bergeronlab.bsky.social
Bergeron lab
@bergeronlab.bsky.social
650 followers 570 following 10 posts
Structural biology, and beer. Not necessarily in that order.
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 30
The peer-reviewed version of Sash and Iryna’s paper on the Tad pilus is out:
The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension - Nature Communications
The Tad pilus is involved in the formation of antibiotic-resistant biofilms in many bacteria, including the human pathogen Pseudomonas aeruginosa. The authors report the structure of the Tad pilus pro...
www.nature.com
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Sep 1
That is very cool.
tbharat-lab.bsky.social
Tanmay Bharat @tbharat-lab.bsky.social · Aug 31
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Aug 1
Pure coincidence 😜
Reposted by Bergeron lab
cryoempapers.bsky.social
cryoEM papers @cryoempapers.bsky.social · Jul 30
The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension pubmed.ncbi.nlm.nih.gov/40730569/ #cryoem
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 30
The peer-reviewed version of Sash and Iryna’s paper on the Tad pilus is out:
The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension - Nature Communications
The Tad pilus is involved in the formation of antibiotic-resistant biofilms in many bacteria, including the human pathogen Pseudomonas aeruginosa. The authors report the structure of the Tad pilus pro...
www.nature.com
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 17
That’s also what I thought initially… then I looked closer…
bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 16
Hmmmm… there’s a, let’s call it “interesting” new sculpture at the entrance of the @crick.ac.uk . I’m curious to hear what this is meant to illustrate.
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 8
Superb work from our lab neighbours!
athertonlabkcl.bsky.social
Atherton Lab KCL @athertonlabkcl.bsky.social · Jul 7
Excited to see our @natcomms.nature.com paper out! #Cryo-EM reveals a #microtubule stimulated ADP-release transition state of #kinesin 1. The auto-inhibitory tail has no affect on motor domain conformations. Focussed subunit processing helps! #cryoEM #microtubules

www.nature.com/articles/s41...
Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail - Nature Communications
Kinesin-1 utilizes ATP-driven conformational changes to transport vital intracellular cargoes along microtubules. The authors use cryo-EM to reveal a missing structural transition state of the kinesin...
www.nature.com
Reposted by Bergeron lab
kingslsm.bsky.social
King's Faculty of Life Sciences & Medicine @kingslsm.bsky.social · Jul 7
In a new study, @bergeronlab.bsky.social have used the world’s most advanced electron microscope to reveal the complete architecture of the bacterial flagellum - a molecular machine essential for bacteria to cause infection, that could also be a target for antibiotics ⬇️ www.kcl.ac.uk/news/scienti...
Scientists target 'molecular machine' in the war against antimicrobial resistance
Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.
www.kcl.ac.uk
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Reposted by Bergeron lab
natmicrobiol.nature.com
Nature Microbiology @natmicrobiol.nature.com · Jul 1
#NewResearch

🚨Out now!

Structural analyses of the extracellular flagellum shows mechanism for flagellin incorporation

#MicroSky 🦠

www.nature.com/articles/s41...
The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology
Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...
www.nature.com
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 1
A lovely write-up from Kings about our latest paper, and its role in combating antibiotic resistance:
Scientists target 'molecular machine' in the war against antimicrobial resistance
Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.
www.kcl.ac.uk
bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Jul 1
The peer-reviewed version of our article on the flagellum filament assembly is out!
A masterpiece from duo extraordinaire Kailin and Rosa, and an incredibly productive collaboration with Marc Erhardt and Morgan Beeby.
The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology
Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...
www.nature.com
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Reposted by Bergeron lab
npariente.bsky.social
Nonia Pariente @npariente.bsky.social · Mar 25
When they go low, you go high, said a very wise woman

Just goes to show how pathetic Europe is exactly 💪🏻🧪

(Well done European Commission and ERC)
clanicholson.bsky.social
Craig Nicholson @clanicholson.bsky.social · Mar 25
ERC doubling funding to lure researchers to the EU

www.researchprofessionalnews.com/rr-news-euro...
ERC doubling funding to lure researchers to the EU - Research Professional News
Commission also planning a dedicated meeting to coordinate similar efforts among member states
www.researchprofessionalnews.com
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Reposted by Bergeron lab
cryoempapers.bsky.social
cryoEM papers @cryoempapers.bsky.social · Mar 13
A family of bacterial actin homologs forms a three-stranded tubular structure pubmed.ncbi.nlm.nih.gov/40073056/ #cryoem
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Mar 13
Latest paper from the lab: the Cryo-EM structure of BeeR! (Yes we did name the protein. No it’s not a coincidence)
A family of bacterial actin homologs forms a three-stranded tubular structure | PNAS
The cytoskeleton is crucial for cell organization and movement. In Eukaryotes, it largely consists of the protein actin, that forms a double-strand...
www.pnas.org
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Reposted by Bergeron lab
cryoempapers.bsky.social
cryoEM papers @cryoempapers.bsky.social · Feb 9
Curvature generation and engineering principles from Shewanella oneidensis multi-flagellin flagellum www.biorxiv.org/content/10.1101/2025.02.07.637127v1 #cryoem
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Reposted by Bergeron lab
davidroper2.bsky.social
davidroper2.bsky.social @davidroper2.bsky.social · Jan 7
We are a little behind schedule, but the line up for the Next Great Wall Symposium in Sicily in September is coming together more soon. Get ready for those applications for abstracts!!!
thegreatwall-symposium.org
The Greatwall-symposium
The Great Wall Symposium will take place from 18th to 20th September 2023 at the venue in The Vila Galé Sintra Hotel, in Portugal.
thegreatwall-symposium.org
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Reposted by Bergeron lab
kshbeckham.bsky.social
Kate Beckham @kshbeckham.bsky.social · Jan 6
First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group.
Deadline end of February.
Please spread the word. www.findaphd.com/phds/projectdetails.aspx?PJID=181239
PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University on FindAPhD.com
PhD Project - PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University, listed on FindAPhD.com
www.findaphd.com
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bergeronlab.bsky.social
Bergeron lab @bergeronlab.bsky.social · Nov 14
Thanks!
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