
Can we move towards a blockchain for peptide identifications? A community accessible record for an identification, requiring no further processing.
Something like peptide atlas but with batch mining.
Thinking out loud.
#Proteomics
www.nature.com/articles/s41...
Can we move towards a blockchain for peptide identifications? A community accessible record for an identification, requiring no further processing.
Something like peptide atlas but with batch mining.
Thinking out loud.
#Proteomics
Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics - Nature Communications
Several recent publications have attempted to detect novel unannotated microproteins using mass spectrometry proteomics. Here, the authors reassess these claimed microprotein detections, finding that ...
www.nature.com
January 21, 2026 at 5:19 PM
This paper has me thinking.
www.nature.com/articles/s41...
Can we move towards a blockchain for peptide identifications? A community accessible record for an identification, requiring no further processing.
Something like peptide atlas but with batch mining.
Thinking out loud.
#Proteomics
www.nature.com/articles/s41...
Can we move towards a blockchain for peptide identifications? A community accessible record for an identification, requiring no further processing.
Something like peptide atlas but with batch mining.
Thinking out loud.
#Proteomics
Reposted by MS Bioworks
Pew Research Institute (2023):
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
January 18, 2026 at 9:03 PM
Pew Research Institute (2023):
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
Another photo from the pump failure. Quite a doozy. On the plus side the service contract will cover this and with the new parts the instrument will be tip-top. This is a Lumos BTW, we use it for DDA HCD/EThcD on immunopeptidome samples.
January 17, 2026 at 10:21 PM
Another photo from the pump failure. Quite a doozy. On the plus side the service contract will cover this and with the new parts the instrument will be tip-top. This is a Lumos BTW, we use it for DDA HCD/EThcD on immunopeptidome samples.
GLORY GLORY MAN UTD! What a start to the year. Upwards we go! COME ON!
January 17, 2026 at 2:41 PM
GLORY GLORY MAN UTD! What a start to the year. Upwards we go! COME ON!
This might be the problem.... #TeamMassSpec
January 16, 2026 at 7:35 PM
This might be the problem.... #TeamMassSpec
Cool papers keep coming and it's only January. Multi-scale classification decodes the complexity of the human E3 ligome. Figure 3 is a beaut!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multi-scale classification decodes the complexity of the human E3 ligome - Nature Communications
The authors of this study map the human E3 ubiquitin ligome using a metric learning approach, revealing a unified classification framework that explains preserved patterns and functional segregation o...
www.nature.com
January 16, 2026 at 2:58 PM
Cool papers keep coming and it's only January. Multi-scale classification decodes the complexity of the human E3 ligome. Figure 3 is a beaut!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Early front runner for paper of the year
pubs.acs.org/doi/10.1021/...
Super interesting ML stuff for peptide fragmentation in the associated github.com/PayneLab/Pro...
#Proteomics #TeamMassSpec
pubs.acs.org/doi/10.1021/...
Super interesting ML stuff for peptide fragmentation in the associated github.com/PayneLab/Pro...
#Proteomics #TeamMassSpec
pubs.acs.org
January 14, 2026 at 7:16 PM
Early front runner for paper of the year
pubs.acs.org/doi/10.1021/...
Super interesting ML stuff for peptide fragmentation in the associated github.com/PayneLab/Pro...
#Proteomics #TeamMassSpec
pubs.acs.org/doi/10.1021/...
Super interesting ML stuff for peptide fragmentation in the associated github.com/PayneLab/Pro...
#Proteomics #TeamMassSpec
Speaking of #AgenticAI somebody made an #MCP server for the OpenTrons robot! We're going to have a crack with #N8N and an OT2. If anyone is interested let me know.
github.com/yerbymatey/o...
github.com/yerbymatey/o...
GitHub - yerbymatey/opentrons-mcp: mcp server for robot automation + api documentation
mcp server for robot automation + api documentation - yerbymatey/opentrons-mcp
github.com
January 13, 2026 at 8:15 PM
Speaking of #AgenticAI somebody made an #MCP server for the OpenTrons robot! We're going to have a crack with #N8N and an OT2. If anyone is interested let me know.
github.com/yerbymatey/o...
github.com/yerbymatey/o...
After about 250 million years of doing mass spec I can conclude that isotope patterns never get boring. They are just a beautiful solution to a problem. #TeamMassSpec
January 13, 2026 at 2:38 PM
After about 250 million years of doing mass spec I can conclude that isotope patterns never get boring. They are just a beautiful solution to a problem. #TeamMassSpec
Reposted by MS Bioworks
A lawsuit by Alzheimer’s disease drugmaker T3D Therapeutics accuses five South Florida testing sites of falsification of data and other fraud in a test of an experimental compound, T3D-959. https://scim.ag/3Lu2pDP
Alzheimer’s drug developers accuse clinical trial sites of faking data
T3D Therapeutics alleges that contract researchers delivered “medically impossible” results on its candidate drug
scim.ag
January 9, 2026 at 2:23 PM
A lawsuit by Alzheimer’s disease drugmaker T3D Therapeutics accuses five South Florida testing sites of falsification of data and other fraud in a test of an experimental compound, T3D-959. https://scim.ag/3Lu2pDP
Reposted by MS Bioworks
I’m running for Congress in NY-12, my home.
We have a demented, criminal president running the country like a mob operation—government by the boss, for the boss.
We need Democratic fighters who will defend the rule of law and deliver government by the people. Join us.
We have a demented, criminal president running the country like a mob operation—government by the boss, for the boss.
We need Democratic fighters who will defend the rule of law and deliver government by the people. Join us.
January 6, 2026 at 11:59 AM
I’m running for Congress in NY-12, my home.
We have a demented, criminal president running the country like a mob operation—government by the boss, for the boss.
We need Democratic fighters who will defend the rule of law and deliver government by the people. Join us.
We have a demented, criminal president running the country like a mob operation—government by the boss, for the boss.
We need Democratic fighters who will defend the rule of law and deliver government by the people. Join us.
Let's have a review of how your LC systems behaved over the holiday break. We'll go first, M-Class systems as usual solid as a rock. The Neo's... more scripts than Seinfeld!
January 5, 2026 at 8:59 PM
Let's have a review of how your LC systems behaved over the holiday break. We'll go first, M-Class systems as usual solid as a rock. The Neo's... more scripts than Seinfeld!
Reposted by MS Bioworks
Are you interested in a postdoctoral position? Do you have experience in mitochondrial biology and in vivo research? Please send me your CV!
January 5, 2026 at 1:25 PM
Are you interested in a postdoctoral position? Do you have experience in mitochondrial biology and in vivo research? Please send me your CV!
Haptenated MHC peptides are all the rage. Really nice example here. #Proteomics #TeamMassSpec
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Engineered antibodies that stabilize drug-modified KRASG12C neoantigens enable selective and potent cross-HLA immunotherapy - Nature Communications
Covalent KRAS inhibitors show initial responses but resistance limits durability. Here drug-induced hapten peptides are identified and characterized, enabling production of high affinity, cross-HLA T ...
www.nature.com
December 21, 2025 at 5:50 PM
Haptenated MHC peptides are all the rage. Really nice example here. #Proteomics #TeamMassSpec
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Good reason to subscribe to @aaas.org @science.org I spotted this one while reading last night. Amazing bit of DNA cross-linking analysis www.science.org/doi/10.1126/...
Protein-Protein cross linking is going to a be an emerging force in 2026 for sure. #TeamMassSpec
Protein-Protein cross linking is going to a be an emerging force in 2026 for sure. #TeamMassSpec
December 18, 2025 at 2:54 PM
Good reason to subscribe to @aaas.org @science.org I spotted this one while reading last night. Amazing bit of DNA cross-linking analysis www.science.org/doi/10.1126/...
Protein-Protein cross linking is going to a be an emerging force in 2026 for sure. #TeamMassSpec
Protein-Protein cross linking is going to a be an emerging force in 2026 for sure. #TeamMassSpec
LOL!
Merriam-Webster’s human editors have chosen ‘slop’ as the 2025 Word of the Year.
December 15, 2025 at 5:27 PM
LOL!
Veo 3.1 2025
It's time to break out the AI folks :) Crank up the volume for this one!
December 15, 2025 at 5:12 PM
Veo 3.1 2025