MS Bioworks
@msbioworks.bsky.social
We productized proteomics services and tranformed the field. Here to discuss all things proteomics and occasionally stir the pot :)
#Proteomics folks @thermofishersci.bsky.social is having a 3 for 2 Christmas sale that includes TMT reagents
www.thermofisher.com/us/en/home/p...
www.thermofisher.com/us/en/home/p...
3 for 2 Savings | Thermo Fisher Scientific - US
Buy 2 qualifying Thermo Fisher Scientific products and get the 3rd free. Enjoy 33% savings on research essentials through December 31.
www.thermofisher.com
December 9, 2025 at 1:47 PM
#Proteomics folks @thermofishersci.bsky.social is having a 3 for 2 Christmas sale that includes TMT reagents
www.thermofisher.com/us/en/home/p...
www.thermofisher.com/us/en/home/p...
Reposted by MS Bioworks
Know your rights. Protect your neighbors.
New York is — and always will be — a city for all immigrants.
New York is — and always will be — a city for all immigrants.
December 7, 2025 at 5:03 PM
Know your rights. Protect your neighbors.
New York is — and always will be — a city for all immigrants.
New York is — and always will be — a city for all immigrants.
Reposted by MS Bioworks
We are delighted to release 𝐃𝐈𝐀-𝐍𝐍 𝟐.𝟑.𝟏, with a groundbreaking 𝐈𝐧𝐟𝐢𝐧𝐃𝐈𝐀 module for fast searches against huge databases and support for 𝐃𝐃𝐀 data.
Release notes: github.com/vdemichev/Di...
Release notes: github.com/vdemichev/Di...
December 5, 2025 at 11:51 AM
We are delighted to release 𝐃𝐈𝐀-𝐍𝐍 𝟐.𝟑.𝟏, with a groundbreaking 𝐈𝐧𝐟𝐢𝐧𝐃𝐈𝐀 module for fast searches against huge databases and support for 𝐃𝐃𝐀 data.
Release notes: github.com/vdemichev/Di...
Release notes: github.com/vdemichev/Di...
Reposted by MS Bioworks
Happy to share our cryoEM Ensemble Optimization method! 🎉It infers optimal structures and their weights directly from individual cryoEM images - no maps just physics! with David Sliva-Sánchez, @erikhthiede.bsky.social & Roy Lederman www.biorxiv.org/content/10.6...
Cryo-electron microscopy ensemble optimization using individual particles and physical constraints
Biomolecules are inherently dynamic, and understanding their conformational ensemble distributions is essential for understanding their dynamics and biological roles. Cryo-electron microscopy (cryo-EM...
www.biorxiv.org
December 5, 2025 at 4:13 PM
Happy to share our cryoEM Ensemble Optimization method! 🎉It infers optimal structures and their weights directly from individual cryoEM images - no maps just physics! with David Sliva-Sánchez, @erikhthiede.bsky.social & Roy Lederman www.biorxiv.org/content/10.6...
Has anyone ever used Ardia and thought "mmm, that was a great experience"? #TotallyInfuriating
December 5, 2025 at 2:51 PM
Has anyone ever used Ardia and thought "mmm, that was a great experience"? #TotallyInfuriating
Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism
Mitochondria-lipid droplet (LD) interactions play a critical role in lipid metabolism and the progression of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). However, the dynamic ...
www.biorxiv.org
November 25, 2025 at 2:31 PM
Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The Stone Roses - Fools Gold (Official Video)
YouTube video by StoneRosesVEVO
www.youtube.com
November 20, 2025 at 8:17 PM
We lost a good one today folks. No Mani, no Fools Gold
#StoneRoses #LiveForever #Mani
www.bbc.com/news/article...
#StoneRoses #LiveForever #Mani
www.bbc.com/news/article...
Gary 'Mani' Mounfield: Stone Roses and Primal Scream bassist dies aged 63
The Stone Roses pay tribute to "our wonderful brother" Gary 'Mani' Mounfield after his death aged 63.
www.bbc.com
November 20, 2025 at 8:07 PM
We lost a good one today folks. No Mani, no Fools Gold
#StoneRoses #LiveForever #Mani
www.bbc.com/news/article...
#StoneRoses #LiveForever #Mani
www.bbc.com/news/article...
The Astral Zoom paper is here: www.biorxiv.org/content/10.1...
Bravo to @jesperolsenlab.bsky.social for this notable comment:
"Notably, for both DIA-NN and Spectronaut,
inference to protein-coding genes was done via gene names, to avoid inflation of identification
rates via isoforms.
Bravo to @jesperolsenlab.bsky.social for this notable comment:
"Notably, for both DIA-NN and Spectronaut,
inference to protein-coding genes was done via gene names, to avoid inflation of identification
rates via isoforms.
From HeLa to human blood: extending single-cell proteomics to the smallest immune cells
Single-cell proteomics (SCP) holds the promise of decoding cellular heterogeneity at the functional level, yet achieving deep and reproducible proteome coverage from individual cells has remained a fo...
www.biorxiv.org
November 13, 2025 at 11:07 PM
The Astral Zoom paper is here: www.biorxiv.org/content/10.1...
Bravo to @jesperolsenlab.bsky.social for this notable comment:
"Notably, for both DIA-NN and Spectronaut,
inference to protein-coding genes was done via gene names, to avoid inflation of identification
rates via isoforms.
Bravo to @jesperolsenlab.bsky.social for this notable comment:
"Notably, for both DIA-NN and Spectronaut,
inference to protein-coding genes was done via gene names, to avoid inflation of identification
rates via isoforms.
Reposted by MS Bioworks
The NCBI nr FASTA file of protein sequences is no longer updated. We've summarised instructions for creating it from the BLAST database -- or you may be better off using TrEMBL.
www.matrixscience.com/blog/replace...
#proteomics #massspec
www.matrixscience.com/blog/replace...
#proteomics #massspec
Replacements for NCBI nr
www.matrixscience.com
November 10, 2025 at 2:46 PM
The NCBI nr FASTA file of protein sequences is no longer updated. We've summarised instructions for creating it from the BLAST database -- or you may be better off using TrEMBL.
www.matrixscience.com/blog/replace...
#proteomics #massspec
www.matrixscience.com/blog/replace...
#proteomics #massspec
Reposted by MS Bioworks
100 Python Projects — From Beginner to Expert
pythonclcoding.gumroad.com/l/100PythonP...
pythonclcoding.gumroad.com/l/100PythonP...
November 8, 2025 at 6:00 PM
100 Python Projects — From Beginner to Expert
pythonclcoding.gumroad.com/l/100PythonP...
pythonclcoding.gumroad.com/l/100PythonP...
Using @n8n.io a @Lego Buildhat for a @raspberrypi.com, an MCP server care of @anthropic.com and inspired by @jeffgeerling.com and @Networkchuck my son and I just made Agentic Lego!!! Tomorrow Art! MCP servers rule!
November 7, 2025 at 1:38 AM
Using @n8n.io a @Lego Buildhat for a @raspberrypi.com, an MCP server care of @anthropic.com and inspired by @jeffgeerling.com and @Networkchuck my son and I just made Agentic Lego!!! Tomorrow Art! MCP servers rule!
Look, can we all agree that $1TN is insufficient for HRH Elon Musks pay packet? He deserves more than this, I wont rest until he gets $10TN. How's a guy gonna get by on $1TN?!?!
November 7, 2025 at 12:56 AM
Look, can we all agree that $1TN is insufficient for HRH Elon Musks pay packet? He deserves more than this, I wont rest until he gets $10TN. How's a guy gonna get by on $1TN?!?!
Can anyone send me the link to the @pelosi.house.gov crowd funder? Poor gals gonna be broke after sticking it out in that government job for 20 years.
November 7, 2025 at 12:53 AM
Can anyone send me the link to the @pelosi.house.gov crowd funder? Poor gals gonna be broke after sticking it out in that government job for 20 years.
#TeamMassSpec #Proteomics folks is anybody working with this on an OT2 github.com/yerbymatey/o...?
@opentrons-lissette.bsky.social
@opentrons-lissette.bsky.social
GitHub - yerbymatey/opentrons-mcp: mcp server for robot automation + api documentation
mcp server for robot automation + api documentation - yerbymatey/opentrons-mcp
github.com
November 4, 2025 at 6:03 PM
#TeamMassSpec #Proteomics folks is anybody working with this on an OT2 github.com/yerbymatey/o...?
@opentrons-lissette.bsky.social
@opentrons-lissette.bsky.social
Reposted by MS Bioworks
Our Institute Director, Professor Samra Turajlić, will be giving a public talk at @crick.ac.uk
💬Crick Crash Course: Immunotherapy
📅Wed 19th Nov
🕙10am
📌Crick Institute, London
For full details and to book: www.eventbrite.co.uk/e/crick-cras...
@turajliclab.bsky.social #Immunotherapy
💬Crick Crash Course: Immunotherapy
📅Wed 19th Nov
🕙10am
📌Crick Institute, London
For full details and to book: www.eventbrite.co.uk/e/crick-cras...
@turajliclab.bsky.social #Immunotherapy
November 4, 2025 at 11:54 AM
Our Institute Director, Professor Samra Turajlić, will be giving a public talk at @crick.ac.uk
💬Crick Crash Course: Immunotherapy
📅Wed 19th Nov
🕙10am
📌Crick Institute, London
For full details and to book: www.eventbrite.co.uk/e/crick-cras...
@turajliclab.bsky.social #Immunotherapy
💬Crick Crash Course: Immunotherapy
📅Wed 19th Nov
🕙10am
📌Crick Institute, London
For full details and to book: www.eventbrite.co.uk/e/crick-cras...
@turajliclab.bsky.social #Immunotherapy
This is a pretty cool opportunity view.ceros.com/somalogic/25...
2025 SomaScan Grant Landing Page
view.ceros.com
November 3, 2025 at 4:12 PM
This is a pretty cool opportunity view.ceros.com/somalogic/25...
Reposted by MS Bioworks
How selective is your favourite electrophile? 🤔 🧪 🧫 🎯
Check out this thorough study from the @stephanhacker2.bsky.social lab, now published in Nature Chemistry!
Many congrats to everyone. We are thrilled to have contributed a little! Many congrats to @klanglab.bsky.social alumni Kristina and Marko!
Check out this thorough study from the @stephanhacker2.bsky.social lab, now published in Nature Chemistry!
Many congrats to everyone. We are thrilled to have contributed a little! Many congrats to @klanglab.bsky.social alumni Kristina and Marko!
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Profiling the proteome-wide selectivity of diverse electrophiles - Nature Chemistry
Covalent inhibitors are powerful entities in drug discovery. Now the amino acid selectivity and reactivity of a diverse electrophile library have been assessed proteome-wide using an unbiased workflow...
www.nature.com
October 30, 2025 at 2:39 PM
How selective is your favourite electrophile? 🤔 🧪 🧫 🎯
Check out this thorough study from the @stephanhacker2.bsky.social lab, now published in Nature Chemistry!
Many congrats to everyone. We are thrilled to have contributed a little! Many congrats to @klanglab.bsky.social alumni Kristina and Marko!
Check out this thorough study from the @stephanhacker2.bsky.social lab, now published in Nature Chemistry!
Many congrats to everyone. We are thrilled to have contributed a little! Many congrats to @klanglab.bsky.social alumni Kristina and Marko!
Attended a thought provoking presentation yesterday "The Future of AI for Society: Collaboration, upskilling and transforming together" given by @diyiyang.bsky.social Check out her labs work here: cs.stanford.edu/~diyiy/ and her teaching materials here: web.stanford.edu/class/cs329x/
Diyi Yang
cs.stanford.edu
October 30, 2025 at 1:37 PM
Attended a thought provoking presentation yesterday "The Future of AI for Society: Collaboration, upskilling and transforming together" given by @diyiyang.bsky.social Check out her labs work here: cs.stanford.edu/~diyiy/ and her teaching materials here: web.stanford.edu/class/cs329x/
Reposted by MS Bioworks
Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.
a spongebob squarepants scene with a mailbox and a flower
ALT: a spongebob squarepants scene with a mailbox and a flower
media.tenor.com
October 28, 2025 at 4:39 PM
Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.
While you were thinking AI is going to destroy us nobody noticed this happened....
October 29, 2025 at 1:07 AM
While you were thinking AI is going to destroy us nobody noticed this happened....
Reposted by MS Bioworks
Y'all. It's a HUGE day here on the ol' @wired.com because we have a giant package of stories on AI. Like deep, dark reporting on everything AI is doing to our world. I'll call out some favorite stories on subsequent posts, but for now—pick a card, any card
www.wired.com/ai-issue/
www.wired.com/ai-issue/
AI of a Thousand Faces
What happens now that AI is everywhere and in everything? WIRED can’t tell the future, but we can try to make sense of it. Behold: 17 readings from the furthest reaches of the AI age.
www.wired.com
October 27, 2025 at 7:06 PM
Y'all. It's a HUGE day here on the ol' @wired.com because we have a giant package of stories on AI. Like deep, dark reporting on everything AI is doing to our world. I'll call out some favorite stories on subsequent posts, but for now—pick a card, any card
www.wired.com/ai-issue/
www.wired.com/ai-issue/