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Benoît Zuber @benoitzuber.bsky.social · 27d

Paper alert🚨
Label your protein of interest and localize it in cryoET 👁️❄️

Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...

Genetically encoded FerriTag as a specific label for cryo-electron tomography

Wang et al. present an optimized labeling strategy for cryo-electron tomography based on genetically encoded FerriTag. This system uses rapamycin to recruit iron-loaded ferritin to target proteins, en...

www.cell.com

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Reposted by Benoît Zuber

Marc Bühler @marcbuhler.bsky.social · Sep 8

We are hiring-join us!

FMI science @fmiscience.bsky.social · Sep 8

🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...

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Benoît Zuber @benoitzuber.bsky.social · Jul 4

In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor
🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins
doi.org/10.1101/2025...

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Benoît Zuber @benoitzuber.bsky.social · Jul 2

A plain language overview of our recent publication link.growkudos.com/1bt0psurksg

Near-atomic detail from large sample areas using cryo-EM of frozen biological sample slices

This study explores how cryo-electron microscopy (cryo-EM) can be used to image large areas of frozen biological samples with near-atomic resolution. The researchers used a method called CEMOVIS, whic...

link.growkudos.com

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Benoît Zuber @benoitzuber.bsky.social · Jun 25

Out now at IUCJ doi.org/10.1107/S205...

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Benoît Zuber @benoitzuber.bsky.social · Apr 1

Happy to announce our latest preprint. High resolution ribosomes in cells obtained on CEMOVIS (frozen-hydrated sections) www.biorxiv.org/content/10.1... in collaboration with @grigoriefflab.bsky.social and Wanda Kukulski.

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Benoît Zuber @benoitzuber.bsky.social · Apr 1

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Reposted by Benoît Zuber

Grigorieff Lab @UMassChan and @HHMI @grigoriefflab.bsky.social · Mar 31

www.biorxiv.org/content/10.1...

NEW PREPRINT ALERT!
Thanks to all involved!

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Reposted by Benoît Zuber

fotiadislab.bsky.social @fotiadislab.bsky.social · Mar 19

Please check out our latest cryo-EM structure in the Journal of Structural Biology X: Structure of the PTS glucose transporter IICB stalled in an intermediate conformation.

www.sciencedirect.com/science/arti...

Congratulations Patrick for this great work !

Cryo-EM structure of a phosphotransferase system glucose transporter stalled in an intermediate conformation

The phosphotransferase system glucose-specific transporter IICBGlc serves as a central nutrient uptake system in bacteria. It transports glucose acros…

www.sciencedirect.com

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Reposted by Benoît Zuber

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · Feb 3

Great position for a postdoc to join @igreger.bsky.social’s group in the LMB’s Neurobiology Division, using diverse methods to study synaptic AMPA glutamate receptors.
Read more about the job here: www.nature.com/naturecareer...
Apply by 20 FEB
#PostdocJobs #ScienceJobs

Ingo Greger sat in front of a computer screen displaying an AMPA Receptor structure

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Reposted by Benoît Zuber

Sjors Scheres @sjorsscheres.bsky.social · Feb 3

Come and set up your own group at the @mrclmb.bsky.social in Cambridge, UK. Feel free to chat/email me with questions.

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · Jan 30

Join our Structural Studies Division, leading a research group developing computational methods to address questions in molecular & cellular biology!
You will be supported by core funding, excellent facilities & enthusiastic colleagues.
Apply by 18 MAR
www.nature.com/naturecareer...

Now hiring:
Research Group Leader
Structural Studies Division
To develop artificial intelligence/machine-learning methods to further our understanding of biology at molecular and/or cellular scales
Apply by 18th March

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Benoît Zuber @benoitzuber.bsky.social · Feb 4

Our latest JACS paper: high-resolution cryoEM of #aerolysin in lipid environment shows pore properties and 4 key constriction rings for #nanopore sensing. Collaboration with #DalPeraro & #Cao labs.
@coldpopeye.bsky.social
@unibern.bsky.social
#EPFL #UNIGE #DubochetCenter #MIC
shorturl.at/qyzbb

Aerolysin Nanopore Structures Revealed at High Resolution in a Lipid Environment

Aerolysin is a β-pore-forming toxin produced by most Aeromonas bacteria, which has attracted large attention in the field of nanopore sensing due to its narrow and charged pore lumen. Structurally sim...

shorturl.at

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Reposted by Benoît Zuber

Reymond Group @reymondgroup.bsky.social · Jan 6

🎉Our latest publication "Predicting Polypharmacology with Web-Based Tools" by @maedehdarsaraee.bsky.social, Sacha Javor, and Jean-Louis Reymond is now published on Wiley!
Read it here👉
onlinelibrary.wiley.com/doi/abs/10.1...

#DCBP
#polypharmacology
#target_prediction
#chembl
#fingerprint
#ML

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Reposted by Benoît Zuber

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · Jan 6

Reminder:
Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative!

You will be supported by core funding, excellent facilities and a lively international community of researchers.

Apply by 19 Jan

www.nature.com/naturecareer...

Now hiring:
Research Group Leader
To join the LMB’s Neurobiology Division and develop an independent research programme in the field of molecular connectomics, supported by core funding, excellent research facilities, and a lively community of colleagues.
Apply by 19th January 2025.
Background shows a connectomic map of an adult fly brain.

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Reposted by Benoît Zuber

Journal of Cell Biology @jcb.org · Jan 6

Our January cover shows a reconstructed synapse from a cryo-electron tomogram of cultured hippocampal neurons expressing a SNAP-25 mutant, using CryoVesNet developed by Amin Khosrozadeh, Benoît Zuber et al. (https://buff.ly/4h0DjGN).
JCB's January issue is here ✨ https://buff.ly/3ZZLqwE

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